These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

267 related articles for article (PubMed ID: 30778053)

  • 1. Engineered transfer RNAs for suppression of premature termination codons.
    Lueck JD; Yoon JS; Perales-Puchalt A; Mackey AL; Infield DT; Behlke MA; Pope MR; Weiner DB; Skach WR; McCray PB; Ahern CA
    Nat Commun; 2019 Feb; 10(1):822. PubMed ID: 30778053
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Identification of the amino acids inserted during suppression of CFTR nonsense mutations and determination of their functional consequences.
    Xue X; Mutyam V; Thakerar A; Mobley J; Bridges RJ; Rowe SM; Keeling KM; Bedwell DM
    Hum Mol Genet; 2017 Aug; 26(16):3116-3129. PubMed ID: 28575328
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Efficient suppression of endogenous CFTR nonsense mutations using anticodon-engineered transfer RNAs.
    Ko W; Porter JJ; Sipple MT; Edwards KM; Lueck JD
    Mol Ther Nucleic Acids; 2022 Jun; 28():685-701. PubMed ID: 35664697
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Therapeutic promise of engineered nonsense suppressor tRNAs.
    Porter JJ; Heil CS; Lueck JD
    Wiley Interdiscip Rev RNA; 2021 Jul; 12(4):e1641. PubMed ID: 33567469
    [TBL] [Abstract][Full Text] [Related]  

  • 5. The effect of premature termination codon mutations on CFTR mRNA abundance in human nasal epithelium and intestinal organoids: a basis for read-through therapies in cystic fibrosis.
    Clarke LA; Awatade NT; Felício VM; Silva IA; Calucho M; Pereira L; Azevedo P; Cavaco J; Barreto C; Bertuzzo C; Gartner S; Beekman J; Amaral MD
    Hum Mutat; 2019 Mar; 40(3):326-334. PubMed ID: 30488522
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Suppression of premature termination codons as a therapeutic approach.
    Keeling KM; Wang D; Conard SE; Bedwell DM
    Crit Rev Biochem Mol Biol; 2012 Sep; 47(5):444-63. PubMed ID: 22672057
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Ataluren stimulates ribosomal selection of near-cognate tRNAs to promote nonsense suppression.
    Roy B; Friesen WJ; Tomizawa Y; Leszyk JD; Zhuo J; Johnson B; Dakka J; Trotta CR; Xue X; Mutyam V; Keeling KM; Mobley JA; Rowe SM; Bedwell DM; Welch EM; Jacobson A
    Proc Natl Acad Sci U S A; 2016 Nov; 113(44):12508-12513. PubMed ID: 27702906
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Correction of mutations within the cystic fibrosis transmembrane conductance regulator by site-directed RNA editing.
    Montiel-Gonzalez MF; Vallecillo-Viejo I; Yudowski GA; Rosenthal JJ
    Proc Natl Acad Sci U S A; 2013 Nov; 110(45):18285-90. PubMed ID: 24108353
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Discovery of Clinically Approved Agents That Promote Suppression of Cystic Fibrosis Transmembrane Conductance Regulator Nonsense Mutations.
    Mutyam V; Du M; Xue X; Keeling KM; White EL; Bostwick JR; Rasmussen L; Liu B; Mazur M; Hong JS; Falk Libby E; Liang F; Shang H; Mense M; Suto MJ; Bedwell DM; Rowe SM
    Am J Respir Crit Care Med; 2016 Nov; 194(9):1092-1103. PubMed ID: 27104944
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Positional effects of premature termination codons on the biochemical and biophysical properties of CFTR.
    Yeh JT; Hwang TC
    J Physiol; 2020 Feb; 598(3):517-541. PubMed ID: 31585024
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Tobramycin is a suppressor of premature termination codons.
    Altamura N; Castaldo R; Finotti A; Breveglieri G; Salvatori F; Zuccato C; Gambari R; Panin GC; Borgatti M
    J Cyst Fibros; 2013 Dec; 12(6):806-11. PubMed ID: 23540394
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Synthetic aminoglycosides efficiently suppress cystic fibrosis transmembrane conductance regulator nonsense mutations and are enhanced by ivacaftor.
    Xue X; Mutyam V; Tang L; Biswas S; Du M; Jackson LA; Dai Y; Belakhov V; Shalev M; Chen F; Schacht J; J Bridges R; Baasov T; Hong J; Bedwell DM; Rowe SM
    Am J Respir Cell Mol Biol; 2014 Apr; 50(4):805-16. PubMed ID: 24251786
    [TBL] [Abstract][Full Text] [Related]  

  • 13. The suppression of premature termination codons and the repair of splicing mutations in CFTR.
    Oren YS; Pranke IM; Kerem B; Sermet-Gaudelus I
    Curr Opin Pharmacol; 2017 Jun; 34():125-131. PubMed ID: 29128743
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Toward a rationale for the PTC124 (Ataluren) promoted readthrough of premature stop codons: a computational approach and GFP-reporter cell-based assay.
    Lentini L; Melfi R; Di Leonardo A; Spinello A; Barone G; Pace A; Palumbo Piccionello A; Pibiri I
    Mol Pharm; 2014 Mar; 11(3):653-64. PubMed ID: 24483936
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Investigating REPAIRv2 as a Tool to Edit
    Melfi R; Cancemi P; Chiavetta R; Barra V; Lentini L; Di Leonardo A
    Int J Mol Sci; 2020 Jul; 21(13):. PubMed ID: 32640650
    [TBL] [Abstract][Full Text] [Related]  

  • 16. A small molecule that induces translational readthrough of CFTR nonsense mutations by eRF1 depletion.
    Sharma J; Du M; Wong E; Mutyam V; Li Y; Chen J; Wangen J; Thrasher K; Fu L; Peng N; Tang L; Liu K; Mathew B; Bostwick RJ; Augelli-Szafran CE; Bihler H; Liang F; Mahiou J; Saltz J; Rab A; Hong J; Sorscher EJ; Mendenhall EM; Coppola CJ; Keeling KM; Green R; Mense M; Suto MJ; Rowe SM; Bedwell DM
    Nat Commun; 2021 Jul; 12(1):4358. PubMed ID: 34272367
    [TBL] [Abstract][Full Text] [Related]  

  • 17. U6 promoter-enhanced GlnUAG suppressor tRNA has higher suppression efficacy and can be stably expressed in 293 cells.
    Koukuntla R; Ramsey WJ; Young WB; Link CJ
    J Gene Med; 2013 Feb; 15(2):93-101. PubMed ID: 23303531
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Pharmaceuticals targeting nonsense mutations in genetic diseases: progress in development.
    Rowe SM; Clancy JP
    BioDrugs; 2009; 23(3):165-74. PubMed ID: 19627168
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Targeting Nonsense: Optimization of 1,2,4-Oxadiazole TRIDs to Rescue CFTR Expression and Functionality in Cystic Fibrosis Cell Model Systems.
    Pibiri I; Melfi R; Tutone M; Di Leonardo A; Pace A; Lentini L
    Int J Mol Sci; 2020 Sep; 21(17):. PubMed ID: 32899265
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Functional Restoration of CFTR Nonsense Mutations in Intestinal Organoids.
    de Poel E; Spelier S; Suen SWF; Kruisselbrink E; Graeber SY; Mall MA; Weersink EJM; van der Eerden MM; Koppelman GH; van der Ent CK; Beekman JM
    J Cyst Fibros; 2022 Mar; 21(2):246-253. PubMed ID: 34666947
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 14.