303 related articles for article (PubMed ID: 30822690)
21. Esculetin induces antiproliferative and apoptotic response in pancreatic cancer cells by directly binding to KEAP1.
Arora R; Sawney S; Saini V; Steffi C; Tiwari M; Saluja D
Mol Cancer; 2016 Oct; 15(1):64. PubMed ID: 27756327
[TBL] [Abstract][Full Text] [Related]
22. Structural insights into the multiple binding modes of Dimethyl Fumarate (DMF) and its analogs to the Kelch domain of Keap1.
Unni S; Deshmukh P; Krishnappa G; Kommu P; Padmanabhan B
FEBS J; 2021 Mar; 288(5):1599-1613. PubMed ID: 32672401
[TBL] [Abstract][Full Text] [Related]
23. Loss of Kelch-like ECH-associated protein 1 function in prostate cancer cells causes chemoresistance and radioresistance and promotes tumor growth.
Zhang P; Singh A; Yegnasubramanian S; Esopi D; Kombairaju P; Bodas M; Wu H; Bova SG; Biswal S
Mol Cancer Ther; 2010 Feb; 9(2):336-46. PubMed ID: 20124447
[TBL] [Abstract][Full Text] [Related]
24. Monoacidic Inhibitors of the Kelch-like ECH-Associated Protein 1: Nuclear Factor Erythroid 2-Related Factor 2 (KEAP1:NRF2) Protein-Protein Interaction with High Cell Potency Identified by Fragment-Based Discovery.
Davies TG; Wixted WE; Coyle JE; Griffiths-Jones C; Hearn K; McMenamin R; Norton D; Rich SJ; Richardson C; Saxty G; Willems HM; Woolford AJ; Cottom JE; Kou JP; Yonchuk JG; Feldser HG; Sanchez Y; Foley JP; Bolognese BJ; Logan G; Podolin PL; Yan H; Callahan JF; Heightman TD; Kerns JK
J Med Chem; 2016 Apr; 59(8):3991-4006. PubMed ID: 27031670
[TBL] [Abstract][Full Text] [Related]
25. ATDC binds to KEAP1 to drive NRF2-mediated tumorigenesis and chemoresistance in pancreatic cancer.
Purohit V; Wang L; Yang H; Li J; Ney GM; Gumkowski ER; Vaidya AJ; Wang A; Bhardwaj A; Zhao E; Dolgalev I; Zamperone A; Abel EV; Magliano MPD; Crawford HC; Diolaiti D; Papagiannakopoulos TY; Lyssiotis CA; Simeone DM
Genes Dev; 2021 Feb; 35(3-4):218-233. PubMed ID: 33446568
[TBL] [Abstract][Full Text] [Related]
26. Activation of KEAP1/NRF2 stress signaling involved in the molecular basis of hemin-induced cytotoxicity in human pro-erythroid K562 cells.
Georgiou-Siafis SK; Tsiftsoglou AS
Biochem Pharmacol; 2020 May; 175():113900. PubMed ID: 32156661
[TBL] [Abstract][Full Text] [Related]
27. Increased Nrf2 activation in livers from Keap1-knockdown mice increases expression of cytoprotective genes that detoxify electrophiles more than those that detoxify reactive oxygen species.
Reisman SA; Yeager RL; Yamamoto M; Klaassen CD
Toxicol Sci; 2009 Mar; 108(1):35-47. PubMed ID: 19129213
[TBL] [Abstract][Full Text] [Related]
28. Gallic acid, a natural polyphenol, protects against tert-butyl hydroperoxide- induced hepatotoxicity by activating ERK-Nrf2-Keap1-mediated antioxidative response.
Feng RB; Wang Y; He C; Yang Y; Wan JB
Food Chem Toxicol; 2018 Sep; 119():479-488. PubMed ID: 29066411
[TBL] [Abstract][Full Text] [Related]
29. Emerging Substrate Proteins of Kelch-like ECH Associated Protein 1 (Keap1) and Potential Challenges for the Development of Small-Molecule Inhibitors of the Keap1-Nuclear Factor Erythroid 2-Related Factor 2 (Nrf2) Protein-Protein Interaction.
Zhang Y; Shi Z; Zhou Y; Xiao Q; Wang H; Peng Y
J Med Chem; 2020 Aug; 63(15):7986-8002. PubMed ID: 32233486
[TBL] [Abstract][Full Text] [Related]
30. Gene-expression signature regulated by the KEAP1-NRF2-CUL3 axis is associated with a poor prognosis in head and neck squamous cell cancer.
