136 related articles for article (PubMed ID: 30773850)
1. Targeting PAK1 with the Small Molecule Drug AK963/40708899 Suppresses Gastric Cancer Cell Proliferation and Invasion by Downregulation of PAK1 Activity and PAK1-Related Signaling Pathways.
Zhou Y; Zhang J; Wang J; Cheng MS; Zhao DM; Li F
Anat Rec (Hoboken); 2019 Sep; 302(9):1571-1579. PubMed ID: 30773850
[TBL] [Abstract][Full Text] [Related]
2. Downregulation of p21-activated kinase-1 inhibits the growth of gastric cancer cells involving cyclin B1.
Liu F; Li X; Wang C; Cai X; Du Z; Xu H; Li F
Int J Cancer; 2009 Dec; 125(11):2511-9. PubMed ID: 19610058
[TBL] [Abstract][Full Text] [Related]
3. GL-1196 Suppresses the Proliferation and Invasion of Gastric Cancer Cells via Targeting PAK4 and Inhibiting PAK4-Mediated Signaling Pathways.
Zhang J; Zhang HY; Wang J; You LH; Zhou RZ; Zhao DM; Cheng MS; Li F
Int J Mol Sci; 2016 Apr; 17(4):470. PubMed ID: 27077843
[TBL] [Abstract][Full Text] [Related]
4. Blockage of PAK1 alleviates the proliferation and invasion of NSCLC cells via inhibiting ERK and AKT signaling activity.
Song P; Song B; Liu J; Wang X; Nan X; Wang J
Clin Transl Oncol; 2021 Apr; 23(4):892-901. PubMed ID: 32974862
[TBL] [Abstract][Full Text] [Related]
5. LCH-7749944, a novel and potent p21-activated kinase 4 inhibitor, suppresses proliferation and invasion in human gastric cancer cells.
Zhang J; Wang J; Guo Q; Wang Y; Zhou Y; Peng H; Cheng M; Zhao D; Li F
Cancer Lett; 2012 Apr; 317(1):24-32. PubMed ID: 22085492
[TBL] [Abstract][Full Text] [Related]
6. Anti-cancer effect of novel PAK1 inhibitor via induction of PUMA-mediated cell death and p21-mediated cell cycle arrest.
Woo TG; Yoon MH; Hong SD; Choi J; Ha NC; Sun H; Park BJ
Oncotarget; 2017 Apr; 8(14):23690-23701. PubMed ID: 28423593
[TBL] [Abstract][Full Text] [Related]
7. PAK1 overexpression promotes cell proliferation in cutaneous T cell lymphoma via suppression of PUMA and p21.
Wang Y; Gu X; Li W; Zhang Q; Zhang C
J Dermatol Sci; 2018 Apr; 90(1):60-67. PubMed ID: 29307600
[TBL] [Abstract][Full Text] [Related]
8. p21-activated protein kinase 1 induces the invasion of gastric cancer cells through c-Jun NH2-terminal kinase-mediated activation of matrix metalloproteinase-2.
Li LH; Wu GY; Lu YZ; Chen XH; Liu BY; Zheng MH; Cai JC
Oncol Rep; 2017 Jul; 38(1):193-200. PubMed ID: 28534988
[TBL] [Abstract][Full Text] [Related]
9. p21-activated kinase 1 determines stem-like phenotype and sunitinib resistance via NF-κB/IL-6 activation in renal cell carcinoma.
Zhu Y; Liu H; Xu L; An H; Liu W; Liu Y; Lin Z; Xu J
Cell Death Dis; 2015 Feb; 6(2):e1637. PubMed ID: 25675297
[TBL] [Abstract][Full Text] [Related]
10. P21-activated kinase 1 stimulates colon cancer cell growth and migration/invasion via ERK- and AKT-dependent pathways.
