295 related articles for article (PubMed ID: 30821702)
1. Journey to the center of the protein: allostery from multitemperature multiconformer X-ray crystallography.
Keedy DA
Acta Crystallogr D Struct Biol; 2019 Feb; 75(Pt 2):123-137. PubMed ID: 30821702
[TBL] [Abstract][Full Text] [Related]
2. An expanded allosteric network in PTP1B by multitemperature crystallography, fragment screening, and covalent tethering.
Keedy DA; Hill ZB; Biel JT; Kang E; Rettenmaier TJ; Brandão-Neto J; Pearce NM; von Delft F; Wells JA; Fraser JS
Elife; 2018 Jun; 7():. PubMed ID: 29877794
[TBL] [Abstract][Full Text] [Related]
3. Mapping the conformational landscape of a dynamic enzyme by multitemperature and XFEL crystallography.
Keedy DA; Kenner LR; Warkentin M; Woldeyes RA; Hopkins JB; Thompson MC; Brewster AS; Van Benschoten AH; Baxter EL; Uervirojnangkoorn M; McPhillips SE; Song J; Alonso-Mori R; Holton JM; Weis WI; Brunger AT; Soltis SM; Lemke H; Gonzalez A; Sauter NK; Cohen AE; van den Bedem H; Thorne RE; Fraser JS
Elife; 2015 Sep; 4():. PubMed ID: 26422513
[TBL] [Abstract][Full Text] [Related]
4. Ligand binding remodels protein side-chain conformational heterogeneity.
Wankowicz SA; de Oliveira SH; Hogan DW; van den Bedem H; Fraser JS
Elife; 2022 Mar; 11():. PubMed ID: 35312477
[TBL] [Abstract][Full Text] [Related]
5. Refinement of multiconformer ensemble models from multi-temperature X-ray diffraction data.
Du S; Wankowicz SA; Yabukarski F; Doukov T; Herschlag D; Fraser JS
Methods Enzymol; 2023; 688():223-254. PubMed ID: 37748828
[TBL] [Abstract][Full Text] [Related]
6. Integrated description of protein dynamics from room-temperature X-ray crystallography and NMR.
Fenwick RB; van den Bedem H; Fraser JS; Wright PE
Proc Natl Acad Sci U S A; 2014 Jan; 111(4):E445-54. PubMed ID: 24474795
[TBL] [Abstract][Full Text] [Related]
7. qFit 3: Protein and ligand multiconformer modeling for X-ray crystallographic and single-particle cryo-EM density maps.
Riley BT; Wankowicz SA; de Oliveira SHP; van Zundert GCP; Hogan DW; Fraser JS; Keedy DA; van den Bedem H
Protein Sci; 2021 Jan; 30(1):270-285. PubMed ID: 33210433
[TBL] [Abstract][Full Text] [Related]
8. Exposing Hidden Alternative Backbone Conformations in X-ray Crystallography Using qFit.
Keedy DA; Fraser JS; van den Bedem H
PLoS Comput Biol; 2015 Oct; 11(10):e1004507. PubMed ID: 26506617
[TBL] [Abstract][Full Text] [Related]
9. Room-temperature serial synchrotron crystallography of the human phosphatase PTP1B.
Sharma S; Ebrahim A; Keedy DA
Acta Crystallogr F Struct Biol Commun; 2023 Jan; 79(Pt 1):23-30. PubMed ID: 36598353
[TBL] [Abstract][Full Text] [Related]
10. Refinement of Multiconformer Ensemble Models from Multi-temperature X-ray Diffraction Data.
Du S; Wankowicz SA; Yabukarski F; Doukov T; Herschlag D; Fraser JS
bioRxiv; 2023 May; ():. PubMed ID: 37205593
[TBL] [Abstract][Full Text] [Related]
11. Computation of conformational coupling in allosteric proteins.
Kidd BA; Baker D; Thomas WE
PLoS Comput Biol; 2009 Aug; 5(8):e1000484. PubMed ID: 19714199
[TBL] [Abstract][Full Text] [Related]
12. Mechanisms for allosteric activation of protease DegS by ligand binding and oligomerization as revealed from molecular dynamics simulations.
Lu C; Stock G; Knecht V
Proteins; 2016 Nov; 84(11):1690-1705. PubMed ID: 27556733
[TBL] [Abstract][Full Text] [Related]
13. Fluctuations within folded proteins: implications for thermodynamic and allosteric regulation.
DuBay KH; Bowman GR; Geissler PL
Acc Chem Res; 2015 Apr; 48(4):1098-105. PubMed ID: 25688669
[TBL] [Abstract][Full Text] [Related]
14. Is allostery an intrinsic property of all dynamic proteins?
Gunasekaran K; Ma B; Nussinov R
Proteins; 2004 Nov; 57(3):433-43. PubMed ID: 15382234
[TBL] [Abstract][Full Text] [Related]
15. Sparse networks of directly coupled, polymorphic, and functional side chains in allosteric proteins.
Soltan Ghoraie L; Burkowski F; Zhu M
Proteins; 2015 Mar; 83(3):497-516. PubMed ID: 25545075
[TBL] [Abstract][Full Text] [Related]
16. Room-temperature crystallography reveals altered binding of small-molecule fragments to PTP1B.
Skaist Mehlman T; Biel JT; Azeem SM; Nelson ER; Hossain S; Dunnett L; Paterson NG; Douangamath A; Talon R; Axford D; Orins H; von Delft F; Keedy DA
Elife; 2023 Mar; 12():. PubMed ID: 36881464
[TBL] [Abstract][Full Text] [Related]
17. Allosteric nanobodies reveal the dynamic range and diverse mechanisms of G-protein-coupled receptor activation.
Staus DP; Strachan RT; Manglik A; Pani B; Kahsai AW; Kim TH; Wingler LM; Ahn S; Chatterjee A; Masoudi A; Kruse AC; Pardon E; Steyaert J; Weis WI; Prosser RS; Kobilka BK; Costa T; Lefkowitz RJ
Nature; 2016 Jul; 535(7612):448-52. PubMed ID: 27409812
[TBL] [Abstract][Full Text] [Related]
18. qFit-ligand Reveals Widespread Conformational Heterogeneity of Drug-Like Molecules in X-Ray Electron Density Maps.
van Zundert GCP; Hudson BM; de Oliveira SHP; Keedy DA; Fonseca R; Heliou A; Suresh P; Borrelli K; Day T; Fraser JS; van den Bedem H
J Med Chem; 2018 Dec; 61(24):11183-11198. PubMed ID: 30457858
[TBL] [Abstract][Full Text] [Related]
19. The ensemble nature of allostery.
Motlagh HN; Wrabl JO; Li J; Hilser VJ
Nature; 2014 Apr; 508(7496):331-9. PubMed ID: 24740064
[TBL] [Abstract][Full Text] [Related]
20. Modulation of global low-frequency motions underlies allosteric regulation: demonstration in CRP/FNR family transcription factors.
Rodgers TL; Townsend PD; Burnell D; Jones ML; Richards SA; McLeish TC; Pohl E; Wilson MR; Cann MJ
PLoS Biol; 2013 Sep; 11(9):e1001651. PubMed ID: 24058293
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]