These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

228 related articles for article (PubMed ID: 30808748)

  • 21. Structure and Dynamics of the Huntingtin Exon-1 N-Terminus: A Solution NMR Perspective.
    Baias M; Smith PE; Shen K; Joachimiak LA; Żerko S; Koźmiński W; Frydman J; Frydman L
    J Am Chem Soc; 2017 Jan; 139(3):1168-1176. PubMed ID: 28085263
    [TBL] [Abstract][Full Text] [Related]  

  • 22. The 17-residue-long N terminus in huntingtin controls stepwise aggregation in solution and on membranes via different mechanisms.
    Pandey NK; Isas JM; Rawat A; Lee RV; Langen J; Pandey P; Langen R
    J Biol Chem; 2018 Feb; 293(7):2597-2605. PubMed ID: 29282287
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Folding Landscape of Mutant Huntingtin Exon1: Diffusible Multimers, Oligomers and Fibrils, and No Detectable Monomer.
    Sahoo B; Arduini I; Drombosky KW; Kodali R; Sanders LH; Greenamyre JT; Wetzel R
    PLoS One; 2016; 11(6):e0155747. PubMed ID: 27271685
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Dynamics of the Proline-Rich C-Terminus of Huntingtin Exon-1 Fibrils.
    Caulkins BG; Cervantes SA; Isas JM; Siemer AB
    J Phys Chem B; 2018 Oct; 122(41):9507-9515. PubMed ID: 30252478
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Probing the Interaction of Huntingtin Exon-1 Polypeptides with the Chaperonin Nanomachine GroEL.
    Wälti MA; Kotler SA; Clore GM
    Chembiochem; 2021 Jun; 22(11):1985-1991. PubMed ID: 33644966
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Inhibiting the nucleation of amyloid structure in a huntingtin fragment by targeting α-helix-rich oligomeric intermediates.
    Mishra R; Jayaraman M; Roland BP; Landrum E; Fullam T; Kodali R; Thakur AK; Arduini I; Wetzel R
    J Mol Biol; 2012 Feb; 415(5):900-17. PubMed ID: 22178478
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Divalent cations promote huntingtin fibril formation on endoplasmic reticulum derived and model membranes.
    Skeens A; Markle JM; Petipas G; Frey SL; Legleiter J
    Biochim Biophys Acta Biomembr; 2024 Aug; 1866(6):184339. PubMed ID: 38763270
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Molecular basis of Q-length selectivity for the MW1 antibody-huntingtin interaction.
    Bravo-Arredondo JM; Venkataraman R; Varkey J; Isas JM; Situ AJ; Xu H; Chen J; Ulmer TS; Langen R
    J Biol Chem; 2023 Apr; 299(4):104616. PubMed ID: 36931390
    [TBL] [Abstract][Full Text] [Related]  

  • 29. The folding equilibrium of huntingtin exon 1 monomer depends on its polyglutamine tract.
    Bravo-Arredondo JM; Kegulian NC; Schmidt T; Pandey NK; Situ AJ; Ulmer TS; Langen R
    J Biol Chem; 2018 Dec; 293(51):19613-19623. PubMed ID: 30315108
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Huntingtin exon 1 fibrils feature an interdigitated β-hairpin-based polyglutamine core.
    Hoop CL; Lin HK; Kar K; Magyarfalvi G; Lamley JM; Boatz JC; Mandal A; Lewandowski JR; Wetzel R; van der Wel PC
    Proc Natl Acad Sci U S A; 2016 Feb; 113(6):1546-51. PubMed ID: 26831073
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Effects of Macromolecular Cosolutes on the Kinetics of Huntingtin Aggregation Monitored by NMR Spectroscopy.
    Torricella F; Tugarinov V; Clore GM
    J Phys Chem Lett; 2024 Jun; 15(24):6375-6382. PubMed ID: 38857530
    [TBL] [Abstract][Full Text] [Related]  

  • 32. A comprehensive in silico analysis of huntingtin and its interactome.
    Brandi V; Di Lella V; Marino M; Ascenzi P; Polticelli F
    J Biomol Struct Dyn; 2018 Sep; 36(12):3155-3171. PubMed ID: 28920551
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Structural Basis of Huntingtin Fibril Polymorphism Revealed by Cryogenic Electron Microscopy of Exon 1 HTT Fibrils.
    Nazarov S; Chiki A; Boudeffa D; Lashuel HA
    J Am Chem Soc; 2022 Jun; 144(24):10723-10735. PubMed ID: 35679155
    [TBL] [Abstract][Full Text] [Related]  

  • 34. TiO
    Ceccon A; Tugarinov V; Clore GM
    J Am Chem Soc; 2019 Jan; 141(1):94-97. PubMed ID: 30540190
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Protofilament Structure and Supramolecular Polymorphism of Aggregated Mutant Huntingtin Exon 1.
    Boatz JC; Piretra T; Lasorsa A; Matlahov I; Conway JF; van der Wel PCA
    J Mol Biol; 2020 Jul; 432(16):4722-4744. PubMed ID: 32598938
    [TBL] [Abstract][Full Text] [Related]  

  • 36. A Liquid to Solid Phase Transition Underlying Pathological Huntingtin Exon1 Aggregation.
    Peskett TR; Rau F; O'Driscoll J; Patani R; Lowe AR; Saibil HR
    Mol Cell; 2018 May; 70(4):588-601.e6. PubMed ID: 29754822
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Structure of a single-chain Fv bound to the 17 N-terminal residues of huntingtin provides insights into pathogenic amyloid formation and suppression.
    De Genst E; Chirgadze DY; Klein FA; Butler DC; Matak-Vinković D; Trottier Y; Huston JS; Messer A; Dobson CM
    J Mol Biol; 2015 Jun; 427(12):2166-78. PubMed ID: 25861763
    [TBL] [Abstract][Full Text] [Related]  

  • 38. HSP90 recognizes the N-terminus of huntingtin involved in regulation of huntingtin aggregation by USP19.
    He WT; Xue W; Gao YG; Hong JY; Yue HW; Jiang LL; Hu HY
    Sci Rep; 2017 Nov; 7(1):14797. PubMed ID: 29093475
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Structural Model of the Proline-Rich Domain of Huntingtin Exon-1 Fibrils.
    Falk AS; Bravo-Arredondo JM; Varkey J; Pacheco S; Langen R; Siemer AB
    Biophys J; 2020 Nov; 119(10):2019-2028. PubMed ID: 33096080
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Investigating Mutations to Reduce Huntingtin Aggregation by Increasing Htt-N-Terminal Stability and Weakening Interactions with PolyQ Domain.
    Smaoui MR; Mazza-Anthony C; Waldispühl J
    Comput Math Methods Med; 2016; 2016():6247867. PubMed ID: 28096892
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 12.