198 related articles for article (PubMed ID: 30832206)
1. Design, Synthesis and Biological Evaluation of Isoxazole-Based CK1 Inhibitors Modified with Chiral Pyrrolidine Scaffolds.
Luxenburger A; Schmidt D; Ianes C; Pichlo C; Krüger M; von Drathen T; Brunstein E; Gainsford GJ; Baumann U; Knippschild U; Peifer C
Molecules; 2019 Mar; 24(5):. PubMed ID: 30832206
[TBL] [Abstract][Full Text] [Related]
2. C5-Iminosugar modification of casein kinase 1δ lead 3-(4-fluorophenyl)-5-isopropyl-4-(pyridin-4-yl)isoxazole promotes enhanced inhibitor affinity and selectivity.
von Drathen T; Ure EM; Kirschner S; Roth A; Meier L; Woolhouse AD; Cameron SA; Knippschild U; Peifer C; Luxenburger A
Arch Pharm (Weinheim); 2022 May; 355(5):e2100497. PubMed ID: 35174898
[TBL] [Abstract][Full Text] [Related]
3. 3,4-Diaryl-isoxazoles and -imidazoles as potent dual inhibitors of p38alpha mitogen activated protein kinase and casein kinase 1delta.
Peifer C; Abadleh M; Bischof J; Hauser D; Schattel V; Hirner H; Knippschild U; Laufer S
J Med Chem; 2009 Dec; 52(23):7618-30. PubMed ID: 19591487
[TBL] [Abstract][Full Text] [Related]
4. Optimized 4,5-Diarylimidazoles as Potent/Selective Inhibitors of Protein Kinase CK1δ and Their Structural Relation to p38α MAPK.
Halekotte J; Witt L; Ianes C; Krüger M; Bührmann M; Rauh D; Pichlo C; Brunstein E; Luxenburger A; Baumann U; Knippschild U; Bischof J; Peifer C
Molecules; 2017 Mar; 22(4):. PubMed ID: 28338621
[TBL] [Abstract][Full Text] [Related]
5. Discovery of Inhibitor of Wnt Production 2 (IWP-2) and Related Compounds As Selective ATP-Competitive Inhibitors of Casein Kinase 1 (CK1) δ/ε.
García-Reyes B; Witt L; Jansen B; Karasu E; Gehring T; Leban J; Henne-Bruns D; Pichlo C; Brunstein E; Baumann U; Wesseler F; Rathmer B; Schade D; Peifer C; Knippschild U
J Med Chem; 2018 May; 61(9):4087-4102. PubMed ID: 29630366
[TBL] [Abstract][Full Text] [Related]
6. Difluoro-dioxolo-benzoimidazol-benzamides as potent inhibitors of CK1δ and ε with nanomolar inhibitory activity on cancer cell proliferation.
Richter J; Bischof J; Zaja M; Kohlhof H; Othersen O; Vitt D; Alscher V; Pospiech I; García-Reyes B; Berg S; Leban J; Knippschild U
J Med Chem; 2014 Oct; 57(19):7933-46. PubMed ID: 25191940
[TBL] [Abstract][Full Text] [Related]
7. Developing novel classes of protein kinase CK1δ inhibitors by fusing [1,2,4]triazole with different bicyclic heteroaromatic systems.
Grieco I; Bissaro M; Tiz DB; Perez DI; Perez C; Martinez A; Redenti S; Mariotto E; Bortolozzi R; Viola G; Cozza G; Spalluto G; Moro S; Federico S
Eur J Med Chem; 2021 Apr; 216():113331. PubMed ID: 33721670
[TBL] [Abstract][Full Text] [Related]
8. Inhibition of gamma-secretase by the CK1 inhibitor IC261 does not depend on CK1delta.
Höttecke N; Liebeck M; Baumann K; Schubenel R; Winkler E; Steiner H; Schmidt B
Bioorg Med Chem Lett; 2010 May; 20(9):2958-63. PubMed ID: 20350806
[TBL] [Abstract][Full Text] [Related]
9. Structural basis for the interaction between casein kinase 1 delta and a potent and selective inhibitor.
Long A; Zhao H; Huang X
J Med Chem; 2012 Jan; 55(2):956-60. PubMed ID: 22168824
[TBL] [Abstract][Full Text] [Related]
10. Exploring isoxazoles and pyrrolidinones decorated with the 4,6-dimethoxy-1,3,5-triazine unit as human farnesyltransferase inhibitors.
