312 related articles for article (PubMed ID: 30821197)
1. BCL11A Down-Regulation Induces γ-Globin in Human β-Thalassemia Major Erythroid Cells.
Li J; Lai Y; Shi L
Hemoglobin; 2018 Jul; 42(4):225-230. PubMed ID: 30821197
[TBL] [Abstract][Full Text] [Related]
2. SOX6 Downregulation Induces
Li J; Lai Y; Luo J; Luo L; Liu R; Liu Z; Zhao W
Biomed Res Int; 2017; 2017():9496058. PubMed ID: 29333458
[TBL] [Abstract][Full Text] [Related]
3. Human fetal hemoglobin expression is regulated by the developmental stage-specific repressor BCL11A.
Sankaran VG; Menne TF; Xu J; Akie TE; Lettre G; Van Handel B; Mikkola HK; Hirschhorn JN; Cantor AB; Orkin SH
Science; 2008 Dec; 322(5909):1839-42. PubMed ID: 19056937
[TBL] [Abstract][Full Text] [Related]
4. Featured Article: Modulation of fetal hemoglobin in hereditary persistence of fetal hemoglobin deletion type-2, compared to Sicilian δβ-thalassemia, by BCL11A and SOX6-targeting microRNAs.
Fornari TA; Lanaro C; Albuquerque DM; Ferreira R; Costa FF
Exp Biol Med (Maywood); 2017 Feb; 242(3):267-274. PubMed ID: 27591578
[TBL] [Abstract][Full Text] [Related]
5. MicroRNA-486-3p regulates γ-globin expression in human erythroid cells by directly modulating BCL11A.
Lulli V; Romania P; Morsilli O; Cianciulli P; Gabbianelli M; Testa U; Giuliani A; Marziali G
PLoS One; 2013; 8(4):e60436. PubMed ID: 23593217
[TBL] [Abstract][Full Text] [Related]
6. Acyclovir induces fetal hemoglobin via downregulation of γ-globin repressors, BCL11A and SOX6 trans-acting factors.
Ali H; Khan F; Ghulam Musharraf S
Biochem Pharmacol; 2021 Aug; 190():114612. PubMed ID: 34010599
[TBL] [Abstract][Full Text] [Related]
7. Targeted deletion of BCL11A gene by CRISPR-Cas9 system for fetal hemoglobin reactivation: A promising approach for gene therapy of beta thalassemia disease.
Khosravi MA; Abbasalipour M; Concordet JP; Berg JV; Zeinali S; Arashkia A; Azadmanesh K; Buch T; Karimipoor M
Eur J Pharmacol; 2019 Jul; 854():398-405. PubMed ID: 31039344
[TBL] [Abstract][Full Text] [Related]
8. Pharmacological Induction of Human Fetal Globin Gene in Hydroxyurea-Resistant Primary Adult Erythroid Cells.
Chou YC; Chen RL; Lai ZS; Song JS; Chao YS; Shen CK
Mol Cell Biol; 2015 Jul; 35(14):2541-53. PubMed ID: 25986606
[TBL] [Abstract][Full Text] [Related]
9. Induction of adult levels of β-globin in human erythroid cells that intrinsically express embryonic or fetal globin by transduction with KLF1 and BCL11A-XL.
Trakarnsanga K; Wilson MC; Lau W; Singleton BK; Parsons SF; Sakuntanaga P; Kurita R; Nakamura Y; Anstee DJ; Frayne J
Haematologica; 2014 Nov; 99(11):1677-85. PubMed ID: 25107887
[TBL] [Abstract][Full Text] [Related]
10. Plastrum testudinis induces γ-globin gene expression through epigenetic histone modifications within the γ-globin gene promoter via activation of the p38 MAPK signaling pathway.
