167 related articles for article (PubMed ID: 30780018)
1. Discovery of alkoxy benzamide derivatives as novel BPTF bromodomain inhibitors via structure-based virtual screening.
Zhang D; Han J; Lu W; Lian F; Wang J; Lu T; Tao H; Xiao S; Zhang F; Liu YC; Liu R; Zhang N; Jiang H; Chen K; Zhao C; Luo C
Bioorg Chem; 2019 May; 86():494-500. PubMed ID: 30780018
[TBL] [Abstract][Full Text] [Related]
2. Discovery of new small molecule inhibitors of the BPTF bromodomain.
Liang X; Cao Y; Duan Z; Wang M; Zhang N; Ding Y; Luo C; Lu N; Chen S
Bioorg Chem; 2023 May; 134():106453. PubMed ID: 36898211
[TBL] [Abstract][Full Text] [Related]
3. Discovery of selective BPTF bromodomain inhibitors by screening and structure-based optimization.
Xiong L; Mao X; Guo Y; Zhou Y; Chen M; Chen P; Yang S; Li L
Biochem Biophys Res Commun; 2021 Mar; 545():125-131. PubMed ID: 33548625
[TBL] [Abstract][Full Text] [Related]
4. New inhibitors for the BPTF bromodomain enabled by structural biology and biophysical assay development.
Ycas PD; Zahid H; Chan A; Olson NM; Johnson JA; Talluri SK; Schonbrunn E; Pomerantz WCK
Org Biomol Chem; 2020 Jul; 18(27):5174-5182. PubMed ID: 32588860
[TBL] [Abstract][Full Text] [Related]
5. Synthesis of NVS-BPTF-1 and evaluation of its biological activity.
Mélin L; Calosing C; Kharenko OA; Hansen HC; Gagnon A
Bioorg Med Chem Lett; 2021 Sep; 47():128208. PubMed ID: 34146702
[TBL] [Abstract][Full Text] [Related]
6. Compound C620-0696, a new potent inhibitor targeting BPTF, the chromatin-remodeling factor in non-small-cell lung cancer.
Xu J; Wang Q; Leung ELH; Li Y; Fan X; Wu Q; Yao X; Liu L
Front Med; 2020 Feb; 14(1):60-67. PubMed ID: 31104301
[TBL] [Abstract][Full Text] [Related]
7. Discovery of High-Affinity Inhibitors of the BPTF Bromodomain.
Lu T; Lu H; Duan Z; Wang J; Han J; Xiao S; Chen H; Jiang H; Chen Y; Yang F; Li Q; Chen D; Lin J; Li B; Jiang H; Chen K; Lu W; Lin H; Luo C
J Med Chem; 2021 Aug; 64(16):12075-12088. PubMed ID: 34375106
[TBL] [Abstract][Full Text] [Related]
8. New Design Rules for Developing Potent Cell-Active Inhibitors of the Nucleosome Remodeling Factor (NURF) via BPTF Bromodomain Inhibition.
Zahid H; Buchholz CR; Singh M; Ciccone MF; Chan A; Nithianantham S; Shi K; Aihara H; Fischer M; Schönbrunn E; Dos Santos CO; Landry JW; Pomerantz WCK
J Med Chem; 2021 Sep; 64(18):13902-13917. PubMed ID: 34515477
[TBL] [Abstract][Full Text] [Related]
9. Selectivity, ligand deconstruction, and cellular activity analysis of a BPTF bromodomain inhibitor.
Kirberger SE; Ycas PD; Johnson JA; Chen C; Ciccone MF; Woo RWL; Urick AK; Zahid H; Shi K; Aihara H; McAllister SD; Kashani-Sabet M; Shi J; Dickson A; Dos Santos CO; Pomerantz WCK
Org Biomol Chem; 2019 Feb; 17(7):2020-2027. PubMed ID: 30706071
[TBL] [Abstract][Full Text] [Related]
10. Specific Acetylation Patterns of H2A.Z Form Transient Interactions with the BPTF Bromodomain.
Perell GT; Mishra NK; Sudhamalla B; Ycas PD; Islam K; Pomerantz WCK
Biochemistry; 2017 Sep; 56(35):4607-4615. PubMed ID: 28771339
[TBL] [Abstract][Full Text] [Related]
11. Molecular docking and dynamics simulation study of flavonoids as BET bromodomain inhibitors.
Raj U; Kumar H; Varadwaj PK
J Biomol Struct Dyn; 2017 Aug; 35(11):2351-2362. PubMed ID: 27494802
[TBL] [Abstract][Full Text] [Related]
12. Opportunity knocks for uncovering the new function of an understudied nucleosome remodeling complex member, the bromodomain PHD finger transcription factor, BPTF.
