BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

344 related articles for article (PubMed ID: 30819820)

  • 1. CDK12 phosphorylates 4E-BP1 to enable mTORC1-dependent translation and mitotic genome stability.
    Choi SH; Martinez TF; Kim S; Donaldson C; Shokhirev MN; Saghatelian A; Jones KA
    Genes Dev; 2019 Apr; 33(7-8):418-435. PubMed ID: 30819820
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Mitotic protein kinase CDK1 phosphorylation of mRNA translation regulator 4E-BP1 Ser83 may contribute to cell transformation.
    Velásquez C; Cheng E; Shuda M; Lee-Oesterreich PJ; Pogge von Strandmann L; Gritsenko MA; Jacobs JM; Moore PS; Chang Y
    Proc Natl Acad Sci U S A; 2016 Jul; 113(30):8466-71. PubMed ID: 27402756
    [TBL] [Abstract][Full Text] [Related]  

  • 3. CDK1 substitutes for mTOR kinase to activate mitotic cap-dependent protein translation.
    Shuda M; Velásquez C; Cheng E; Cordek DG; Kwun HJ; Chang Y; Moore PS
    Proc Natl Acad Sci U S A; 2015 May; 112(19):5875-82. PubMed ID: 25883264
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Mitosis-related phosphorylation of the eukaryotic translation suppressor 4E-BP1 and its interaction with eukaryotic translation initiation factor 4E (eIF4E).
    Sun R; Cheng E; Velásquez C; Chang Y; Moore PS
    J Biol Chem; 2019 Aug; 294(31):11840-11852. PubMed ID: 31201269
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Molecular mechanism of the dual activity of 4EGI-1: Dissociating eIF4G from eIF4E but stabilizing the binding of unphosphorylated 4E-BP1.
    Sekiyama N; Arthanari H; Papadopoulos E; Rodriguez-Mias RA; Wagner G; Léger-Abraham M
    Proc Natl Acad Sci U S A; 2015 Jul; 112(30):E4036-45. PubMed ID: 26170285
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Eukaryotic Initiation Factor 4E (eIF4E) sequestration mediates 4E-BP1 response to rapamycin.
    Batool A; Majeed ST; Aashaq S; Majeed R; Shah G; Nazir N; Andrabi KI
    Int J Biol Macromol; 2019 Mar; 125():651-659. PubMed ID: 30552925
    [TBL] [Abstract][Full Text] [Related]  

  • 7. The dynamic mechanism of 4E-BP1 recognition and phosphorylation by mTORC1.
    Böhm R; Imseng S; Jakob RP; Hall MN; Maier T; Hiller S
    Mol Cell; 2021 Jun; 81(11):2403-2416.e5. PubMed ID: 33852892
    [TBL] [Abstract][Full Text] [Related]  

  • 8. mTORC1 signalling and eIF4E/4E-BP1 translation initiation factor stoichiometry influence recombinant protein productivity from GS-CHOK1 cells.
    Jossé L; Xie J; Proud CG; Smales CM
    Biochem J; 2016 Dec; 473(24):4651-4664. PubMed ID: 27760840
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Vesicular stomatitis virus infection alters the eIF4F translation initiation complex and causes dephosphorylation of the eIF4E binding protein 4E-BP1.
    Connor JH; Lyles DS
    J Virol; 2002 Oct; 76(20):10177-87. PubMed ID: 12239292
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Regulated in development and DNA damage 1 is necessary for hyperglycemia-induced vascular endothelial growth factor expression in the retina of diabetic rodents.
    Dennis MD; Kimball SR; Fort PE; Jefferson LS
    J Biol Chem; 2015 Feb; 290(6):3865-74. PubMed ID: 25548280
    [TBL] [Abstract][Full Text] [Related]  

  • 11. AKT inhibition overcomes rapamycin resistance by enhancing the repressive function of PRAS40 on mTORC1/4E-BP1 axis.
    Mi W; Ye Q; Liu S; She QB
    Oncotarget; 2015 Jun; 6(16):13962-77. PubMed ID: 25961827
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Icariside II, a natural mTOR inhibitor, disrupts aberrant energy homeostasis via suppressing mTORC1-4E-BP1 axis in sarcoma cells.
    Zhang C; Yang L; Geng YD; An FL; Xia YZ; Guo C; Luo JG; Zhang LY; Guo QL; Kong LY
    Oncotarget; 2016 May; 7(19):27819-37. PubMed ID: 27056897
    [TBL] [Abstract][Full Text] [Related]  

  • 13. RPPA-based protein profiling reveals eIF4G overexpression and 4E-BP1 serine 65 phosphorylation as molecular events that correspond with a pro-survival phenotype in chronic lymphocytic leukemia.
    Shull AY; Noonepalle SK; Awan FT; Liu J; Pei L; Bollag RJ; Salman H; Ding Z; Shi H
    Oncotarget; 2015 Jun; 6(16):14632-45. PubMed ID: 25999352
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Association between LRRK2 and 4E-BP1 protein levels in normal and malignant cells.
    Pons B; Armengol G; Livingstone M; López L; Coch L; Sonenberg N; Ramón y Cajal S
    Oncol Rep; 2012 Jan; 27(1):225-31. PubMed ID: 21922152
    [TBL] [Abstract][Full Text] [Related]  

  • 15. 4E-BP1, a multifactor regulated multifunctional protein.
    Qin X; Jiang B; Zhang Y
    Cell Cycle; 2016; 15(6):781-6. PubMed ID: 26901143
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Mitotic CDK1 and 4E-BP1 II: A single phosphomimetic mutation in 4E-BP1 induces glucose intolerance in mice.
    Cao S; Jurczak MJ; Shuda Y; Sun R; Shuda M; Chang Y; Moore PS
    PLoS One; 2023; 18(3):e0282914. PubMed ID: 36897840
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Nuclear-targeted 4E-BP1 is dephosphorylated, induces nuclear translocation of eIF4E, and alters mRNA translation.
    Takahashi S; Shibutani S; Iwata H
    Exp Cell Res; 2022 Sep; 418(1):113246. PubMed ID: 35697076
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Role of p70S6K1-mediated phosphorylation of eIF4B and PDCD4 proteins in the regulation of protein synthesis.
    Dennis MD; Jefferson LS; Kimball SR
    J Biol Chem; 2012 Dec; 287(51):42890-9. PubMed ID: 23105104
    [TBL] [Abstract][Full Text] [Related]  

  • 19. La-related Protein 1 (LARP1) Represses Terminal Oligopyrimidine (TOP) mRNA Translation Downstream of mTOR Complex 1 (mTORC1).
    Fonseca BD; Zakaria C; Jia JJ; Graber TE; Svitkin Y; Tahmasebi S; Healy D; Hoang HD; Jensen JM; Diao IT; Lussier A; Dajadian C; Padmanabhan N; Wang W; Matta-Camacho E; Hearnden J; Smith EM; Tsukumo Y; Yanagiya A; Morita M; Petroulakis E; González JL; Hernández G; Alain T; Damgaard CK
    J Biol Chem; 2015 Jun; 290(26):15996-6020. PubMed ID: 25940091
    [TBL] [Abstract][Full Text] [Related]  

  • 20. A unifying model for mTORC1-mediated regulation of mRNA translation.
    Thoreen CC; Chantranupong L; Keys HR; Wang T; Gray NS; Sabatini DM
    Nature; 2012 May; 485(7396):109-13. PubMed ID: 22552098
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 18.