Huynh N; Liu KH; Baldwin GS; He H
Biochim Biophys Acta; 2010 Sep; 1803(9):1106-13. PubMed ID: 20595063
[TBL] [Abstract][Full Text] [Related]
11. Targeting p21-activated kinase 1 (PAK1) to induce apoptosis of tumor cells.
Ong CC; Jubb AM; Haverty PM; Zhou W; Tran V; Truong T; Turley H; O'Brien T; Vucic D; Harris AL; Belvin M; Friedman LS; Blackwood EM; Koeppen H; Hoeflich KP
Proc Natl Acad Sci U S A; 2011 Apr; 108(17):7177-82. PubMed ID: 21482786
[TBL] [Abstract][Full Text] [Related]
12. Targeting Cdc42 with the small molecule drug AZA197 suppresses primary colon cancer growth and prolongs survival in a preclinical mouse xenograft model by downregulation of PAK1 activity.
Zins K; Gunawardhana S; Lucas T; Abraham D; Aharinejad S
J Transl Med; 2013 Nov; 11():295. PubMed ID: 24279335
[TBL] [Abstract][Full Text] [Related]
13. P21-activated protein kinase 1 is overexpressed in gastric cancer and induces cancer metastasis.
Li LH; Luo Q; Zheng MH; Pan C; Wu GY; Lu YZ; Feng B; Chen XH; Liu BY
Oncol Rep; 2012 May; 27(5):1435-42. PubMed ID: 22293972
[TBL] [Abstract][Full Text] [Related]
14. Effects of p21-activated kinase 1 inhibition on 11q13-amplified ovarian cancer cells.
Prudnikova TY; Villamar-Cruz O; Rawat SJ; Cai KQ; Chernoff J
Oncogene; 2016 Apr; 35(17):2178-85. PubMed ID: 26257058
[TBL] [Abstract][Full Text] [Related]
15. Curcumin suppresses proliferation and invasion in human gastric cancer cells by downregulation of PAK1 activity and cyclin D1 expression.
Cai XZ; Wang J; Li XD; Wang GL; Liu FN; Cheng MS; Li F
Cancer Biol Ther; 2009 Jul; 8(14):1360-8. PubMed ID: 19448398
[TBL] [Abstract][Full Text] [Related]
16. Targeting PKCι-PAK1 signaling pathways in EGFR and KRAS mutant adenocarcinoma and lung squamous cell carcinoma.
Ito M; Codony-Servat C; Codony-Servat J; Lligé D; Chaib I; Sun X; Miao J; Sun R; Cai X; Verlicchi A; Okada M; Molina-Vila MA; Karachaliou N; Cao P; Rosell R
Cell Commun Signal; 2019 Oct; 17(1):137. PubMed ID: 31660987
[TBL] [Abstract][Full Text] [Related]
17. Growth hormone-releasing hormone receptor antagonists inhibit human gastric cancer through downregulation of PAK1-STAT3/NF-κB signaling.
Gan J; Ke X; Jiang J; Dong H; Yao Z; Lin Y; Lin W; Wu X; Yan S; Zhuang Y; Chu WK; Cai R; Zhang X; Cheung HS; Block NL; Pang CP; Schally AV; Zhang H
Proc Natl Acad Sci U S A; 2016 Dec; 113(51):14745-14750. PubMed ID: 27930339
[TBL] [Abstract][Full Text] [Related]
18. Selective killing of gastric cancer cells by a small molecule targeting ROS-mediated ER stress activation.
Zou P; Xia Y; Chen T; Zhang J; Wang Z; Chen W; Chen M; Kanchana K; Yang S; Liang G
Mol Carcinog; 2016 Jun; 55(6):1073-86. PubMed ID: 26086416
[TBL] [Abstract][Full Text] [Related]
19. Design, synthesis and biological evaluation of 1H-pyrazolo [3,4-d]pyrimidine derivatives as PAK1 inhibitors that trigger apoptosis, ER stress and anti-migration effect in MDA-MB-231 cells.
Zhang J; Zou L; Tang P; Pan D; He Z; Yao D
Eur J Med Chem; 2020 May; 194():112220. PubMed ID: 32222676
[TBL] [Abstract][Full Text] [Related]
20. Targeting p21-activated kinase 1 inhibits growth and metastasis via Raf1/MEK1/ERK signaling in esophageal squamous cell carcinoma cells.
Chen L; Bi S; Hou J; Zhao Z; Wang C; Xie S
Cell Commun Signal; 2019 Apr; 17(1):31. PubMed ID: 30971268
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
