BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

207 related articles for article (PubMed ID: 30832444)

  • 1. Thymoquinone Selectively Kills Hypoxic Renal Cancer Cells by Suppressing HIF-1α-Mediated Glycolysis.
    Lee YM; Kim GH; Park EJ; Oh TI; Lee S; Kan SY; Kang H; Kim BM; Kim JH; Lim JH
    Int J Mol Sci; 2019 Mar; 20(5):. PubMed ID: 30832444
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Hypoxia-inducible transcription factor-1alpha promotes hypoxia-induced A549 apoptosis via a mechanism that involves the glycolysis pathway.
    Luo F; Liu X; Yan N; Li S; Cao G; Cheng Q; Xia Q; Wang H
    BMC Cancer; 2006 Jan; 6():26. PubMed ID: 16438736
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Functional regulation of hypoxia inducible factor-1α by SET9 lysine methyltransferase.
    Liu Q; Geng H; Xue C; Beer TM; Qian DZ
    Biochim Biophys Acta; 2015 May; 1853(5):881-91. PubMed ID: 25637186
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Impairment of HIF-1α-mediated metabolic adaption by NRF2-silencing in breast cancer cells.
    Lee S; Hallis SP; Jung KA; Ryu D; Kwak MK
    Redox Biol; 2019 Jun; 24():101210. PubMed ID: 31078780
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Metabolic targeting of HIF-dependent glycolysis reduces lactate, increases oxygen consumption and enhances response to high-dose single-fraction radiotherapy in hypoxic solid tumors.
    Leung E; Cairns RA; Chaudary N; Vellanki RN; Kalliomaki T; Moriyama EH; Mujcic H; Wilson BC; Wouters BG; Hill R; Milosevic M
    BMC Cancer; 2017 Jun; 17(1):418. PubMed ID: 28619042
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Docetaxel induced-JNK2/PHD1 signaling pathway increases degradation of HIF-1α and causes cancer cell death under hypoxia.
    Oh ET; Kim CW; Kim SJ; Lee JS; Hong SS; Park HJ
    Sci Rep; 2016 Jun; 6():27382. PubMed ID: 27263528
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Effects of YC-1 on hypoxia-inducible factor 1 alpha in hypoxic human bladder transitional carcinoma cell line T24 cells.
    Li Y; Zhao X; Tang H; Zhong Z; Zhang L; Xu R; Li S; Wang Y
    Urol Int; 2012; 88(1):95-101. PubMed ID: 22041818
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Thymoquinone has a synergistic effect with PHD inhibitors to ameliorate ischemic brain damage in mice.
    Amin N; Chen S; Ye S; Wu F; Hussien AB; Lou C; Hu Z; Wang Y; Wu J; Fang M
    Phytomedicine; 2022 Sep; 104():154298. PubMed ID: 35797865
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Targeting aerobic glycolysis and HIF-1alpha expression enhance imiquimod-induced apoptosis in cancer cells.
    Huang SW; Kao JK; Wu CY; Wang ST; Lee HC; Liang SM; Chen YJ; Shieh JJ
    Oncotarget; 2014 Mar; 5(5):1363-81. PubMed ID: 24658058
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Wortmannin influences hypoxia-inducible factor-1 alpha expression and glycolysis in esophageal carcinoma cells.
    Zeng L; Zhou HY; Tang NN; Zhang WF; He GJ; Hao B; Feng YD; Zhu H
    World J Gastroenterol; 2016 May; 22(20):4868-80. PubMed ID: 27239113
    [TBL] [Abstract][Full Text] [Related]  

  • 11. A group of novel HIF-1α inhibitors, glyceollins, blocks HIF-1α synthesis and decreases its stability via inhibition of the PI3K/AKT/mTOR pathway and Hsp90 binding.
    Lee SH; Jee JG; Bae JS; Liu KH; Lee YM
    J Cell Physiol; 2015 Apr; 230(4):853-62. PubMed ID: 25204544
    [TBL] [Abstract][Full Text] [Related]  

  • 12. The novel hypoxia-inducible factor-1α inhibitor IDF-11774 regulates cancer metabolism, thereby suppressing tumor growth.
    Ban HS; Kim BK; Lee H; Kim HM; Harmalkar D; Nam M; Park SK; Lee K; Park JT; Kim I; Lee K; Hwang GS; Won M
    Cell Death Dis; 2017 Jun; 8(6):e2843. PubMed ID: 28569777
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Chlorogenic acid inhibits hypoxia-induced angiogenesis via down-regulation of the HIF-1α/AKT pathway.
    Park JJ; Hwang SJ; Park JH; Lee HJ
    Cell Oncol (Dordr); 2015 Apr; 38(2):111-8. PubMed ID: 25561311
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Albendazole inhibits HIF-1α-dependent glycolysis and VEGF expression in non-small cell lung cancer cells.
    Zhou F; Du J; Wang J
    Mol Cell Biochem; 2017 Apr; 428(1-2):171-178. PubMed ID: 28063005
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Magnolol suppresses hypoxia-induced angiogenesis via inhibition of HIF-1α/VEGF signaling pathway in human bladder cancer cells.
    Chen MC; Lee CF; Huang WH; Chou TC
    Biochem Pharmacol; 2013 May; 85(9):1278-87. PubMed ID: 23416116
    [TBL] [Abstract][Full Text] [Related]  

  • 16. An Akt/hypoxia-inducible factor-1alpha/platelet-derived growth factor-BB autocrine loop mediates hypoxia-induced chemoresistance in liver cancer cells and tumorigenic hepatic progenitor cells.
    Lau CK; Yang ZF; Ho DW; Ng MN; Yeoh GC; Poon RT; Fan ST
    Clin Cancer Res; 2009 May; 15(10):3462-71. PubMed ID: 19447872
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Ion channel TRPM8 promotes hypoxic growth of prostate cancer cells via an O2 -independent and RACK1-mediated mechanism of HIF-1α stabilization.
    Yu S; Xu Z; Zou C; Wu D; Wang Y; Yao X; Ng CF; Chan FL
    J Pathol; 2014 Dec; 234(4):514-25. PubMed ID: 25065497
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Molecular and functional evaluation of a novel HIF inhibitor, benzopyranyl 1,2,3-triazole compound.
    Park K; Lee HE; Lee SH; Lee D; Lee T; Lee YM
    Oncotarget; 2017 Jan; 8(5):7801-7813. PubMed ID: 27999195
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Effects of geldanamycin on HIF-1alpha mediated angiogenesis and invasion in prostate cancer cells.
    Alqawi O; Moghaddas M; Singh G
    Prostate Cancer Prostatic Dis; 2006; 9(2):126-35. PubMed ID: 16432534
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Cyclin-dependent kinase inhibitor, P276-00, inhibits HIF-1α and induces G2/M arrest under hypoxia in prostate cancer cells.
    Manohar SM; Padgaonkar AA; Jalota-Badhwar A; Rao SV; Joshi KS
    Prostate Cancer Prostatic Dis; 2012 Mar; 15(1):15-27. PubMed ID: 22083267
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.