BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

303 related articles for article (PubMed ID: 30775971)

  • 1. Cryo-EM structures of the DCPIB-inhibited volume-regulated anion channel LRRC8A in lipid nanodiscs.
    Kern DM; Oh S; Hite RK; Brohawn SG
    Elife; 2019 Feb; 8():. PubMed ID: 30775971
    [TBL] [Abstract][Full Text] [Related]  

  • 2. LRRC8A homohexameric channels poorly recapitulate VRAC regulation and pharmacology.
    Yamada T; Figueroa EE; Denton JS; Strange K
    Am J Physiol Cell Physiol; 2021 Mar; 320(3):C293-C303. PubMed ID: 33356947
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Cryo-EM structures of an LRRC8 chimera with native functional properties reveal heptameric assembly.
    Takahashi H; Yamada T; Denton JS; Strange K; Karakas E
    Elife; 2023 Mar; 12():. PubMed ID: 36897307
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Structural basis for assembly and lipid-mediated gating of LRRC8A:C volume-regulated anion channels.
    Kern DM; Bleier J; Mukherjee S; Hill JM; Kossiakoff AA; Isacoff EY; Brohawn SG
    Nat Struct Mol Biol; 2023 Jun; 30(6):841-852. PubMed ID: 36928458
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Structure of a volume-regulated anion channel of the LRRC8 family.
    Deneka D; Sawicka M; Lam AKM; Paulino C; Dutzler R
    Nature; 2018 Jun; 558(7709):254-259. PubMed ID: 29769723
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Intracellular and extracellular loops of LRRC8 are essential for volume-regulated anion channel function.
    Yamada T; Strange K
    J Gen Physiol; 2018 Jul; 150(7):1003-1015. PubMed ID: 29853476
    [TBL] [Abstract][Full Text] [Related]  

  • 7. The LRRC8 volume-regulated anion channel inhibitor, DCPIB, inhibits mitochondrial respiration independently of the channel.
    Afzal A; Figueroa EE; Kharade SV; Bittman K; Matlock BK; Flaherty DK; Denton JS
    Physiol Rep; 2019 Dec; 7(23):e14303. PubMed ID: 31814333
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Molecular composition and heterogeneity of the LRRC8-containing swelling-activated osmolyte channels in primary rat astrocytes.
    Schober AL; Wilson CS; Mongin AA
    J Physiol; 2017 Nov; 595(22):6939-6951. PubMed ID: 28833202
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Recent Advances in the Structural Biology of the Volume-Regulated Anion Channel LRRC8.
    Kasuya G; Nureki O
    Front Pharmacol; 2022; 13():896532. PubMed ID: 35645818
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Lipid Nanodiscs as a Tool for High-Resolution Structure Determination of Membrane Proteins by Single-Particle Cryo-EM.
    Efremov RG; Gatsogiannis C; Raunser S
    Methods Enzymol; 2017; 594():1-30. PubMed ID: 28779836
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Structural insights into anion selectivity and activation mechanism of LRRC8 volume-regulated anion channels.
    Liu H; Polovitskaya MM; Yang L; Li M; Li H; Han Z; Wu J; Zhang Q; Jentsch TJ; Liao J
    Cell Rep; 2023 Aug; 42(8):112926. PubMed ID: 37543949
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Cryo-EM structures of the human volume-regulated anion channel LRRC8.
    Kasuya G; Nakane T; Yokoyama T; Jia Y; Inoue M; Watanabe K; Nakamura R; Nishizawa T; Kusakizako T; Tsutsumi A; Yanagisawa H; Dohmae N; Hattori M; Ichijo H; Yan Z; Kikkawa M; Shirouzu M; Ishitani R; Nureki O
    Nat Struct Mol Biol; 2018 Sep; 25(9):797-804. PubMed ID: 30127360
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Cryo-EM structure of the volume-regulated anion channel LRRC8D isoform identifies features important for substrate permeation.
    Nakamura R; Numata T; Kasuya G; Yokoyama T; Nishizawa T; Kusakizako T; Kato T; Hagino T; Dohmae N; Inoue M; Watanabe K; Ichijo H; Kikkawa M; Shirouzu M; Jentsch TJ; Ishitani R; Okada Y; Nureki O
    Commun Biol; 2020 May; 3(1):240. PubMed ID: 32415200
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Mechanisms of Activation of LRRC8 Volume Regulated Anion Channels.
    Bertelli S; Remigante A; Zuccolini P; Barbieri R; Ferrera L; Picco C; Gavazzo P; Pusch M
    Cell Physiol Biochem; 2021 Feb; 55(S1):41-56. PubMed ID: 33577730
    [TBL] [Abstract][Full Text] [Related]  

  • 15. LRRC8 Proteins Form Volume-Regulated Anion Channels that Sense Ionic Strength.
    Syeda R; Qiu Z; Dubin AE; Murthy SE; Florendo MN; Mason DE; Mathur J; Cahalan SM; Peters EC; Montal M; Patapoutian A
    Cell; 2016 Jan; 164(3):499-511. PubMed ID: 26824658
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Structure of the human volume regulated anion channel.
    Kefauver JM; Saotome K; Dubin AE; Pallesen J; Cottrell CA; Cahalan SM; Qiu Z; Hong G; Crowley CS; Whitwam T; Lee WH; Ward AB; Patapoutian A
    Elife; 2018 Aug; 7():. PubMed ID: 30095067
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Absolute Protein Amounts and Relative Abundance of Volume-regulated Anion Channel (VRAC) LRRC8 Subunits in Cells and Tissues Revealed by Quantitative Immunoblotting.
    Pervaiz S; Kopp A; von Kleist L; Stauber T
    Int J Mol Sci; 2019 Nov; 20(23):. PubMed ID: 31771171
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Inhibition of gastric H+,K+-ATPase by 4-(2-butyl-6,7-dichloro-2-cyclopentylindan-1-on-5-yl)oxybutyric acid (DCPIB), an inhibitor of volume-regulated anion channel.
    Fujii T; Takahashi Y; Takeshima H; Saitoh C; Shimizu T; Takeguchi N; Sakai H
    Eur J Pharmacol; 2015 Oct; 765():34-41. PubMed ID: 26277321
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Cryo-EM structures of the TMEM16A calcium-activated chloride channel.
    Dang S; Feng S; Tien J; Peters CJ; Bulkley D; Lolicato M; Zhao J; Zuberbühler K; Ye W; Qi L; Chen T; Craik CS; Jan YN; Minor DL; Cheng Y; Jan LY
    Nature; 2017 Dec; 552(7685):426-429. PubMed ID: 29236684
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Molecular Biology and Physiology of Volume-Regulated Anion Channel (VRAC).
    Osei-Owusu J; Yang J; Vitery MDC; Qiu Z
    Curr Top Membr; 2018; 81():177-203. PubMed ID: 30243432
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 16.