Namani A; Matiur Rahaman M; Chen M; Tang X
BMC Cancer; 2018 Jan; 18(1):46. PubMed ID: 29306329
[TBL] [Abstract][Full Text] [Related]
31. Natural phenylethanoid glycosides isolated from Callicarpa kwangtungensis suppressed lipopolysaccharide-mediated inflammatory response via activating Keap1/Nrf2/HO-1 pathway in RAW 264.7 macrophages cell.
Wu A; Yang Z; Huang Y; Yuan H; Lin C; Wang T; Zhao Z; Zhou Y; Zhu C
J Ethnopharmacol; 2020 Aug; 258():112857. PubMed ID: 32298752
[TBL] [Abstract][Full Text] [Related]
32. The Role of NRF2/KEAP1 Signaling Pathway in Cancer Metabolism.
Song MY; Lee DY; Chun KS; Kim EH
Int J Mol Sci; 2021 Apr; 22(9):. PubMed ID: 33922165
[TBL] [Abstract][Full Text] [Related]
33. New insights into the mechanism of Keap1-Nrf2 interaction based on cancer-associated mutations.
Cheng L; Wang H; Li S; Liu Z; Wang C
Life Sci; 2021 Oct; 282():119791. PubMed ID: 34229009
[TBL] [Abstract][Full Text] [Related]
34. p62 promotes proliferation, apoptosis‑resistance and invasion of prostate cancer cells through the Keap1/Nrf2/ARE axis.
Jiang G; Liang X; Huang Y; Lan Z; Zhang Z; Su Z; Fang Z; Lai Y; Yao W; Liu T; Hu L; Wang F; Huang H; Liu L; Jiang X
Oncol Rep; 2020 May; 43(5):1547-1557. PubMed ID: 32323805
[TBL] [Abstract][Full Text] [Related]
35. [Overexpression of Keap1 inhibits the cell proliferation and metastasis and overcomes the drug resistance in human lung cancer A549 cells].
Weng X; Yan YY; Tong YH; Fan Y; Zeng JM; Wang LL; Lin NM
Zhonghua Zhong Liu Za Zhi; 2016 Jun; 38(6):404-10. PubMed ID: 27346396
[TBL] [Abstract][Full Text] [Related]
36. Overexpression of miR-200a protects cardiomyocytes against hypoxia-induced apoptosis by modulating the kelch-like ECH-associated protein 1-nuclear factor erythroid 2-related factor 2 signaling axis.
Sun X; Zuo H; Liu C; Yang Y
Int J Mol Med; 2016 Oct; 38(4):1303-11. PubMed ID: 27573160
[TBL] [Abstract][Full Text] [Related]
37. Molecular mechanisms for the regulation of Nrf2-mediated cell proliferation in non-small-cell lung cancers.
Yamadori T; Ishii Y; Homma S; Morishima Y; Kurishima K; Itoh K; Yamamoto M; Minami Y; Noguchi M; Hizawa N
Oncogene; 2012 Nov; 31(45):4768-77. PubMed ID: 22249257
[TBL] [Abstract][Full Text] [Related]
38. Continuous activation of Nrf2 and its target antioxidant enzymes leads to arsenite-induced malignant transformation of human bronchial epithelial cells.
Yang X; Wang D; Ma Y; Xu X; Zhu Z; Wang X; Deng H; Li C; Chen M; Tong J; Yamanaka K; An Y
Toxicol Appl Pharmacol; 2015 Dec; 289(2):231-9. PubMed ID: 26420645
[TBL] [Abstract][Full Text] [Related]
39. TRIM16 protects from OGD/R-induced oxidative stress in cultured hippocampal neurons by enhancing Nrf2/ARE antioxidant signaling via downregulation of Keap1.
Ren X; Yu J; Guo L; Ma H
Exp Cell Res; 2020 Jun; 391(1):111988. PubMed ID: 32251645
[TBL] [Abstract][Full Text] [Related]
40. CPUY192018, a potent inhibitor of the Keap1-Nrf2 protein-protein interaction, alleviates renal inflammation in mice by restricting oxidative stress and NF-κB activation.
Lu MC; Zhao J; Liu YT; Liu T; Tao MM; You QD; Jiang ZY
Redox Biol; 2019 Sep; 26():101266. PubMed ID: 31279986
[TBL] [Abstract][Full Text] [Related]
[Previous] [Next] [New Search]
