127 related articles for article (PubMed ID: 30827110)
1. Discovery of Isaindigotone Derivatives as Novel Bloom's Syndrome Protein (BLM) Helicase Inhibitors That Disrupt the BLM/DNA Interactions and Regulate the Homologous Recombination Repair.
Yin QK; Wang CX; Wang YQ; Guo QL; Zhang ZL; Ou TM; Huang SL; Li D; Wang HG; Tan JH; Chen SB; Huang ZS
J Med Chem; 2019 Mar; 62(6):3147-3162. PubMed ID: 30827110
[TBL] [Abstract][Full Text] [Related]
2. BLM helicase regulates DNA repair by counteracting RAD51 loading at DNA double-strand break sites.
Patel DS; Misenko SM; Her J; Bunting SF
J Cell Biol; 2017 Nov; 216(11):3521-3534. PubMed ID: 28912125
[TBL] [Abstract][Full Text] [Related]
3. Design, Synthesis, and Evaluation of New Quinazolinone Derivatives that Inhibit Bloom Syndrome Protein (BLM) Helicase, Trigger DNA Damage at the Telomere Region, and Synergize with PARP Inhibitors.
Wang CX; Zhang ZL; Yin QK; Tu JL; Wang JE; Xu YH; Rao Y; Ou TM; Huang SL; Li D; Wang HG; Li QJ; Tan JH; Chen SB; Huang ZS
J Med Chem; 2020 Sep; 63(17):9752-9772. PubMed ID: 32697083
[TBL] [Abstract][Full Text] [Related]
4. Design, synthesis and evaluation of N3-substituted quinazolinone derivatives as potential Bloom's Syndrome protein (BLM) helicase inhibitor for sensitization treatment of colorectal cancer.
Tu JL; Wu BH; Wu HB; Wang JE; Zhang ZL; Gao KY; Zhang LX; Chen QR; Zhou YC; Tan JH; Huang ZS; Chen SB
Eur J Med Chem; 2023 Jan; 246():114944. PubMed ID: 36459756
[TBL] [Abstract][Full Text] [Related]
5. Human exonuclease 1 and BLM helicase interact to resect DNA and initiate DNA repair.
Nimonkar AV; Ozsoy AZ; Genschel J; Modrich P; Kowalczykowski SC
Proc Natl Acad Sci U S A; 2008 Nov; 105(44):16906-11. PubMed ID: 18971343
[TBL] [Abstract][Full Text] [Related]
6. Bloom syndrome helicase stimulates RAD51 DNA strand exchange activity through a novel mechanism.
Bugreev DV; Mazina OM; Mazin AV
J Biol Chem; 2009 Sep; 284(39):26349-59. PubMed ID: 19632996
[TBL] [Abstract][Full Text] [Related]
7. Scaffolding protein SPIDR/KIAA0146 connects the Bloom syndrome helicase with homologous recombination repair.
Wan L; Han J; Liu T; Dong S; Xie F; Chen H; Huang J
Proc Natl Acad Sci U S A; 2013 Jun; 110(26):10646-51. PubMed ID: 23509288
[TBL] [Abstract][Full Text] [Related]
8. A small molecule inhibitor of the BLM helicase modulates chromosome stability in human cells.
Nguyen GH; Dexheimer TS; Rosenthal AS; Chu WK; Singh DK; Mosedale G; Bachrati CZ; Schultz L; Sakurai M; Savitsky P; Abu M; McHugh PJ; Bohr VA; Harris CC; Jadhav A; Gileadi O; Maloney DJ; Simeonov A; Hickson ID
Chem Biol; 2013 Jan; 20(1):55-62. PubMed ID: 23352139
[TBL] [Abstract][Full Text] [Related]
9. SUMO modification regulates BLM and RAD51 interaction at damaged replication forks.
Ouyang KJ; Woo LL; Zhu J; Huo D; Matunis MJ; Ellis NA
PLoS Biol; 2009 Dec; 7(12):e1000252. PubMed ID: 19956565
[TBL] [Abstract][Full Text] [Related]
