BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

271 related articles for article (PubMed ID: 30806671)

  • 1. Quantitative proteomics identifies proteins that resist translational repression and become dysregulated in ALS-FUS.
    Baron DM; Matheny T; Lin YC; Leszyk JD; Kenna K; Gall KV; Santos DP; Tischbein M; Funes S; Hayward LJ; Kiskinis E; Landers JE; Parker R; Shaffer SA; Bosco DA
    Hum Mol Genet; 2019 Jul; 28(13):2143-2160. PubMed ID: 30806671
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Ataxin-2 interacts with FUS and intermediate-length polyglutamine expansions enhance FUS-related pathology in amyotrophic lateral sclerosis.
    Farg MA; Soo KY; Warraich ST; Sundaramoorthy V; Blair IP; Atkin JD
    Hum Mol Genet; 2013 Feb; 22(4):717-28. PubMed ID: 23172909
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Rab1-dependent ER-Golgi transport dysfunction is a common pathogenic mechanism in SOD1, TDP-43 and FUS-associated ALS.
    Soo KY; Halloran M; Sundaramoorthy V; Parakh S; Toth RP; Southam KA; McLean CA; Lock P; King A; Farg MA; Atkin JD
    Acta Neuropathol; 2015 Nov; 130(5):679-97. PubMed ID: 26298469
    [TBL] [Abstract][Full Text] [Related]  

  • 4. ALS mutations of FUS suppress protein translation and disrupt the regulation of nonsense-mediated decay.
    Kamelgarn M; Chen J; Kuang L; Jin H; Kasarskis EJ; Zhu H
    Proc Natl Acad Sci U S A; 2018 Dec; 115(51):E11904-E11913. PubMed ID: 30455313
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Pur-alpha regulates cytoplasmic stress granule dynamics and ameliorates FUS toxicity.
    Daigle JG; Krishnamurthy K; Ramesh N; Casci I; Monaghan J; McAvoy K; Godfrey EW; Daniel DC; Johnson EM; Monahan Z; Shewmaker F; Pasinelli P; Pandey UB
    Acta Neuropathol; 2016 Apr; 131(4):605-20. PubMed ID: 26728149
    [TBL] [Abstract][Full Text] [Related]  

  • 6. ALS mutant FUS disrupts nuclear localization and sequesters wild-type FUS within cytoplasmic stress granules.
    Vance C; Scotter EL; Nishimura AL; Troakes C; Mitchell JC; Kathe C; Urwin H; Manser C; Miller CC; Hortobágyi T; Dragunow M; Rogelj B; Shaw CE
    Hum Mol Genet; 2013 Jul; 22(13):2676-88. PubMed ID: 23474818
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Directly converted patient-specific induced neurons mirror the neuropathology of FUS with disrupted nuclear localization in amyotrophic lateral sclerosis.
    Lim SM; Choi WJ; Oh KW; Xue Y; Choi JY; Kim SH; Nahm M; Kim YE; Lee J; Noh MY; Lee S; Hwang S; Ki CS; Fu XD; Kim SH
    Mol Neurodegener; 2016 Jan; 11():8. PubMed ID: 26795035
    [TBL] [Abstract][Full Text] [Related]  

