401 related articles for article (PubMed ID: 30811988)
21. Cyclic GMP-AMP synthase is a cytosolic DNA sensor that activates the type I interferon pathway.
Sun L; Wu J; Du F; Chen X; Chen ZJ
Science; 2013 Feb; 339(6121):786-91. PubMed ID: 23258413
[TBL] [Abstract][Full Text] [Related]
22. Structural basis for sequestration and autoinhibition of cGAS by chromatin.
Michalski S; de Oliveira Mann CC; Stafford CA; Witte G; Bartho J; Lammens K; Hornung V; Hopfner KP
Nature; 2020 Nov; 587(7835):678-682. PubMed ID: 32911480
[TBL] [Abstract][Full Text] [Related]
23. Cyclic GMP-AMP Synthase Is an Innate Immune DNA Sensor for Mycobacterium tuberculosis.
Collins AC; Cai H; Li T; Franco LH; Li XD; Nair VR; Scharn CR; Stamm CE; Levine B; Chen ZJ; Shiloh MU
Cell Host Microbe; 2015 Jun; 17(6):820-8. PubMed ID: 26048137
[TBL] [Abstract][Full Text] [Related]
24. Pivotal roles of cGAS-cGAMP signaling in antiviral defense and immune adjuvant effects.
Li XD; Wu J; Gao D; Wang H; Sun L; Chen ZJ
Science; 2013 Sep; 341(6152):1390-4. PubMed ID: 23989956
[TBL] [Abstract][Full Text] [Related]
25. Nuclear cGAS suppresses DNA repair and promotes tumorigenesis.
Liu H; Zhang H; Wu X; Ma D; Wu J; Wang L; Jiang Y; Fei Y; Zhu C; Tan R; Jungblut P; Pei G; Dorhoi A; Yan Q; Zhang F; Zheng R; Liu S; Liang H; Liu Z; Yang H; Chen J; Wang P; Tang T; Peng W; Hu Z; Xu Z; Huang X; Wang J; Li H; Zhou Y; Liu F; Yan D; Kaufmann SHE; Chen C; Mao Z; Ge B
Nature; 2018 Nov; 563(7729):131-136. PubMed ID: 30356214
[TBL] [Abstract][Full Text] [Related]
26. IFI16 and cGAS cooperate in the activation of STING during DNA sensing in human keratinocytes.
Almine JF; O'Hare CA; Dunphy G; Haga IR; Naik RJ; Atrih A; Connolly DJ; Taylor J; Kelsall IR; Bowie AG; Beard PM; Unterholzner L
Nat Commun; 2017 Feb; 8():14392. PubMed ID: 28194029
[TBL] [Abstract][Full Text] [Related]
27. Manganese Increases the Sensitivity of the cGAS-STING Pathway for Double-Stranded DNA and Is Required for the Host Defense against DNA Viruses.
Wang C; Guan Y; Lv M; Zhang R; Guo Z; Wei X; Du X; Yang J; Li T; Wan Y; Su X; Huang X; Jiang Z
Immunity; 2018 Apr; 48(4):675-687.e7. PubMed ID: 29653696
[TBL] [Abstract][Full Text] [Related]
28. The innate immune DNA sensor cGAS: A membrane, cytosolic, or nuclear protein?
Gekara NO; Jiang H
Sci Signal; 2019 May; 12(581):. PubMed ID: 31088977
[TBL] [Abstract][Full Text] [Related]
29. Viral DNA Sensors IFI16 and Cyclic GMP-AMP Synthase Possess Distinct Functions in Regulating Viral Gene Expression, Immune Defenses, and Apoptotic Responses during Herpesvirus Infection.
