BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

406 related articles for article (PubMed ID: 30827998)

  • 21. Recent advances in the development of thioredoxin reductase inhibitors as anticancer agents.
    Liu Y; Li Y; Yu S; Zhao G
    Curr Drug Targets; 2012 Oct; 13(11):1432-44. PubMed ID: 22876886
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Sublethal concentrations of diverse gold compounds inhibit mammalian cytosolic thioredoxin reductase (TrxR1).
    Omata Y; Folan M; Shaw M; Messer RL; Lockwood PE; Hobbs D; Bouillaguet S; Sano H; Lewis JB; Wataha JC
    Toxicol In Vitro; 2006 Sep; 20(6):882-90. PubMed ID: 16510263
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Selective inhibition of endogenous antioxidants with Auranofin causes mitochondrial oxidative stress which can be countered by selenium supplementation.
    Radenkovic F; Holland O; Vanderlelie JJ; Perkins AV
    Biochem Pharmacol; 2017 Dec; 146():42-52. PubMed ID: 28947276
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Auranofin radiosensitizes tumor cells through targeting thioredoxin reductase and resulting overproduction of reactive oxygen species.
    Wang H; Bouzakoura S; de Mey S; Jiang H; Law K; Dufait I; Corbet C; Verovski V; Gevaert T; Feron O; Van den Berge D; Storme G; De Ridder M
    Oncotarget; 2017 May; 8(22):35728-35742. PubMed ID: 28415723
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Biochemical and structural characterizations of thioredoxin reductase selenoproteins of the parasitic filarial nematodes Brugia malayi and Onchocerca volvulus.
    Fata F; Gencheva R; Cheng Q; Lullo R; Ardini M; Silvestri I; Gabriele F; Ippoliti R; Bulman CA; Sakanari JA; Williams DL; Arnér ESJ; Angelucci F
    Redox Biol; 2022 May; 51():102278. PubMed ID: 35276442
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Cancer cell death induced by phosphine gold(I) compounds targeting thioredoxin reductase.
    Gandin V; Fernandes AP; Rigobello MP; Dani B; Sorrentino F; Tisato F; Björnstedt M; Bindoli A; Sturaro A; Rella R; Marzano C
    Biochem Pharmacol; 2010 Jan; 79(2):90-101. PubMed ID: 19665452
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Targeting thioredoxin reductase is a basis for cancer therapy by arsenic trioxide.
    Lu J; Chew EH; Holmgren A
    Proc Natl Acad Sci U S A; 2007 Jul; 104(30):12288-93. PubMed ID: 17640917
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Targeting redox homeostasis in rhabdomyosarcoma cells: GSH-depleting agents enhance auranofin-induced cell death.
    Habermann KJ; Grünewald L; van Wijk S; Fulda S
    Cell Death Dis; 2017 Oct; 8(10):e3067. PubMed ID: 28981107
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Simultaneous inhibition of glutathione- and thioredoxin-dependent metabolism is necessary to potentiate 17AAG-induced cancer cell killing via oxidative stress.
    Scarbrough PM; Mapuskar KA; Mattson DM; Gius D; Watson WH; Spitz DR
    Free Radic Biol Med; 2012 Jan; 52(2):436-43. PubMed ID: 22100505
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Transcriptional changes of proteins of the thioredoxin and glutathione systems in Acanthamoeba spp. under oxidative stress - an RNA approach.
    Köhsler M; Leitsch D; Loufouma Mbouaka A; Wekerle M; Walochnik J
    Parasite; 2022; 29():24. PubMed ID: 35532265
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Auranofin, an inhibitor of thioredoxin reductase, induces apoptosis in hepatocellular carcinoma Hep3B cells by generation of reactive oxygen species.
    Hwang-Bo H; Jeong JW; Han MH; Park C; Hong SH; Kim GY; Moon SK; Cheong J; Kim WJ; Yoo YH; Choi YH
    Gen Physiol Biophys; 2017 Apr; 36(2):117-128. PubMed ID: 28218611
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Metal- and Semimetal-Containing Inhibitors of Thioredoxin Reductase as Anticancer Agents.
    Gandin V; Fernandes AP
    Molecules; 2015 Jul; 20(7):12732-56. PubMed ID: 26184149
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Structure-activity relationships in a series of auranofin analogues showing remarkable antiproliferative properties.
    Landini I; Massai L; Cirri D; Gamberi T; Paoli P; Messori L; Mini E; Nobili S
    J Inorg Biochem; 2020 Jul; 208():111079. PubMed ID: 32497830
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Thioredoxin reductase inhibitors: a patent review.
    Zhang B; Zhang J; Peng S; Liu R; Li X; Hou Y; Han X; Fang J
    Expert Opin Ther Pat; 2017 May; 27(5):547-556. PubMed ID: 27977313
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Auranofin inactivates Trichomonas vaginalis thioredoxin reductase and is effective against trichomonads in vitro and in vivo.
    Hopper M; Yun JF; Zhou B; Le C; Kehoe K; Le R; Hill R; Jongeward G; Debnath A; Zhang L; Miyamoto Y; Eckmann L; Land KM; Wrischnik LA
    Int J Antimicrob Agents; 2016 Dec; 48(6):690-694. PubMed ID: 27839893
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Thioredoxin reductase inhibitors: updated patent review (2017-present).
    Chupakhin E; Krasavin M
    Expert Opin Ther Pat; 2021 Aug; 31(8):745-758. PubMed ID: 33666133
    [No Abstract]   [Full Text] [Related]  

  • 37. Inhibition of thioredoxin reductase by auranofin induces apoptosis in cisplatin-resistant human ovarian cancer cells.
    Marzano C; Gandin V; Folda A; Scutari G; Bindoli A; Rigobello MP
    Free Radic Biol Med; 2007 Mar; 42(6):872-81. PubMed ID: 17320769
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Targeting the Thioredoxin System as a Strategy for Cancer Therapy.
    Bian M; Fan R; Zhao S; Liu W
    J Med Chem; 2019 Aug; 62(16):7309-7321. PubMed ID: 30963763
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Differential redox sensitivity of cathepsin B and L holds the key to autophagy-apoptosis interplay after Thioredoxin reductase inhibition in nutritionally stressed SH-SY5Y cells.
    Nagakannan P; Eftekharpour E
    Free Radic Biol Med; 2017 Jul; 108():819-831. PubMed ID: 28478025
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Synthesis of naphthazarin derivatives and identification of novel thioredoxin reductase inhibitor as potential anticancer agent.
    Zhang J; Liu Y; Shi D; Hu G; Zhang B; Li X; Liu R; Han X; Yao X; Fang J
    Eur J Med Chem; 2017 Nov; 140():435-447. PubMed ID: 28987605
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 21.