BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

186 related articles for article (PubMed ID: 30789758)

  • 1. Synthesis and evaluation of novel 7
    Liu YM; Chen CH; Yeh TK; Liou JP
    Future Med Chem; 2019 May; 11(9):959-974. PubMed ID: 30789758
    [No Abstract]   [Full Text] [Related]  

  • 2. Cytotoxic and Apoptotic Effects of Novel Pyrrolo[2,3-d]Pyrimidine Derivatives Containing Urea Moieties on Cancer Cell Lines.
    Kilic-Kurt Z; Bakar-Ates F; Karakas B; Kütük Ö
    Anticancer Agents Med Chem; 2018; 18(9):1303-1312. PubMed ID: 29866023
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Synthesis and antiproliferative activity of 2,4-disubstituted 6-aryl-7H-pyrrolo[3,2-d]pyrimidin-7-one 5-oxides.
    Pudziuvelyte E; Ríos-Luci C; León LG; Cikotiene I; Padrón JM
    Bioorg Med Chem; 2009 Jul; 17(14):4955-60. PubMed ID: 19527934
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Synthesis, anticancer activity and effects on cell cycle profile and apoptosis of novel thieno[2,3-d]pyrimidine and thieno[3,2-e] triazolo[4,3-c]pyrimidine derivatives.
    Kandeel MM; Refaat HM; Kassab AE; Shahin IG; Abdelghany TM
    Eur J Med Chem; 2015 Jan; 90():620-32. PubMed ID: 25499930
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Synthesis of pyrrolo[2,3-d]pyrimidine derivatives and their antiproliferative activity against melanoma cell line.
    Jung MH; Kim H; Choi WK; El-Gamal MI; Park JH; Yoo KH; Sim TB; Lee SH; Baek D; Hah JM; Cho JH; Oh CH
    Bioorg Med Chem Lett; 2009 Dec; 19(23):6538-43. PubMed ID: 19857963
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Discovery of 7H-pyrrolo[2,3-d]pyridine derivatives as potent FAK inhibitors: Design, synthesis, biological evaluation and molecular docking study.
    Wang R; Zhao X; Yu S; Chen Y; Cui H; Wu T; Hao C; Zhao D; Cheng M
    Bioorg Chem; 2020 Sep; 102():104092. PubMed ID: 32707280
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Design, synthesis, and biological evaluation of 2,6,7-substituted pyrrolo[2,3-d]pyrimidines as cyclin dependent kinase inhibitor in pancreatic cancer cells.
    Shi X; Quan Y; Wang Y; Wang Y; Li Y
    Bioorg Med Chem Lett; 2021 Feb; 33():127725. PubMed ID: 33316409
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Discovery of novel pyrrolo-pyridine/pyrimidine derivatives bearing pyridazinone moiety as c-Met kinase inhibitors.
    Wang LX; Liu X; Xu S; Tang Q; Duan Y; Xiao Z; Zhi J; Jiang L; Zheng P; Zhu W
    Eur J Med Chem; 2017 Dec; 141():538-551. PubMed ID: 29107421
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Molecular Dynamics and Biological Evaluation of 2-chloro-7-cyclopentyl- 7H-pyrrolo[2,3-d]pyrimidine Derivatives Against Breast Cancer.
    Singaram K; Marimuthu D; Baskaran S; Chinaga SK; Shanmugarajan D; Vadivel T
    Comb Chem High Throughput Screen; 2017; 20(8):703-712. PubMed ID: 28738766
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Design, synthesis and biological evaluation of novel 6-substituted pyrrolo [3,2-d] pyrimidine analogues as antifolate antitumor agents.
    Tian C; Wang M; Han Z; Fang F; Zhang Z; Wang X; Liu J
    Eur J Med Chem; 2017 Sep; 138():630-643. PubMed ID: 28711701
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Synthesis and antitumor activity of a novel series of 6-substituted pyrrolo[2,3-d]pyrimidines as potential nonclassical antifolates targeting both thymidylate and purine nucleotide biosynthesis.
    Liu Y; Zhang C; Zhang H; Li M; Yuan J; Zhang Y; Zhou J; Guo H; Zhao L; Du Y; Wang L; Ren L
    Eur J Med Chem; 2015 Mar; 93():142-55. PubMed ID: 25668494
    [TBL] [Abstract][Full Text] [Related]  

  • 12. CK1δ as a potential therapeutic target to treat bladder cancer.
    Lin YC; Chen MC; Hsieh TH; Liou JP; Chen CH
    Aging (Albany NY); 2020 Apr; 12(7):5764-5780. PubMed ID: 32282334
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Novel water-soluble substituted pyrrolo[3,2-d]pyrimidines: design, synthesis, and biological evaluation as antitubulin antitumor agents.
    Gangjee A; Pavana RK; Li W; Hamel E; Westbrook C; Mooberry SL
    Pharm Res; 2012 Nov; 29(11):3033-9. PubMed ID: 22814902
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Synthesis and in vitro antiproliferative activity of C5-benzyl substituted 2-amino-pyrrolo[2,3-d]pyrimidines as potent Hsp90 inhibitors.
    Lee JH; Shin SC; Seo SH; Seo YH; Jeong N; Kim CW; Kim EE; Keum G
    Bioorg Med Chem Lett; 2017 Jan; 27(2):237-241. PubMed ID: 27914802
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Targeting dihydrofolate reductase: Design, synthesis and biological evaluation of novel 6-substituted pyrrolo[2,3-d]pyrimidines as nonclassical antifolates and as potential antitumor agents.
    Gao T; Zhang C; Shi X; Guo R; Zhang K; Gu J; Li L; Li S; Zheng Q; Cui M; Cui M; Gao X; Liu Y; Wang L
    Eur J Med Chem; 2019 Sep; 178():329-340. PubMed ID: 31200235
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Discovery of pyrrolo[2,3-d]pyrimidine derivatives as potent Axl inhibitors: Design, synthesis and biological evaluation.
    Xu D; Sun D; Wang W; Peng X; Zhan Z; Ji Y; Shen Y; Geng M; Ai J; Duan W
    Eur J Med Chem; 2021 Aug; 220():113497. PubMed ID: 33957388
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Novel 6-substituted benzoyl and non-benzoyl straight chain pyrrolo[2,3-d]pyrimidines as potential antitumor agents with multitargeted inhibition of TS, GARFTase and AICARFTase.
    Xing R; Zhang H; Yuan J; Zhang K; Li L; Guo H; Zhao L; Zhang C; Li S; Gao T; Liu Y; Wang L
    Eur J Med Chem; 2017 Oct; 139():531-541. PubMed ID: 28830032
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Structural and Biological Investigations for a Series of N-5 Substituted Pyrrolo[3,2-
    Cawrse BM; Robinson NM; Lee NC; Wilson GM; Seley-Radtke KL
    Molecules; 2019 Jul; 24(14):. PubMed ID: 31340431
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Antiproliferative activities of halogenated pyrrolo[3,2-d]pyrimidines.
    Temburnikar KW; Ross CR; Wilson GM; Balzarini J; Cawrse BM; Seley-Radtke KL
    Bioorg Med Chem; 2015 Aug; 23(15):4354-4363. PubMed ID: 26122770
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Novel 5,6-disubstituted pyrrolo[2,3-d]pyrimidine derivatives as broad spectrum antiproliferative agents: Synthesis, cell based assays, kinase profile and molecular docking study.
    Lee JH; El-Damasy AK; Seo SH; Gadhe CG; Pae AN; Jeong N; Hong SS; Keum G
    Bioorg Med Chem; 2018 Nov; 26(21):5596-5611. PubMed ID: 30385226
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.