172 related articles for article (PubMed ID: 30821899)
21. Novel Independent Trans- and Cis-Genetic Variants Associated with CYP2D6 Expression and Activity in Human Livers.
Smith D; He B; Shi J; Zhu HJ; Wang X
Drug Metab Dispos; 2024 Jan; 52(2):143-152. PubMed ID: 38050015
[TBL] [Abstract][Full Text] [Related]
22. Three new alternative splicing variants of human cytochrome P450 2D6 mRNA in human extratumoral liver tissue.
Zhuge J; Yu YN
World J Gastroenterol; 2004 Nov; 10(22):3356-60. PubMed ID: 15484318
[TBL] [Abstract][Full Text] [Related]
23. Only truncated, not complete cytochrome p450 2D6 RNA transcript and no detectable enzyme activity are expressed in human lymphocytes.
McConnachie LA; Phillips B; Bajpai M; Shen DD; Ho RJ
Drug Metab Dispos; 2003 Sep; 31(9):1103-7. PubMed ID: 12920165
[TBL] [Abstract][Full Text] [Related]
24. Functional and structural characterisation of common cytochrome P450 2D6 allelic variants-roles of Pro34 and Thr107 in catalysis and inhibition.
Dong AN; Ahemad N; Pan Y; Palanisamy UD; Yiap BC; Ong CE
Naunyn Schmiedebergs Arch Pharmacol; 2019 Aug; 392(8):1015-1029. PubMed ID: 31025144
[TBL] [Abstract][Full Text] [Related]
25. Inter-individual variability of in vivo CYP2D6 activity in different genotypes.
Chiba K; Kato M; Ito T; Suwa T; Sugiyama Y
Drug Metab Pharmacokinet; 2012; 27(4):405-13. PubMed ID: 22277677
[TBL] [Abstract][Full Text] [Related]
26. Polymorphisms and phenotypic analysis of cytochrome P450 2D6 in the Tibetan population.
Jin TB; Ma LF; Zhang JY; Yuan DY; Sun Q; Zong TY; Geng TT; Cui YL; Kang LL; Chen C
Gene; 2013 Sep; 527(1):360-5. PubMed ID: 23644254
[TBL] [Abstract][Full Text] [Related]
27. Genetic polymorphism of cytochrome P450 2D6 determines oestrogen receptor activity of the major infertility drug clomiphene via its active metabolites.
Mürdter TE; Kerb R; Turpeinen M; Schroth W; Ganchev B; Böhmer GM; Igel S; Schaeffeler E; Zanger U; Brauch H; Schwab M
Hum Mol Genet; 2012 Mar; 21(5):1145-54. PubMed ID: 22108178
[TBL] [Abstract][Full Text] [Related]
28. V79 Chinese hamster cells genetically engineered for polymorphic cytochrome P450 2D6 and their predictive value for humans.
Krebsfaenger N; Mürdter TE; Zanger UM; Eichelbaum MF; Doehmer J
ALTEX; 2003; 20(3):143-54. PubMed ID: 12947487
[TBL] [Abstract][Full Text] [Related]
29. Evaluation of CYP2D6 Protein Expression and Activity in the Small Intestine to Determine Its Metabolic Capability in the Japanese Population.
Kawakami M; Takenoshita-Nakaya S; Takeba Y; Nishimura Y; Oda M; Watanabe M; Ohta Y; Kobayashi S; Ohtsubo T; Kobayashi S; Uchida N; Matsumoto N
Biol Pharm Bull; 2017 Sep; 40(9):1344-1351. PubMed ID: 28626197
[TBL] [Abstract][Full Text] [Related]
30. Expression in human prostate of drug- and carcinogen-metabolizing enzymes: association with prostate cancer risk.
Agúndez JA; Martínez C; Olivera M; Gallardo L; Ladero JM; Rosado C; Prados J; Rodriguez-Molina J; Resel L; Benítez J
Br J Cancer; 1998 Nov; 78(10):1361-7. PubMed ID: 9823980
[TBL] [Abstract][Full Text] [Related]
31. Computational predictions of the site of metabolism of cytochrome P450 2D6 substrates: comparative analysis, molecular docking, bioactivation and toxicological implications.