Zahid H; Olson NM; Pomerantz WCK
Curr Opin Chem Biol; 2021 Aug; 63():57-67. PubMed ID: 33706239
[TBL] [Abstract][Full Text] [Related]
13. Importance of a crystalline water network in docking-based virtual screening: a case study of BRD4.
Zhong H; Wang Z; Wang X; Liu H; Li D; Liu H; Yao X; Hou T
Phys Chem Chem Phys; 2019 Dec; 21(45):25276-25289. PubMed ID: 31701109
[TBL] [Abstract][Full Text] [Related]
14. Structure-guided discovery of a novel, potent, and orally bioavailable 3,5-dimethylisoxazole aryl-benzimidazole BET bromodomain inhibitor.
Sperandio D; Aktoudianakis V; Babaoglu K; Chen X; Elbel K; Chin G; Corkey B; Du J; Jiang B; Kobayashi T; Mackman R; Martinez R; Yang H; Zablocki J; Kusam S; Jordan K; Webb H; Bates JG; Lad L; Mish M; Niedziela-Majka A; Metobo S; Sapre A; Hung M; Jin D; Fung W; Kan E; Eisenberg G; Larson N; Newby ZER; Lansdon E; Tay C; Neve RM; Shevick SL; Breckenridge DG
Bioorg Med Chem; 2019 Feb; 27(3):457-469. PubMed ID: 30606676
[TBL] [Abstract][Full Text] [Related]
15. Discovery of Benzo[cd]indol-2(1H)-ones as Potent and Specific BET Bromodomain Inhibitors: Structure-Based Virtual Screening, Optimization, and Biological Evaluation.
Xue X; Zhang Y; Liu Z; Song M; Xing Y; Xiang Q; Wang Z; Tu Z; Zhou Y; Ding K; Xu Y
J Med Chem; 2016 Feb; 59(4):1565-79. PubMed ID: 26731490
[TBL] [Abstract][Full Text] [Related]
16. Molecular basis for site-specific read-out of histone H3K4me3 by the BPTF PHD finger of NURF.
Li H; Ilin S; Wang W; Duncan EM; Wysocka J; Allis CD; Patel DJ
Nature; 2006 Jul; 442(7098):91-5. PubMed ID: 16728978
[TBL] [Abstract][Full Text] [Related]
17. Discovery of a Chemical Probe to Study Implications of BPTF Bromodomain Inhibition in Cellular and in vivo Experiments.
Martinelli P; Schaaf O; Mantoulidis A; Martin LJ; Fuchs JE; Bader G; Gollner A; Wolkerstorfer B; Rogers C; Balıkçı E; Lipp JJ; Mischerikow N; Doebel S; Gerstberger T; Sommergruber W; Huber KVM; Böttcher J
ChemMedChem; 2023 Mar; 18(6):e202200686. PubMed ID: 36649575
[TBL] [Abstract][Full Text] [Related]
18. Exploiting the 7-methylimidazo[1,5-a]pyrazin-8(7H)-one scaffold for the development of novel chemical inhibitors for Bromodomain and Extraterminal Domain (BET) family.
Yang Y; Chen P; Zhao L; Zhang F; Zhang B; Xu C; Zhang H; Zhou J
Bioorg Chem; 2019 Sep; 90():103044. PubMed ID: 31220668
[TBL] [Abstract][Full Text] [Related]
19. Dual Screening of BPTF and Brd4 Using Protein-Observed Fluorine NMR Uncovers New Bromodomain Probe Molecules.
Urick AK; Hawk LM; Cassel MK; Mishra NK; Liu S; Adhikari N; Zhang W; dos Santos CO; Hall JL; Pomerantz WC
ACS Chem Biol; 2015 Oct; 10(10):2246-56. PubMed ID: 26158404
[TBL] [Abstract][Full Text] [Related]
20. The exploitation of FRET probes to track bromodomain/histone interactions in cells for bromodomain inhibitors.
Sasaki K; Yoshida M
Drug Discov Today Technol; 2016 Mar; 19():51-56. PubMed ID: 27769358
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]