  • 8. ALS mutant FUS proteins are recruited into stress granules in induced pluripotent stem cell-derived motoneurons.
    Lenzi J; De Santis R; de Turris V; Morlando M; Laneve P; Calvo A; Caliendo V; Chiò A; Rosa A; Bozzoni I
    Dis Model Mech; 2015 Jul; 8(7):755-66. PubMed ID: 26035390
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Amyotrophic lateral sclerosis-linked FUS/TLS alters stress granule assembly and dynamics.
    Baron DM; Kaushansky LJ; Ward CL; Sama RR; Chian RJ; Boggio KJ; Quaresma AJ; Nickerson JA; Bosco DA
    Mol Neurodegener; 2013 Aug; 8():30. PubMed ID: 24090136
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Arginine methylation by PRMT1 regulates nuclear-cytoplasmic localization and toxicity of FUS/TLS harbouring ALS-linked mutations.
    Tradewell ML; Yu Z; Tibshirani M; Boulanger MC; Durham HD; Richard S
    Hum Mol Genet; 2012 Jan; 21(1):136-49. PubMed ID: 21965298
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Comparative interactomics analysis of different ALS-associated proteins identifies converging molecular pathways.
    Blokhuis AM; Koppers M; Groen EJN; van den Heuvel DMA; Dini Modigliani S; Anink JJ; Fumoto K; van Diggelen F; Snelting A; Sodaar P; Verheijen BM; Demmers JAA; Veldink JH; Aronica E; Bozzoni I; den Hertog J; van den Berg LH; Pasterkamp RJ
    Acta Neuropathol; 2016 Aug; 132(2):175-196. PubMed ID: 27164932
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Autophagy meets fused in sarcoma-positive stress granules.
    Matus S; Bosco DA; Hetz C
    Neurobiol Aging; 2014 Dec; 35(12):2832-2835. PubMed ID: 25444610
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Proteomics analysis of FUS mutant human motoneurons reveals altered regulation of cytoskeleton and other ALS-linked proteins via 3'UTR binding.
    Garone MG; Alfano V; Salvatori B; Braccia C; Peruzzi G; Colantoni A; Bozzoni I; Armirotti A; Rosa A
    Sci Rep; 2020 Jul; 10(1):11827. PubMed ID: 32678235
    [TBL] [Abstract][Full Text] [Related]  

  • 14. HDAC6 inhibition reverses axonal transport defects in motor neurons derived from FUS-ALS patients.
    Guo W; Naujock M; Fumagalli L; Vandoorne T; Baatsen P; Boon R; Ordovás L; Patel A; Welters M; Vanwelden T; Geens N; Tricot T; Benoy V; Steyaert J; Lefebvre-Omar C; Boesmans W; Jarpe M; Sterneckert J; Wegner F; Petri S; Bohl D; Vanden Berghe P; Robberecht W; Van Damme P; Verfaillie C; Van Den Bosch L
    Nat Commun; 2017 Oct; 8(1):861. PubMed ID: 29021520
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Autophagy regulates amyotrophic lateral sclerosis-linked fused in sarcoma-positive stress granules in neurons.
    Ryu HH; Jun MH; Min KJ; Jang DJ; Lee YS; Kim HK; Lee JA
    Neurobiol Aging; 2014 Dec; 35(12):2822-2831. PubMed ID: 25216585
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Astrocytes expressing ALS-linked mutant FUS induce motor neuron death through release of tumor necrosis factor-alpha.
    Kia A; McAvoy K; Krishnamurthy K; Trotti D; Pasinelli P
    Glia; 2018 May; 66(5):1016-1033. PubMed ID: 29380416
    [TBL] [Abstract][Full Text] [Related]  

  • 17. ALS-linked FUS exerts a gain of toxic function involving aberrant p38 MAPK activation.
    Sama RR; Fallini C; Gatto R; McKeon JE; Song Y; Rotunno MS; Penaranda S; Abdurakhmanov I; Landers JE; Morfini G; Brady ST; Bosco DA
    Sci Rep; 2017 Mar; 7(1):115. PubMed ID: 28273913
    [TBL] [Abstract][Full Text] [Related]  

  • 18. In vivo stress granule misprocessing evidenced in a FUS knock-in ALS mouse model.
    Zhang X; Wang F; Hu Y; Chen R; Meng D; Guo L; Lv H; Guan J; Jia Y
    Brain; 2020 May; 143(5):1350-1367. PubMed ID: 32358598
    [TBL] [Abstract][Full Text] [Related]  

  • 19. FUS ALS neurons activate major stress pathways and reduce translation as an early protective mechanism against neurodegeneration.
    Szewczyk B; Günther R; Japtok J; Frech MJ; Naumann M; Lee HO; Hermann A
    Cell Rep; 2023 Feb; 42(2):112025. PubMed ID: 36696267
    [TBL] [Abstract][Full Text] [Related]  

  • 20. A complex of C9ORF72 and p62 uses arginine methylation to eliminate stress granules by autophagy.
    Chitiprolu M; Jagow C; Tremblay V; Bondy-Chorney E; Paris G; Savard A; Palidwor G; Barry FA; Zinman L; Keith J; Rogaeva E; Robertson J; Lavallée-Adam M; Woulfe J; Couture JF; Côté J; Gibbings D
    Nat Commun; 2018 Jul; 9(1):2794. PubMed ID: 30022074
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 14.