Qian X; Chen J; Zhao D; Guo L; Qian X
Int J Mol Med; 2013 Jun; 31(6):1418-28. PubMed ID: 23588991
[TBL] [Abstract][Full Text] [Related]
11. miR-30a regulates γ-globin expression in erythoid precursors of intermedia thalassemia through targeting BCL11A.
Gholampour MA; Asadi M; Naderi M; Azarkeivan A; Soleimani M; Atashi A
Mol Biol Rep; 2020 May; 47(5):3909-3918. PubMed ID: 32406020
[TBL] [Abstract][Full Text] [Related]
12. Direct Promoter Repression by BCL11A Controls the Fetal to Adult Hemoglobin Switch.
Liu N; Hargreaves VV; Zhu Q; Kurland JV; Hong J; Kim W; Sher F; Macias-Trevino C; Rogers JM; Kurita R; Nakamura Y; Yuan GC; Bauer DE; Xu J; Bulyk ML; Orkin SH
Cell; 2018 Apr; 173(2):430-442.e17. PubMed ID: 29606353
[TBL] [Abstract][Full Text] [Related]
13. Compensated variability in the expression of globin-related genes in erythroblasts generated ex vivo from different donors.
Varricchio L; Fabucci ME; Alfani E; Godbold J; Migliaccio AR
Transfusion; 2010 Mar; 50(3):672-84. PubMed ID: 19891622
[TBL] [Abstract][Full Text] [Related]
14. The Novel Role of the B-Cell Lymphoma/Leukemia 11A (BCL11A) Gene in β-Thalassaemia Treatment.
Mahmoud Ahmed NH; Lai MI
Cardiovasc Hematol Disord Drug Targets; 2023; 22(4):226-236. PubMed ID: 36734897
[TBL] [Abstract][Full Text] [Related]
15. Tenofovir disoproxil fumarate induces fetal hemoglobin production in K562 cells and β-YAC transgenic mice: A therapeutic approach for γ-globin induction.
Khan F; Ali H; Musharraf SG
Exp Cell Res; 2020 Sep; 394(2):112168. PubMed ID: 32653411
[TBL] [Abstract][Full Text] [Related]
16. IOX1 Fails to Reduce α-Globin and Mediates γ-Globin Silencing in Adult β
Khamphikham P; Wongborisuth C; Pornprasert S; Tantiworawit A; Tangprasittipap A; Songdej D; Hongeng S
Exp Hematol; 2022; 112-113():9-14.e7. PubMed ID: 35839944
[TBL] [Abstract][Full Text] [Related]
17. SIRT1 activates the expression of fetal hemoglobin genes.
Dai Y; Chen T; Ijaz H; Cho EH; Steinberg MH
Am J Hematol; 2017 Nov; 92(11):1177-1186. PubMed ID: 28776729
[TBL] [Abstract][Full Text] [Related]
18. Reciprocal regulation of γ-globin expression by exo-miRNAs: Relevance to γ-globin silencing in β-thalassemia major.
Sun KT; Huang YN; Palanisamy K; Chang SS; Wang IK; Wu KH; Chen P; Peng CT; Li CY
Sci Rep; 2017 Mar; 7(1):202. PubMed ID: 28303002
[TBL] [Abstract][Full Text] [Related]
19. Transcriptional regulators Myb and BCL11A interplay with DNA methyltransferase 1 in developmental silencing of embryonic and fetal β-like globin genes.
Roosjen M; McColl B; Kao B; Gearing LJ; Blewitt ME; Vadolas J
FASEB J; 2014 Apr; 28(4):1610-20. PubMed ID: 24371119
[TBL] [Abstract][Full Text] [Related]
20. BCL11A-targeted γ-globin gene induction by triterpenoid glycosides of Fagonia indica: A preclinical scientific validation of indigenous herb for the treatment of β-hemoglobinopathies.
Iftikhar F; Khan MBN; Tehreem S; Kanwal N; Musharraf SG
Bioorg Chem; 2023 Nov; 140():106768. PubMed ID: 37586133
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]