10. A new development in DNA repair modulation: discovery of a BLM helicase inhibitor.
Banerjee T; Aggarwal M; Brosh RM
Cell Cycle; 2013 Mar; 12(5):713-4. PubMed ID: 23422862
[No Abstract] [Full Text] [Related]
11. Role for RIF1-interacting partner DDX1 in BLM recruitment to DNA double-strand breaks.
Li L; Poon HY; Hildebrandt MR; Monckton EA; Germain DR; Fahlman RP; Godbout R
DNA Repair (Amst); 2017 Jul; 55():47-63. PubMed ID: 28544931
[TBL] [Abstract][Full Text] [Related]
12. Critical interaction domains between bloom syndrome protein and RAD51.
Bergeron KL; Murphy EL; Brown LW; Almeida KH
Protein J; 2011 Jan; 30(1):1-8. PubMed ID: 21113733
[TBL] [Abstract][Full Text] [Related]
13. Bloom DNA helicase facilitates homologous recombination between diverged homologous sequences.
Kikuchi K; Abdel-Aziz HI; Taniguchi Y; Yamazoe M; Takeda S; Hirota K
J Biol Chem; 2009 Sep; 284(39):26360-7. PubMed ID: 19661064
[TBL] [Abstract][Full Text] [Related]
14. MRN complex-dependent recruitment of ubiquitylated BLM helicase to DSBs negatively regulates DNA repair pathways.
Tripathi V; Agarwal H; Priya S; Batra H; Modi P; Pandey M; Saha D; Raghavan SC; Sengupta S
Nat Commun; 2018 Mar; 9(1):1016. PubMed ID: 29523790
[TBL] [Abstract][Full Text] [Related]
15. Genomic instability and cancer: lessons from analysis of Bloom's syndrome.
Payne M; Hickson ID
Biochem Soc Trans; 2009 Jun; 37(Pt 3):553-9. PubMed ID: 19442250
[TBL] [Abstract][Full Text] [Related]
16. Single-molecule visualization of human BLM helicase as it acts upon double- and single-stranded DNA substrates.
Xue C; Daley JM; Xue X; Steinfeld J; Kwon Y; Sung P; Greene EC
Nucleic Acids Res; 2019 Dec; 47(21):11225-11237. PubMed ID: 31544923
[TBL] [Abstract][Full Text] [Related]
17. Uncovering an allosteric mode of action for a selective inhibitor of human Bloom syndrome protein.
Chen X; Ali YI; Fisher CE; Arribas-Bosacoma R; Rajasekaran MB; Williams G; Walker S; Booth JR; Hudson JJ; Roe SM; Pearl LH; Ward SE; Pearl FM; Oliver AW
Elife; 2021 Mar; 10():. PubMed ID: 33647232
[TBL] [Abstract][Full Text] [Related]
18. A POLD3/BLM dependent pathway handles DSBs in transcribed chromatin upon excessive RNA:DNA hybrid accumulation.
Cohen S; Guenolé A; Lazar I; Marnef A; Clouaire T; Vernekar DV; Puget N; Rocher V; Arnould C; Aguirrebengoa M; Genais M; Firmin N; Shamanna RA; Mourad R; Bohr VA; Borde V; Legube G
Nat Commun; 2022 Apr; 13(1):2012. PubMed ID: 35440629
[TBL] [Abstract][Full Text] [Related]
19. The mismatch DNA repair heterodimer, hMSH2/6, regulates BLM helicase.
Yang Q; Zhang R; Wang XW; Linke SP; Sengupta S; Hickson ID; Pedrazzi G; Perrera C; Stagljar I; Littman SJ; Modrich P; Harris CC
Oncogene; 2004 May; 23(21):3749-56. PubMed ID: 15064730
[TBL] [Abstract][Full Text] [Related]
20. Inhibition of homologous recombination by treatment with BVDU (brivudin) or by RAD51 silencing increases chromosomal damage induced by bleomycin in mismatch repair-deficient tumour cells.
Vernole P; Muzi A; Volpi A; Dorio AS; Terrinoni A; Shah GM; Graziani G
Mutat Res; 2009 May; 664(1-2):39-47. PubMed ID: 19428379
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]