BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

106 related articles for article (PubMed ID: 30814273)

  • 1. Azadirachtin inhibits amyloid formation, disaggregates pre-formed fibrils and protects pancreatic β-cells from human islet amyloid polypeptide/amylin-induced cytotoxicity.
    Dubey R; Patil K; Dantu SC; Sardesai DM; Bhatia P; Malik N; Acharya JD; Sarkar S; Ghosh S; Chakrabarti R; Sharma S; Kumar A
    Biochem J; 2019 Mar; 476(5):889-907. PubMed ID: 30814273
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Islet amyloid polypeptide aggregation exerts cytotoxic and proinflammatory effects on the islet vasculature in mice.
    Castillo JJ; Aplin AC; Hackney DJ; Hogan MF; Esser N; Templin AT; Akter R; Kahn SE; Raleigh DP; Zraika S; Hull RL
    Diabetologia; 2022 Oct; 65(10):1687-1700. PubMed ID: 35871651
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Defining the molecular basis of amyloid inhibitors: human islet amyloid polypeptide-insulin interactions.
    Susa AC; Wu C; Bernstein SL; Dupuis NF; Wang H; Raleigh DP; Shea JE; Bowers MT
    J Am Chem Soc; 2014 Sep; 136(37):12912-9. PubMed ID: 25144879
    [TBL] [Abstract][Full Text] [Related]  

  • 4. cJUN N-terminal kinase (JNK) activation mediates islet amyloid-induced beta cell apoptosis in cultured human islet amyloid polypeptide transgenic mouse islets.
    Subramanian SL; Hull RL; Zraika S; Aston-Mourney K; Udayasankar J; Kahn SE
    Diabetologia; 2012 Jan; 55(1):166-74. PubMed ID: 22038516
    [TBL] [Abstract][Full Text] [Related]  

  • 5. RIPK3 promotes islet amyloid-induced β-cell loss and glucose intolerance in a humanized mouse model of type 2 diabetes.
    Mukherjee N; Contreras CJ; Lin L; Colglazier KA; Mather EG; Kalwat MA; Esser N; Kahn SE; Templin AT
    Mol Metab; 2024 Feb; 80():101877. PubMed ID: 38218538
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Bisphenol A accelerates toxic amyloid formation of human islet amyloid polypeptide: a possible link between bisphenol A exposure and type 2 diabetes.
    Gong H; Zhang X; Cheng B; Sun Y; Li C; Li T; Zheng L; Huang K
    PLoS One; 2013; 8(1):e54198. PubMed ID: 23372685
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Human islet amyloid polypeptide-induced β-cell cytotoxicity is linked to formation of α-sheet structure.
    Hsu CC; Templin AT; Prosswimmer T; Shea D; Li J; Brooks-Worrell B; Kahn SE; Daggett V
    Protein Sci; 2024 Feb; 33(2):e4854. PubMed ID: 38062941
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Probing ion channel activity of human islet amyloid polypeptide (amylin).
    Zhao J; Luo Y; Jang H; Yu X; Wei G; Nussinov R; Zheng J
    Biochim Biophys Acta; 2012 Dec; 1818(12):3121-30. PubMed ID: 22935354
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Graphene oxide inhibits hIAPP amyloid fibrillation and toxicity in insulin-producing NIT-1 cells.
    Nedumpully-Govindan P; Gurzov EN; Chen P; Pilkington EH; Stanley WJ; Litwak SA; Davis TP; Ke PC; Ding F
    Phys Chem Chem Phys; 2016 Jan; 18(1):94-100. PubMed ID: 26625841
    [TBL] [Abstract][Full Text] [Related]  

  • 10. How type II diabetes-related islet amyloid polypeptide damages lipid bilayers.
    Lee CC; Sun Y; Huang HW
    Biophys J; 2012 Mar; 102(5):1059-68. PubMed ID: 22404928
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Experimental and computational investigation of the effect of Hsc70 structural variants on inhibiting amylin aggregation.
    Chaari A; Saikia N; Paul P; Yousef M; Ding F; Ladjimi M
    Biophys Chem; 2024 Jun; 309():107235. PubMed ID: 38608617
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Tryptophan-galactosylamine conjugates inhibit and disaggregate amyloid fibrils of Aβ42 and hIAPP peptides while reducing their toxicity.
    Paul A; Frenkel-Pinter M; Escobar Alvarez D; Milordini G; Gazit E; Zacco E; Segal D
    Commun Biol; 2020 Sep; 3(1):484. PubMed ID: 32879439
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Natural compound plumbagin based inhibition of hIAPP revealed by Markov state models based on MD data along with experimental validations.
    Nabi F; Ahmad O; Khan A; Hassan MN; Hisamuddin M; Malik S; Chaari A; Khan RH
    Proteins; 2024 Mar; ():. PubMed ID: 38497314
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Exploring the Role of Anionic Lipid Nanodomains in the Membrane Disruption and Protein Folding of Human Islet Amyloid Polypeptide Oligomers on Lipid Membrane Surfaces Using Multiscale Molecular Dynamics Simulations.
    Nguyen N; Lewis A; Pham T; Sikazwe D; Cheng KH
    Molecules; 2023 May; 28(10):. PubMed ID: 37241931
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Analysis of Sheep and Goat IAPP Provides Insight into IAPP Amyloidogenicity and Cytotoxicity.
    Miller MET; Li MH; Baghai A; Peetz VH; Zhyvoloup A; Raleigh DP
    Biochemistry; 2022 Nov; 61(22):2531-2545. PubMed ID: 36286531
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Structural Insights into Seeding Mechanisms of hIAPP Fibril Formation.
    Suladze S; Sustay Martinez C; Rodriguez Camargo DC; Engler J; Rodina N; Sarkar R; Zacharias M; Reif B
    J Am Chem Soc; 2024 May; 146(20):13783-13796. PubMed ID: 38723619
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Effect of proline mutations on the monomer conformations of amylin.
    Chiu CC; Singh S; de Pablo JJ
    Biophys J; 2013 Sep; 105(5):1227-35. PubMed ID: 24010666
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Pancreatic β-Cell Membrane Fluidity and Toxicity Induced by Human Islet Amyloid Polypeptide Species.
    Pilkington EH; Gurzov EN; Kakinen A; Litwak SA; Stanley WJ; Davis TP; Ke PC
    Sci Rep; 2016 Feb; 6():21274. PubMed ID: 26880502
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Aromaticity and amyloid formation: effect of π-electron distribution and aryl substituent geometry on the self-assembly of peptides derived from hIAPP(22-29).
    Profit AA; Vedad J; Saleh M; Desamero RZ
    Arch Biochem Biophys; 2015 Feb; 567():46-58. PubMed ID: 25524740
    [TBL] [Abstract][Full Text] [Related]  

  • 20. γ-AApeptides-based Small Molecule Ligands That Disaggregate Human Islet Amyloid Polypeptide.
    Bolarinwa O; Li C; Khadka N; Li Q; Wang Y; Pan J; Cai J
    Sci Rep; 2020 Jan; 10(1):95. PubMed ID: 31919432
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 6.