BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

952 related articles for article (PubMed ID: 30794926)

  • 21. Vascular endothelial growth factor (VEGF) and VEGF receptor inhibitors in the treatment of renal cell carcinomas.
    Roskoski R
    Pharmacol Res; 2017 Jun; 120():116-132. PubMed ID: 28330784
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Aberrant extracellular signal-regulated kinase (ERK)1/2 signalling in suicide brain: role of ERK kinase 1 (MEK1).
    Dwivedi Y; Rizavi HS; Zhang H; Roberts RC; Conley RR; Pandey GN
    Int J Neuropsychopharmacol; 2009 Nov; 12(10):1337-54. PubMed ID: 19835659
    [TBL] [Abstract][Full Text] [Related]  

  • 23. MEK1/2 inhibitors in the treatment of gynecologic malignancies.
    Miller CR; Oliver KE; Farley JH
    Gynecol Oncol; 2014 Apr; 133(1):128-37. PubMed ID: 24434059
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Stamping out RAF and MEK1/2 to inhibit the ERK1/2 pathway: an emerging threat to anticancer therapy.
    Mandal R; Becker S; Strebhardt K
    Oncogene; 2016 May; 35(20):2547-61. PubMed ID: 26364606
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Oncogenic tyrosine kinase NPM/ALK induces activation of the MEK/ERK signaling pathway independently of c-Raf.
    Marzec M; Kasprzycka M; Liu X; Raghunath PN; Wlodarski P; Wasik MA
    Oncogene; 2007 Feb; 26(6):813-21. PubMed ID: 16909118
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Investigation of the Mek-MAP kinase-Rsk pathway in human breast cancer.
    Salh B; Marotta A; Matthewson C; Ahluwalia M; Flint J; Owen D; Pelech S
    Anticancer Res; 1999; 19(1B):731-40. PubMed ID: 10216485
    [TBL] [Abstract][Full Text] [Related]  

  • 27. MEK1 and the extracellular signal-regulated kinases are required for the stimulation of IL-2 gene transcription in T cells.
    Whitehurst CE; Geppert TD
    J Immunol; 1996 Feb; 156(3):1020-9. PubMed ID: 8557975
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Variable apoptotic response of NSCLC cells to inhibition of the MEK/ERK pathway by small molecules or dominant negative mutants.
    Brognard J; Dennis PA
    Cell Death Differ; 2002 Sep; 9(9):893-904. PubMed ID: 12181740
    [TBL] [Abstract][Full Text] [Related]  

  • 29. A Raf-induced allosteric transition of KSR stimulates phosphorylation of MEK.
    Brennan DF; Dar AC; Hertz NT; Chao WC; Burlingame AL; Shokat KM; Barford D
    Nature; 2011 Apr; 472(7343):366-9. PubMed ID: 21441910
    [TBL] [Abstract][Full Text] [Related]  

  • 30. PAK1 primes MEK1 for phosphorylation by Raf-1 kinase during cross-cascade activation of the ERK pathway.
    Coles LC; Shaw PE
    Oncogene; 2002 Mar; 21(14):2236-44. PubMed ID: 11948406
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Tumour cell responses to MEK1/2 inhibitors: acquired resistance and pathway remodelling.
    Little AS; Balmanno K; Sale MJ; Smith PD; Cook SJ
    Biochem Soc Trans; 2012 Feb; 40(1):73-8. PubMed ID: 22260668
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Positive regulation of Raf1-MEK1/2-ERK1/2 signaling by protein serine/threonine phosphatase 2A holoenzymes.
    Adams DG; Coffee RL; Zhang H; Pelech S; Strack S; Wadzinski BE
    J Biol Chem; 2005 Dec; 280(52):42644-54. PubMed ID: 16239230
    [TBL] [Abstract][Full Text] [Related]  

  • 33. The 96 kDa protein kinase activated by oncogenic Ras in Xenopus egg extracts is also activated by constitutively active Mek: activation requires serine/threonine phosphorylation.
    Pan BT; Zhang Y; Brott B; Chen DH
    Oncogene; 1997 Apr; 14(14):1653-60. PubMed ID: 9135066
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Flagellin and lipopolysaccharide stimulate the MEK-ERK signaling pathway in chicken heterophils through differential activation of the small GTPases, Ras and Rap1.
    Kogut MH; Genovese KJ; He H
    Mol Immunol; 2007 Mar; 44(7):1729-36. PubMed ID: 17045653
    [TBL] [Abstract][Full Text] [Related]  

  • 35. RAF protein-serine/threonine kinases: structure and regulation.
    Roskoski R
    Biochem Biophys Res Commun; 2010 Aug; 399(3):313-7. PubMed ID: 20674547
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Opposite long-term regulation of c-Myc and p27Kip1 through overactivation of Raf-1 and the MEK/ERK module in proliferating human choroidal melanoma cells.
    Lefevre G; Calipel A; Mouriaux F; Hecquet C; Malecaze F; Mascarelli F
    Oncogene; 2003 Dec; 22(55):8813-22. PubMed ID: 14654778
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Mathematical modelling unveils the essential role of cellular phosphatases in the inhibition of RAF-MEK-ERK signalling by sorafenib in hepatocellular carcinoma cells.
    Saidak Z; Giacobbi AS; Louandre C; Sauzay C; Mammeri Y; Galmiche A
    Cancer Lett; 2017 Apr; 392():1-8. PubMed ID: 28161506
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Elevated urokinase-type plasminogen activator receptor expression in a colon cancer cell line is due to a constitutively activated extracellular signal-regulated kinase-1-dependent signaling cascade.
    Lengyel E; Wang H; Gum R; Simon C; Wang Y; Boyd D
    Oncogene; 1997 May; 14(21):2563-73. PubMed ID: 9191056
    [TBL] [Abstract][Full Text] [Related]  

  • 39. IQGAP1 scaffold-kinase interaction blockade selectively targets RAS-MAP kinase-driven tumors.
    Jameson KL; Mazur PK; Zehnder AM; Zhang J; Zarnegar B; Sage J; Khavari PA
    Nat Med; 2013 May; 19(5):626-630. PubMed ID: 23603816
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Biological Rationale for Targeting MEK/ERK Pathways in Anti-Cancer Therapy and to Potentiate Tumour Responses to Radiation.
    Marampon F; Ciccarelli C; Zani BM
    Int J Mol Sci; 2019 May; 20(10):. PubMed ID: 31126017
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 48.