BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

448 related articles for article (PubMed ID: 30820351)

  • 1. Synergy from gene expression and network mining (SynGeNet) method predicts synergistic drug combinations for diverse melanoma genomic subtypes.
    Regan-Fendt KE; Xu J; DiVincenzo M; Duggan MC; Shakya R; Na R; Carson WE; Payne PRO; Li F
    NPJ Syst Biol Appl; 2019; 5():6. PubMed ID: 30820351
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Integrative network and transcriptomics-based approach predicts genotype- specific drug combinations for melanoma.
    Regan KE; Payne PRO; Li F
    AMIA Jt Summits Transl Sci Proc; 2017; 2017():247-256. PubMed ID: 28815138
    [TBL] [Abstract][Full Text] [Related]  

  • 3. In silico drug combination discovery for personalized cancer therapy.
    Jeon M; Kim S; Park S; Lee H; Kang J
    BMC Syst Biol; 2018 Mar; 12(Suppl 2):16. PubMed ID: 29560824
    [TBL] [Abstract][Full Text] [Related]  

  • 4. A Computational Approach for Identifying Synergistic Drug Combinations.
    Gayvert KM; Aly O; Platt J; Bosenberg MW; Stern DF; Elemento O
    PLoS Comput Biol; 2017 Jan; 13(1):e1005308. PubMed ID: 28085880
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Diffusion mapping of drug targets on disease signaling network elements reveals drug combination strategies.
    Xu J; Regan-Fendt K; Deng S; Carson WE; Payne PRO; Li F
    Pac Symp Biocomput; 2018; 23():92-103. PubMed ID: 29218872
    [TBL] [Abstract][Full Text] [Related]  

  • 6. An integrated framework for identification of effective and synergistic anti-cancer drug combinations.
    Sharma A; Rani R
    J Bioinform Comput Biol; 2018 Oct; 16(5):1850017. PubMed ID: 30304987
    [TBL] [Abstract][Full Text] [Related]  

  • 7. The discovery of vemurafenib for the treatment of BRAF-mutated metastatic melanoma.
    Kim A; Cohen MS
    Expert Opin Drug Discov; 2016 Sep; 11(9):907-16. PubMed ID: 27327499
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Selective Targeting of CTNBB1-, KRAS- or MYC-Driven Cell Growth by Combinations of Existing Drugs.
    Uitdehaag JC; de Roos JA; van Doornmalen AM; Prinsen MB; Spijkers-Hagelstein JA; de Vetter JR; de Man J; Buijsman RC; Zaman GJ
    PLoS One; 2015; 10(5):e0125021. PubMed ID: 26018524
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Kinase inhibitor library screening identifies synergistic drug combinations effective in sensitive and resistant melanoma cells.
    Margue C; Philippidou D; Kozar I; Cesi G; Felten P; Kulms D; Letellier E; Haan C; Kreis S
    J Exp Clin Cancer Res; 2019 Feb; 38(1):56. PubMed ID: 30728057
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Prediction of synergistic anti-cancer drug combinations based on drug target network and drug induced gene expression profiles.
    Li X; Xu Y; Cui H; Huang T; Wang D; Lian B; Li W; Qin G; Chen L; Xie L
    Artif Intell Med; 2017 Nov; 83():35-43. PubMed ID: 28583437
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Inhibition of oncogenic BRAF activity by indole-3-carbinol disrupts microphthalmia-associated transcription factor expression and arrests melanoma cell proliferation.
    Kundu A; Quirit JG; Khouri MG; Firestone GL
    Mol Carcinog; 2017 Jan; 56(1):49-61. PubMed ID: 26878440
    [TBL] [Abstract][Full Text] [Related]  

  • 12. BRAF
    Lunavat TR; Cheng L; Einarsdottir BO; Olofsson Bagge R; Veppil Muralidharan S; Sharples RA; Lässer C; Gho YS; Hill AF; Nilsson JA; Lötvall J
    Proc Natl Acad Sci U S A; 2017 Jul; 114(29):E5930-E5939. PubMed ID: 28684402
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Comparison of dabrafenib and trametinib combination therapy with vemurafenib monotherapy on health-related quality of life in patients with unresectable or metastatic cutaneous BRAF Val600-mutation-positive melanoma (COMBI-v): results of a phase 3, open-label, randomised trial.
    Grob JJ; Amonkar MM; Karaszewska B; Schachter J; Dummer R; Mackiewicz A; Stroyakovskiy D; Drucis K; Grange F; Chiarion-Sileni V; Rutkowski P; Lichinitser M; Levchenko E; Wolter P; Hauschild A; Long GV; Nathan P; Ribas A; Flaherty K; Sun P; Legos JJ; McDowell DO; Mookerjee B; Schadendorf D; Robert C
    Lancet Oncol; 2015 Oct; 16(13):1389-98. PubMed ID: 26433819
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Community assessment to advance computational prediction of cancer drug combinations in a pharmacogenomic screen.
    Menden MP; Wang D; Mason MJ; Szalai B; Bulusu KC; Guan Y; Yu T; Kang J; Jeon M; Wolfinger R; Nguyen T; Zaslavskiy M; ; Jang IS; Ghazoui Z; Ahsen ME; Vogel R; Neto EC; Norman T; Tang EKY; Garnett MJ; Veroli GYD; Fawell S; Stolovitzky G; Guinney J; Dry JR; Saez-Rodriguez J
    Nat Commun; 2019 Jun; 10(1):2674. PubMed ID: 31209238
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Metabolic targeting synergizes with MAPK inhibition and delays drug resistance in melanoma.
    Brummer C; Faerber S; Bruss C; Blank C; Lacroix R; Haferkamp S; Herr W; Kreutz M; Renner K
    Cancer Lett; 2019 Feb; 442():453-463. PubMed ID: 30481565
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Integrated Genomics Identifies miR-32/MCL-1 Pathway as a Critical Driver of Melanomagenesis: Implications for miR-Replacement and Combination Therapy.
    Mishra PJ; Mishra PJ; Merlino G
    PLoS One; 2016; 11(11):e0165102. PubMed ID: 27846237
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Feasibility of Ultra-High-Throughput Functional Screening of Melanoma Biopsies for Discovery of Novel Cancer Drug Combinations.
    Friedman AA; Xia Y; Trippa L; Le LP; Igras V; Frederick DT; Wargo JA; Tanabe KK; Lawrence DP; Neuberg DS; Flaherty KT; Fisher DE
    Clin Cancer Res; 2017 Aug; 23(16):4680-4692. PubMed ID: 28446504
    [No Abstract]   [Full Text] [Related]  

  • 18. TranSynergy: Mechanism-driven interpretable deep neural network for the synergistic prediction and pathway deconvolution of drug combinations.
    Liu Q; Xie L
    PLoS Comput Biol; 2021 Feb; 17(2):e1008653. PubMed ID: 33577560
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Drug resistance of BRAF-mutant melanoma: Review of up-to-date mechanisms of action and promising targeted agents.
    Rossi A; Roberto M; Panebianco M; Botticelli A; Mazzuca F; Marchetti P
    Eur J Pharmacol; 2019 Nov; 862():172621. PubMed ID: 31446019
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Antitumor activity of the selective pan-RAF inhibitor TAK-632 in BRAF inhibitor-resistant melanoma.
    Nakamura A; Arita T; Tsuchiya S; Donelan J; Chouitar J; Carideo E; Galvin K; Okaniwa M; Ishikawa T; Yoshida S
    Cancer Res; 2013 Dec; 73(23):7043-55. PubMed ID: 24121489
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 23.