BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

241 related articles for article (PubMed ID: 30814129)

  • 1. HDAC1 Is a Required Cofactor of CBFβ-SMMHC and a Potential Therapeutic Target in Inversion 16 Acute Myeloid Leukemia.
    Richter LE; Wang Y; Becker ME; Coburn RA; Williams JT; Amador C; Hyde RK
    Mol Cancer Res; 2019 Jun; 17(6):1241-1252. PubMed ID: 30814129
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Runx1 is required for hematopoietic defects and leukemogenesis in Cbfb-MYH11 knock-in mice.
    Hyde RK; Zhao L; Alemu L; Liu PP
    Leukemia; 2015 Aug; 29(8):1771-8. PubMed ID: 25742748
    [TBL] [Abstract][Full Text] [Related]  

  • 3. RUNX1 and CBFβ-SMMHC transactivate target genes together in abnormal myeloid progenitors for leukemia development.
    Zhen T; Cao Y; Ren G; Zhao L; Hyde RK; Lopez G; Feng D; Alemu L; Zhao K; Liu PP
    Blood; 2020 Nov; 136(21):2373-2385. PubMed ID: 32929473
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Molecular Basis and Targeted Inhibition of CBFβ-SMMHC Acute Myeloid Leukemia.
    Castilla LH; Bushweller JH
    Adv Exp Med Biol; 2017; 962():229-244. PubMed ID: 28299661
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Targeting binding partners of the CBFβ-SMMHC fusion protein for the treatment of inversion 16 acute myeloid leukemia.
    Richter L; Wang Y; Hyde RK
    Oncotarget; 2016 Oct; 7(40):66255-66266. PubMed ID: 27542261
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Core-binding factor beta (CBFbeta), but not CBFbeta-smooth muscle myosin heavy chain, rescues definitive hematopoiesis in CBFbeta-deficient embryonic stem cells.
    Miller JD; Stacy T; Liu PP; Speck NA
    Blood; 2001 Apr; 97(8):2248-56. PubMed ID: 11290585
    [TBL] [Abstract][Full Text] [Related]  

  • 7. FLT3-ITD cooperates with inv(16) to promote progression to acute myeloid leukemia.
    Kim HG; Kojima K; Swindle CS; Cotta CV; Huo Y; Reddy V; Klug CA
    Blood; 2008 Feb; 111(3):1567-74. PubMed ID: 17967943
    [TBL] [Abstract][Full Text] [Related]  

  • 8. CBFβ-SMMHC Inhibition Triggers Apoptosis by Disrupting MYC Chromatin Dynamics in Acute Myeloid Leukemia.
    Pulikkan JA; Hegde M; Ahmad HM; Belaghzal H; Illendula A; Yu J; O'Hagan K; Ou J; Muller-Tidow C; Wolfe SA; Zhu LJ; Dekker J; Bushweller JH; Castilla LH
    Cell; 2018 Jun; 174(1):172-186.e21. PubMed ID: 29958106
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Cbfbeta reduces Cbfbeta-SMMHC-associated acute myeloid leukemia in mice.
    Heilman SA; Kuo YH; Goudswaard CS; Valk PJ; Castilla LH
    Cancer Res; 2006 Dec; 66(23):11214-8. PubMed ID: 17145866
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Methylation-independent silencing of the tumor suppressor INK4b (p15) by CBFbeta-SMMHC in acute myelogenous leukemia with inv(16).
    Markus J; Garin MT; Bies J; Galili N; Raza A; Thirman MJ; Le Beau MM; Rowley JD; Liu PP; Wolff L
    Cancer Res; 2007 Feb; 67(3):992-1000. PubMed ID: 17283131
    [TBL] [Abstract][Full Text] [Related]  

  • 11. The inv(16) fusion protein associates with corepressors via a smooth muscle myosin heavy-chain domain.
    Durst KL; Lutterbach B; Kummalue T; Friedman AD; Hiebert SW
    Mol Cell Biol; 2003 Jan; 23(2):607-19. PubMed ID: 12509458
    [TBL] [Abstract][Full Text] [Related]  

  • 12. CBFB-MYH11/RUNX1 together with a compendium of hematopoietic regulators, chromatin modifiers and basal transcription factors occupies self-renewal genes in inv(16) acute myeloid leukemia.
    Mandoli A; Singh AA; Jansen PW; Wierenga AT; Riahi H; Franci G; Prange K; Saeed S; Vellenga E; Vermeulen M; Stunnenberg HG; Martens JH
    Leukemia; 2014 Apr; 28(4):770-8. PubMed ID: 24002588
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Chemical biology. A small-molecule inhibitor of the aberrant transcription factor CBFβ-SMMHC delays leukemia in mice.
    Illendula A; Pulikkan JA; Zong H; Grembecka J; Xue L; Sen S; Zhou Y; Boulton A; Kuntimaddi A; Gao Y; Rajewski RA; Guzman ML; Castilla LH; Bushweller JH
    Science; 2015 Feb; 347(6223):779-84. PubMed ID: 25678665
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Immunohistochemical analysis of CBFbeta-SMMHC protein reveals a unique nuclear localization in acute myeloid leukemia with inv(16)(p13q22).
    Zhao W; Claxton DF; Medeiros LJ; Lu D; Vadhan-Raj S; Kantarjian HM; Nguyen MH; Bueso-Ramos CE
    Am J Surg Pathol; 2006 Nov; 30(11):1436-44. PubMed ID: 17063086
    [TBL] [Abstract][Full Text] [Related]  

  • 15. The leukemic protein core binding factor beta (CBFbeta)-smooth-muscle myosin heavy chain sequesters CBFalpha2 into cytoskeletal filaments and aggregates.
    Adya N; Stacy T; Speck NA; Liu PP
    Mol Cell Biol; 1998 Dec; 18(12):7432-43. PubMed ID: 9819429
    [TBL] [Abstract][Full Text] [Related]  

  • 16. NrasG12D oncoprotein inhibits apoptosis of preleukemic cells expressing Cbfβ-SMMHC via activation of MEK/ERK axis.
    Xue L; Pulikkan JA; Valk PJ; Castilla LH
    Blood; 2014 Jul; 124(3):426-36. PubMed ID: 24894773
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Characterization and use of an antibody detecting the CBFbeta-SMMHC fusion protein in inv(16)/t(16;16)-associated acute myeloid leukemias.
    Viswanatha DS; Chen I; Liu PP; Slovak ML; Rankin C; Head DR; Willman CL
    Blood; 1998 Mar; 91(6):1882-90. PubMed ID: 9490670
    [TBL] [Abstract][Full Text] [Related]  

  • 18.
    Zhen T; Kwon EM; Zhao L; Hsu J; Hyde RK; Lu Y; Alemu L; Speck NA; Liu PP
    Blood; 2017 Nov; 130(22):2431-2442. PubMed ID: 29018080
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Role of Cbfb in hematopoiesis and perturbations resulting from expression of the leukemogenic fusion gene Cbfb-MYH11.
    Kundu M; Chen A; Anderson S; Kirby M; Xu L; Castilla LH; Bodine D; Liu PP
    Blood; 2002 Oct; 100(7):2449-56. PubMed ID: 12239155
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Core binding factor beta-smooth muscle myosin heavy chain chimeric protein involved in acute myeloid leukemia forms unusual nuclear rod-like structures in transformed NIH 3T3 cells.
    Wijmenga C; Gregory PE; Hajra A; Schröck E; Ried T; Eils R; Liu PP; Collins FS
    Proc Natl Acad Sci U S A; 1996 Feb; 93(4):1630-5. PubMed ID: 8643682
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 13.