BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

772 related articles for article (PubMed ID: 30799198)

  • 1. Oxidized ATM-mediated glycolysis enhancement in breast cancer-associated fibroblasts contributes to tumor invasion through lactate as metabolic coupling.
    Sun K; Tang S; Hou Y; Xi L; Chen Y; Yin J; Peng M; Zhao M; Cui X; Liu M
    EBioMedicine; 2019 Mar; 41():370-383. PubMed ID: 30799198
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Oxidized ATM promotes abnormal proliferation of breast CAFs through maintaining intracellular redox homeostasis and activating the PI3K-AKT, MEK-ERK, and Wnt-β-catenin signaling pathways.
    Tang S; Hou Y; Zhang H; Tu G; Yang L; Sun Y; Lang L; Tang X; Du YE; Zhou M; Yu T; Xu L; Wen S; Liu C; Liu M
    Cell Cycle; 2015; 14(12):1908-24. PubMed ID: 25970706
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Reciprocal metabolic reprogramming through lactate shuttle coordinately influences tumor-stroma interplay.
    Fiaschi T; Marini A; Giannoni E; Taddei ML; Gandellini P; De Donatis A; Lanciotti M; Serni S; Cirri P; Chiarugi P
    Cancer Res; 2012 Oct; 72(19):5130-40. PubMed ID: 22850421
    [TBL] [Abstract][Full Text] [Related]  

  • 4. The antioxidant uncoupling protein 2 stimulates hnRNPA2/B1, GLUT1 and PKM2 expression and sensitizes pancreas cancer cells to glycolysis inhibition.
    Brandi J; Cecconi D; Cordani M; Torrens-Mas M; Pacchiana R; Dalla Pozza E; Butera G; Manfredi M; Marengo E; Oliver J; Roca P; Dando I; Donadelli M
    Free Radic Biol Med; 2016 Dec; 101():305-316. PubMed ID: 27989750
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Hypoxia-stimulated ATM activation regulates autophagy-associated exosome release from cancer-associated fibroblasts to promote cancer cell invasion.
    Xi L; Peng M; Liu S; Liu Y; Wan X; Hou Y; Qin Y; Yang L; Chen S; Zeng H; Teng Y; Cui X; Liu M
    J Extracell Vesicles; 2021 Sep; 10(11):e12146. PubMed ID: 34545708
    [TBL] [Abstract][Full Text] [Related]  

  • 6. ATM-Mediated Phosphorylation of Cortactin Involved in Actin Polymerization Promotes Breast Cancer Cells Migration and Invasion.
    Lang L; Hou Y; Chen Y; Tu G; Tao J; Yang D; Xi L; Fu L; Sun K; Yin J; Chen R; Peng M; Liu S; Liu M
    Cell Physiol Biochem; 2018; 51(6):2972-2988. PubMed ID: 30562756
    [TBL] [Abstract][Full Text] [Related]  

  • 7. The role of oxidized ATM in the regulation of oxidative stress-induced energy metabolism reprogramming of CAFs.
    Tang S; Yang L; Tang X; Liu M
    Cancer Lett; 2014 Oct; 353(2):133-44. PubMed ID: 25069040
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Epigenetic Reprogramming of Cancer-Associated Fibroblasts Deregulates Glucose Metabolism and Facilitates Progression of Breast Cancer.
    Becker LM; O'Connell JT; Vo AP; Cain MP; Tampe D; Bizarro L; Sugimoto H; McGow AK; Asara JM; Lovisa S; McAndrews KM; Zielinski R; Lorenzi PL; Zeisberg M; Raza S; LeBleu VS; Kalluri R
    Cell Rep; 2020 Jun; 31(9):107701. PubMed ID: 32492417
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Cancer-Associated Fibroblasts Accelerate Malignant Progression of Non-Small Cell Lung Cancer via Connexin 43-Formed Unidirectional Gap Junctional Intercellular Communication.
    Luo M; Luo Y; Mao N; Huang G; Teng C; Wang H; Wu J; Liao X; Yang J
    Cell Physiol Biochem; 2018; 51(1):315-336. PubMed ID: 30453281
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Dihydroartemisinin Inhibits the Proliferation of Leukemia Cells K562 by Suppressing PKM2 and GLUT1 Mediated Aerobic Glycolysis.
    Gao P; Shen S; Li X; Liu D; Meng Y; Liu Y; Zhu Y; Zhang J; Luo P; Gu L
    Drug Des Devel Ther; 2020; 14():2091-2100. PubMed ID: 32546972
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Cancer-associated fibroblasts enhance pancreatic cancer cell invasion by remodeling the metabolic conversion mechanism.
    Shan T; Chen S; Chen X; Lin WR; Li W; Ma J; Wu T; Cui X; Ji H; Li Y; Kang Y
    Oncol Rep; 2017 Apr; 37(4):1971-1979. PubMed ID: 28260082
    [TBL] [Abstract][Full Text] [Related]  

