These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

146 related articles for article (PubMed ID: 30790465)

  • 1. Structure-Activity Relationship Studies of the Natural Product G
    Xiong XF; Zhang H; Boesgaard MW; Underwood CR; Bräuner-Osborne H; Strømgaard K
    ChemMedChem; 2019 Apr; 14(8):865-870. PubMed ID: 30790465
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Total synthesis and structure-activity relationship studies of a series of selective G protein inhibitors.
    Xiong XF; Zhang H; Underwood CR; Harpsøe K; Gardella TJ; Wöldike MF; Mannstadt M; Gloriam DE; Bräuner-Osborne H; Strømgaard K
    Nat Chem; 2016 Nov; 8(11):1035-1041. PubMed ID: 27768111
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Structure-Activity Relationship Studies of the Cyclic Depsipeptide Natural Product YM-254890, Targeting the G
    Zhang H; Xiong XF; Boesgaard MW; Underwood CR; Bräuner-Osborne H; Strømgaard K
    ChemMedChem; 2017 Jun; 12(11):830-834. PubMed ID: 28509439
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Structure-activity relationship and conformational studies of the natural product cyclic depsipeptides YM-254890 and FR900359.
    Zhang H; Nielsen AL; Boesgaard MW; Harpsøe K; Daly NL; Xiong XF; Underwood CR; Haugaard-Kedström LM; Bräuner-Osborne H; Gloriam DE; Strømgaard K
    Eur J Med Chem; 2018 Aug; 156():847-860. PubMed ID: 30055466
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Delineation of molecular determinants for FR900359 inhibition of G
    Boesgaard MW; Harpsøe K; Malmberg M; Underwood CR; Inoue A; Mathiesen JM; König GM; Kostenis E; Gloriam DE; Bräuner-Osborne H
    J Biol Chem; 2020 Oct; 295(40):13850-13861. PubMed ID: 32753482
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Functional evidence for biased inhibition of G protein signaling by YM-254890 in human coronary artery endothelial cells.
    Peng Q; Alqahtani S; Nasrullah MZA; Shen J
    Eur J Pharmacol; 2021 Jan; 891():173706. PubMed ID: 33152337
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Deciphering Specificity Determinants for FR900359-Derived G
    Reher R; Kühl T; Annala S; Benkel T; Kaufmann D; Nubbemeyer B; Odhiambo JP; Heimer P; Bäuml CA; Kehraus S; Crüsemann M; Kostenis E; Tietze D; König GM; Imhof D
    ChemMedChem; 2018 Aug; 13(16):1634-1643. PubMed ID: 29873888
    [TBL] [Abstract][Full Text] [Related]  

  • 8. A novel Galphaq/11-selective inhibitor.
    Takasaki J; Saito T; Taniguchi M; Kawasaki T; Moritani Y; Hayashi K; Kobori M
    J Biol Chem; 2004 Nov; 279(46):47438-45. PubMed ID: 15339913
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Anti-hypertensive mechanisms of cyclic depsipeptide inhibitor ligands for G
    Meleka MM; Edwards AJ; Xia J; Dahlen SA; Mohanty I; Medcalf M; Aggarwal S; Moeller KD; Mortensen OV; Osei-Owusu P
    Pharmacol Res; 2019 Mar; 141():264-275. PubMed ID: 30634050
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Applying Molecular Networking for the Detection of Natural Sources and Analogues of the Selective Gq Protein Inhibitor FR900359.
    Reher R; Kuschak M; Heycke N; Annala S; Kehraus S; Dai HF; Müller CE; Kostenis E; König GM; Crüsemann M
    J Nat Prod; 2018 Jul; 81(7):1628-1635. PubMed ID: 29943987
    [TBL] [Abstract][Full Text] [Related]  

  • 11. YM-254890 analogues, novel cyclic depsipeptides with Galpha(q/11) inhibitory activity from Chromobacterium sp. QS3666.
    Taniguchi M; Suzumura K; Nagai K; Kawasaki T; Takasaki J; Sekiguchi M; Moritani Y; Saito T; Hayashi K; Fujita S; Tsukamoto S; Suzuki K
    Bioorg Med Chem; 2004 Jun; 12(12):3125-33. PubMed ID: 15158780
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Recent achievements in developing selective G
    Zhang H; Nielsen AL; Strømgaard K
    Med Res Rev; 2020 Jan; 40(1):135-157. PubMed ID: 31218731
    [TBL] [Abstract][Full Text] [Related]  

  • 13. The chromodepsins - chemistry, biology and biosynthesis of a selective Gq inhibitor natural product family.
    Hermes C; König GM; Crüsemann M
    Nat Prod Rep; 2021 Dec; 38(12):2276-2292. PubMed ID: 33998635
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Rational design of a heterotrimeric G protein α subunit with artificial inhibitor sensitivity.
    Malfacini D; Patt J; Annala S; Harpsøe K; Eryilmaz F; Reher R; Crüsemann M; Hanke W; Zhang H; Tietze D; Gloriam DE; Bräuner-Osborne H; Strømgaard K; König GM; Inoue A; Gomeza J; Kostenis E
    J Biol Chem; 2019 Apr; 294(15):5747-5758. PubMed ID: 30745359
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Unraveling binding mechanism and kinetics of macrocyclic Gα
    Voss JH; Nagel J; Rafehi M; Guixà-González R; Malfacini D; Patt J; Kehraus S; Inoue A; König GM; Kostenis E; Deupi X; Namasivayam V; Müller CE
    Pharmacol Res; 2021 Nov; 173():105880. PubMed ID: 34506902
    [TBL] [Abstract][Full Text] [Related]  

  • 16. An experimental strategy to probe Gq contribution to signal transduction in living cells.
    Patt J; Alenfelder J; Pfeil EM; Voss JH; Merten N; Eryilmaz F; Heycke N; Rick U; Inoue A; Kehraus S; Deupi X; Müller CE; König GM; Crüsemann M; Kostenis E
    J Biol Chem; 2021; 296():100472. PubMed ID: 33639168
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Structural basis for the specific inhibition of heterotrimeric Gq protein by a small molecule.
    Nishimura A; Kitano K; Takasaki J; Taniguchi M; Mizuno N; Tago K; Hakoshima T; Itoh H
    Proc Natl Acad Sci U S A; 2010 Aug; 107(31):13666-71. PubMed ID: 20639466
    [TBL] [Abstract][Full Text] [Related]  

  • 18. On the selectivity of the Gαq inhibitor UBO-QIC: A comparison with the Gαi inhibitor pertussis toxin.
    Gao ZG; Jacobson KA
    Biochem Pharmacol; 2016 May; 107():59-66. PubMed ID: 26954502
    [TBL] [Abstract][Full Text] [Related]  

  • 19. In Vitro Module Editing Of NRPS Enables Production Of Highly Potent G
    Hashimoto T; Suenaga H; Amagai K; Hashimoto J; Kozone I; Takahashi S; Shin-Ya K
    Angew Chem Int Ed Engl; 2024 Mar; 63(10):e202317805. PubMed ID: 38238265
    [TBL] [Abstract][Full Text] [Related]  

  • 20. G-protein inhibition profile of the reported Gq/11 inhibitor UBO-QIC.
    Kukkonen JP
    Biochem Biophys Res Commun; 2016 Jan; 469(1):101-107. PubMed ID: 26614908
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.