Diner BA; Lum KK; Toettcher JE; Cristea IM
mBio; 2016 Nov; 7(6):. PubMed ID: 27935834
[TBL] [Abstract][Full Text] [Related]
30. Leaked Mitochondrial C1QBP Inhibits Activation of the DNA Sensor cGAS.
Song K; Wu Y; Fu B; Wang L; Hao W; Hua F; Sun Y; Dorf ME; Li S
J Immunol; 2021 Oct; 207(8):2155-2166. PubMed ID: 34526378
[TBL] [Abstract][Full Text] [Related]
31. SENP7 Potentiates cGAS Activation by Relieving SUMO-Mediated Inhibition of Cytosolic DNA Sensing.
Cui Y; Yu H; Zheng X; Peng R; Wang Q; Zhou Y; Wang R; Wang J; Qu B; Shen N; Guo Q; Liu X; Wang C
PLoS Pathog; 2017 Jan; 13(1):e1006156. PubMed ID: 28095500
[TBL] [Abstract][Full Text] [Related]
32. Regulation and function of the cGAS-STING pathway of cytosolic DNA sensing.
Chen Q; Sun L; Chen ZJ
Nat Immunol; 2016 Sep; 17(10):1142-9. PubMed ID: 27648547
[TBL] [Abstract][Full Text] [Related]
33. Cyclic GMP-AMP as an Endogenous Second Messenger in Innate Immune Signaling by Cytosolic DNA.
Kato K; Omura H; Ishitani R; Nureki O
Annu Rev Biochem; 2017 Jun; 86():541-566. PubMed ID: 28399655
[TBL] [Abstract][Full Text] [Related]
34. Phosphoinositide Interactions Position cGAS at the Plasma Membrane to Ensure Efficient Distinction between Self- and Viral DNA.
Barnett KC; Coronas-Serna JM; Zhou W; Ernandes MJ; Cao A; Kranzusch PJ; Kagan JC
Cell; 2019 Mar; 176(6):1432-1446.e11. PubMed ID: 30827685
[TBL] [Abstract][Full Text] [Related]
35. MARCH8 attenuates cGAS-mediated innate immune responses through ubiquitylation.
Yang X; Shi C; Li H; Shen S; Su C; Yin H
Sci Signal; 2022 May; 15(732):eabk3067. PubMed ID: 35503863
[TBL] [Abstract][Full Text] [Related]
36. Molecular evolutionary and structural analysis of the cytosolic DNA sensor cGAS and STING.
Wu X; Wu FH; Wang X; Wang L; Siedow JN; Zhang W; Pei ZM
Nucleic Acids Res; 2014 Jul; 42(13):8243-57. PubMed ID: 24981511
[TBL] [Abstract][Full Text] [Related]
37. The Cytoplasmic DNA Sensor cGAS Promotes Mitotic Cell Death.
Zierhut C; Yamaguchi N; Paredes M; Luo JD; Carroll T; Funabiki H
Cell; 2019 Jul; 178(2):302-315.e23. PubMed ID: 31299200
[TBL] [Abstract][Full Text] [Related]
38. The cytosolic DNA sensor cGAS forms an oligomeric complex with DNA and undergoes switch-like conformational changes in the activation loop.
Zhang X; Wu J; Du F; Xu H; Sun L; Chen Z; Brautigam CA; Zhang X; Chen ZJ
Cell Rep; 2014 Feb; 6(3):421-30. PubMed ID: 24462292
[TBL] [Abstract][Full Text] [Related]
39. Sensing Cytosolic DNA Lowers Blood Pressure by Direct cGAMP-Dependent PKGI Activation.
Su J; Coleman P; Ntorla A; Anderson R; Shattock MJ; Burgoyne JR
Circulation; 2023 Sep; 148(13):1023-1034. PubMed ID: 37548012
[TBL] [Abstract][Full Text] [Related]
40. How Does cGAS Avoid Sensing Self-DNA under Normal Physiological Conditions?
Zheng W; Chen N; Meurens F; Zheng W; Zhu J
Int J Mol Sci; 2023 Sep; 24(19):. PubMed ID: 37834184
[TBL] [Abstract][Full Text] [Related]
[Previous] [Next] [New Search]