Lucescu L; Ghinet A; Shova S; Magnez R; Thuru X; Farce A; Rigo B; Belei D; Dubois J; Bîcu E
Arch Pharm (Weinheim); 2019 May; 352(5):e1800227. PubMed ID: 30947375
[TBL] [Abstract][Full Text] [Related]
11. Synthesis of novel pyrrolidine 3,4-diol derivatives as inhibitors of alpha-L-fucosidases.
Moreno-Clavijo E; Carmona AT; Vera-Ayoso Y; Moreno-Vargas AJ; Bello C; Vogel P; Robina I
Org Biomol Chem; 2009 Mar; 7(6):1192-202. PubMed ID: 19262940
[TBL] [Abstract][Full Text] [Related]
12. The discovery of novel, potent and highly selective inhibitors of inducible nitric oxide synthase (iNOS).
Cheshire DR; Åberg A; Andersson GM; Andrews G; Beaton HG; Birkinshaw TN; Boughton-Smith N; Connolly S; Cook TR; Cooper A; Cooper SL; Cox D; Dixon J; Gensmantel N; Hamley PJ; Harrison R; Hartopp P; Käck H; Leeson PD; Luker T; Mete A; Millichip I; Nicholls DJ; Pimm AD; St-Gallay SA; Wallace AV
Bioorg Med Chem Lett; 2011 Apr; 21(8):2468-71. PubMed ID: 21398123
[TBL] [Abstract][Full Text] [Related]
13. 2-Benzamido-N-(1H-benzo[d]imidazol-2-yl)thiazole-4-carboxamide derivatives as potent inhibitors of CK1δ/ε.
Bischof J; Leban J; Zaja M; Grothey A; Radunsky B; Othersen O; Strobl S; Vitt D; Knippschild U
Amino Acids; 2012 Oct; 43(4):1577-91. PubMed ID: 22331384
[TBL] [Abstract][Full Text] [Related]
14. Structure-Based Development of Isoform-Selective Inhibitors of Casein Kinase 1ε vs Casein Kinase 1δ.
Choi JY; Noguchi Y; Alburger JM; Bayle S; Chung E; Grant W; Chaikuad A; Knapp S; Duckett DR; Roush WR
J Med Chem; 2023 Jun; 66(11):7162-7178. PubMed ID: 37204207
[TBL] [Abstract][Full Text] [Related]
15. Targeting the open-flap conformation of HIV-1 protease with pyrrolidine-based inhibitors.
Böttcher J; Blum A; Dörr S; Heine A; Diederich WE; Klebe G
ChemMedChem; 2008 Sep; 3(9):1337-44. PubMed ID: 18720485
[TBL] [Abstract][Full Text] [Related]
16. Design, synthesis and biological evaluation of potent FAAH inhibitors.
Tuo W; Leleu-Chavain N; Barczyk A; Renault N; Lemaire L; Chavatte P; Millet R
Bioorg Med Chem Lett; 2016 Jun; 26(11):2701-5. PubMed ID: 27117424
[TBL] [Abstract][Full Text] [Related]
17. Chiral iminoesters derived from D-glyceraldehyde in [3 + 2] cycloaddition reactions. Asymmetric synthesis of a key intermediate in the synthesis of neuramidinase inhibitors.
Gálvez JA; Díaz-de-Villegas MD; Alías M; Badorrey R
J Org Chem; 2013 Nov; 78(22):11404-13. PubMed ID: 24143968
[TBL] [Abstract][Full Text] [Related]
18. Dihydrobenzisoxazole-4-one compounds are novel selective inhibitors of aldosterone synthase (CYP11B2) with in vivo activity.
Meyers K; Cogan DA; Burke J; Arenas R; Balestra M; Brown NF; Chen Z; Cerny MA; Clifford HE; Colombo F; Fader L; Frederick KS; Guo X; Goldberg D; Hornberger KR; Kugler S; Lord J; Marshall DR; Moss N; Parmentier JH; Richman JR; Schmenk J; Weldon SM; Yu M; Zhang M
Bioorg Med Chem Lett; 2018 Mar; 28(5):979-984. PubMed ID: 29254646
[TBL] [Abstract][Full Text] [Related]
19. 2-Azo-, 2-diazocine-thiazols and 2-azo-imidazoles as photoswitchable kinase inhibitors: limitations and pitfalls of the photoswitchable inhibitor approach.
Schehr M; Ianes C; Weisner J; Heintze L; Müller MP; Pichlo C; Charl J; Brunstein E; Ewert J; Lehr M; Baumann U; Rauh D; Knippschild U; Peifer C; Herges R
Photochem Photobiol Sci; 2019 Jun; 18(6):1398-1407. PubMed ID: 30924488
[TBL] [Abstract][Full Text] [Related]
20. Regioselective synthesis of 3,4-diaryl-5-unsubstituted isoxazoles, analogues of natural cytostatic combretastatin A4.
Chernysheva NB; Maksimenko AS; Andreyanov FA; Kislyi VP; Strelenko YA; Khrustalev VN; Semenova MN; Semenov VV
Eur J Med Chem; 2018 Feb; 146():511-518. PubMed ID: 29407976
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