  • 12. ATM inhibitor KU-55933 induces apoptosis and inhibits motility by blocking GLUT1-mediated glucose uptake in aggressive cancer cells with sustained activation of Akt.
    Harris BRE; Zhang Y; Tao J; Shen R; Zhao X; Cleary MP; Wang T; Yang DQ
    FASEB J; 2021 Apr; 35(4):e21264. PubMed ID: 33715230
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Tumor microenvironment and metabolic synergy in breast cancers: critical importance of mitochondrial fuels and function.
    Martinez-Outschoorn U; Sotgia F; Lisanti MP
    Semin Oncol; 2014 Apr; 41(2):195-216. PubMed ID: 24787293
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Oxidized ATM protein kinase is a new signal transduction player that regulates glycolysis in CAFs as well as tumor growth and metastasis.
    Marín-Hernández Á; Rodríguez-Enríquez S; Moreno-Sánchez R
    EBioMedicine; 2019 Mar; 41():24-25. PubMed ID: 30846394
    [No Abstract]   [Full Text] [Related]  

  • 15. Metabolic reprogramming of cancer-associated fibroblasts by TGF-β drives tumor growth: connecting TGF-β signaling with "Warburg-like" cancer metabolism and L-lactate production.
    Guido C; Whitaker-Menezes D; Capparelli C; Balliet R; Lin Z; Pestell RG; Howell A; Aquila S; Andò S; Martinez-Outschoorn U; Sotgia F; Lisanti MP
    Cell Cycle; 2012 Aug; 11(16):3019-35. PubMed ID: 22874531
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Effects of shRNA-Mediated Silencing of PKM2 Gene on Aerobic Glycolysis, Cell Migration, Cell Invasion, and Apoptosis in Colorectal Cancer Cells.
    Yan XL; Zhang XB; Ao R; Guan L
    J Cell Biochem; 2017 Dec; 118(12):4792-4803. PubMed ID: 28543190
    [TBL] [Abstract][Full Text] [Related]  

  • 17. GRP78 is implicated in the modulation of tumor aerobic glycolysis by promoting autophagic degradation of IKKβ.
    Li Z; Wang Y; Newton IP; Zhang L; Ji P; Li Z
    Cell Signal; 2015 Jun; 27(6):1237-45. PubMed ID: 25748049
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Shikonin reverses cancer-associated fibroblast-induced gemcitabine resistance in pancreatic cancer cells by suppressing monocarboxylate transporter 4-mediated reverse Warburg effect.
    Hu X; Peng X; Zhang Y; Fan S; Liu X; Song Y; Ren S; Chen L; Chen Y; Wang R; Peng J; Shen X; Chen Y
    Phytomedicine; 2024 Jan; 123():155214. PubMed ID: 38134861
    [TBL] [Abstract][Full Text] [Related]  

  • 19. ITGB2-mediated metabolic switch in CAFs promotes OSCC proliferation by oxidation of NADH in mitochondrial oxidative phosphorylation system.
    Zhang X; Dong Y; Zhao M; Ding L; Yang X; Jing Y; Song Y; Chen S; Hu Q; Ni Y
    Theranostics; 2020; 10(26):12044-12059. PubMed ID: 33204328
    [No Abstract]   [Full Text] [Related]  

  • 20. Lactate secreted by PKM2 upregulation promotes Galectin-9-mediated immunosuppression via inhibiting NF-κB pathway in HNSCC.
    Chang H; Xu Q; Li J; Li M; Zhang Z; Ma H; Yang X
    Cell Death Dis; 2021 Jul; 12(8):725. PubMed ID: 34290225
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 39.