Ford KA; Ryslik G; Sodhi J; Halladay J; Diaz D; Dambach D; Masuda M
Drug Metab Rev; 2015 Aug; 47(3):291-319. PubMed ID: 26024250
[TBL] [Abstract][Full Text] [Related]
32. The importance of heterogeneous nuclear ribonucleoprotein K on cytochrome P450 2D2 gene regulation: its binding is reduced in Dark Agouti rats.
Sakai N; Sakamoto KQ; Fujita S; Ishizuka M
Drug Metab Dispos; 2009 Aug; 37(8):1703-10. PubMed ID: 19420131
[TBL] [Abstract][Full Text] [Related]
33. Comparative cytochrome P450 -1A1, -2A6, -2B6, -2C, -2D6, -2E1, -3A5 and -4B1 expressions in human larynx tissue analysed at mRNA level.
Sarikaya D; Bilgen C; Kamataki T; Topcu Z
Biopharm Drug Dispos; 2006 Nov; 27(8):353-9. PubMed ID: 16894644
[TBL] [Abstract][Full Text] [Related]
34. Marsdenia tenacissima extract inhibits gefitinib metabolism in vitro by interfering with human hepatic CYP3A4 and CYP2D6 enzymes.
Han SY; Zhao HY; Zhou N; Zhou F; Li PP
J Ethnopharmacol; 2014; 151(1):210-7. PubMed ID: 24157377
[TBL] [Abstract][Full Text] [Related]
35. Discriminative quantification of cytochrome P4502D6 and 2D7/8 pseudogene expression by TaqMan real-time reverse transcriptase polymerase chain reaction.
Endrizzi K; Fischer J; Klein K; Schwab M; Nüssler A; Neuhaus P; Eichelbaum M; Zanger UM
Anal Biochem; 2002 Jan; 300(2):121-31. PubMed ID: 11779102
[TBL] [Abstract][Full Text] [Related]
36. Genetic polymorphisms of cytochrome P450 2D6 (CYP2D6): clinical consequences, evolutionary aspects and functional diversity.
Ingelman-Sundberg M
Pharmacogenomics J; 2005; 5(1):6-13. PubMed ID: 15492763
[TBL] [Abstract][Full Text] [Related]
37. Substrate specific metabolism by polymorphic cytochrome P450 2D6 alleles.
Bogni A; Monshouwer M; Moscone A; Hidestrand M; Ingelman-Sundberg M; Hartung T; Coecke S
Toxicol In Vitro; 2005 Aug; 19(5):621-9. PubMed ID: 15893449
[TBL] [Abstract][Full Text] [Related]
38. Cytochrome P450 2D6 and Parkinson's Disease: Polymorphism, Metabolic Role, Risk and Protection.
Ur Rasheed MS; Mishra AK; Singh MP
Neurochem Res; 2017 Dec; 42(12):3353-3361. PubMed ID: 28871472
[TBL] [Abstract][Full Text] [Related]
39. Functional characterization of 17 CYP2D6 allelic variants (CYP2D6.2, 10, 14A-B, 18, 27, 36, 39, 47-51, 53-55, and 57).
Sakuyama K; Sasaki T; Ujiie S; Obata K; Mizugaki M; Ishikawa M; Hiratsuka M
Drug Metab Dispos; 2008 Dec; 36(12):2460-7. PubMed ID: 18784265
[TBL] [Abstract][Full Text] [Related]
40. Human NADPH-P450 oxidoreductase modulates the level of cytochrome P450 CYP2D6 holoprotein via haem oxygenase-dependent and -independent pathways.
Ding S; Yao D; Deeni YY; Burchell B; Wolf CR; Friedberg T
Biochem J; 2001 Jun; 356(Pt 2):613-9. PubMed ID: 11368792
[TBL] [Abstract][Full Text] [Related]
[Previous] [Next] [New Search]
