These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
2. Differential kinase activity of ACVR1 G328V and R206H mutations with implications to possible TβRI cross-talk in diffuse intrinsic pontine glioma. Cao H; Jin M; Gao M; Zhou H; Tao YJ; Skolnick J Sci Rep; 2020 Apr; 10(1):6140. PubMed ID: 32273545 [TBL] [Abstract][Full Text] [Related]
3. Mutant ACVR1 Arrests Glial Cell Differentiation to Drive Tumorigenesis in Pediatric Gliomas. Fortin J; Tian R; Zarrabi I; Hill G; Williams E; Sanchez-Duffhues G; Thorikay M; Ramachandran P; Siddaway R; Wong JF; Wu A; Apuzzo LN; Haight J; You-Ten A; Snow BE; Wakeham A; Goldhamer DJ; Schramek D; Bullock AN; Dijke PT; Hawkins C; Mak TW Cancer Cell; 2020 Mar; 37(3):308-323.e12. PubMed ID: 32142668 [TBL] [Abstract][Full Text] [Related]
4. ALK2 inhibitors display beneficial effects in preclinical models of Carvalho D; Taylor KR; Olaciregui NG; Molinari V; Clarke M; Mackay A; Ruddle R; Henley A; Valenti M; Hayes A; Brandon AH; Eccles SA; Raynaud F; Boudhar A; Monje M; Popov S; Moore AS; Mora J; Cruz O; Vinci M; Brennan PE; Bullock AN; Carcaboso AM; Jones C Commun Biol; 2019; 2():156. PubMed ID: 31098401 [TBL] [Abstract][Full Text] [Related]
5. Genomic analysis of diffuse intrinsic pontine gliomas identifies three molecular subgroups and recurrent activating ACVR1 mutations. Buczkowicz P; Hoeman C; Rakopoulos P; Pajovic S; Letourneau L; Dzamba M; Morrison A; Lewis P; Bouffet E; Bartels U; Zuccaro J; Agnihotri S; Ryall S; Barszczyk M; Chornenkyy Y; Bourgey M; Bourque G; Montpetit A; Cordero F; Castelo-Branco P; Mangerel J; Tabori U; Ho KC; Huang A; Taylor KR; Mackay A; Bendel AE; Nazarian J; Fangusaro JR; Karajannis MA; Zagzag D; Foreman NK; Donson A; Hegert JV; Smith A; Chan J; Lafay-Cousin L; Dunn S; Hukin J; Dunham C; Scheinemann K; Michaud J; Zelcer S; Ramsay D; Cain J; Brennan C; Souweidane MM; Jones C; Allis CD; Brudno M; Becher O; Hawkins C Nat Genet; 2014 May; 46(5):451-6. PubMed ID: 24705254 [TBL] [Abstract][Full Text] [Related]
6. Potent anti-tumor efficacy of palbociclib in treatment-naïve H3.3K27M-mutant diffuse intrinsic pontine glioma. Sun Y; Sun Y; Yan K; Li Z; Xu C; Geng Y; Pan C; Chen X; Zhang L; Xi Q EBioMedicine; 2019 May; 43():171-179. PubMed ID: 31060906 [TBL] [Abstract][Full Text] [Related]
7. Spatial and temporal homogeneity of driver mutations in diffuse intrinsic pontine glioma. Nikbakht H; Panditharatna E; Mikael LG; Li R; Gayden T; Osmond M; Ho CY; Kambhampati M; Hwang EI; Faury D; Siu A; Papillon-Cavanagh S; Bechet D; Ligon KL; Ellezam B; Ingram WJ; Stinson C; Moore AS; Warren KE; Karamchandani J; Packer RJ; Jabado N; Majewski J; Nazarian J Nat Commun; 2016 Apr; 7():11185. PubMed ID: 27048880 [TBL] [Abstract][Full Text] [Related]
11. Repurposing Vandetanib plus Everolimus for the Treatment of Carvalho DM; Richardson PJ; Olaciregui N; Stankunaite R; Lavarino C; Molinari V; Corley EA; Smith DP; Ruddle R; Donovan A; Pal A; Raynaud FI; Temelso S; Mackay A; Overington JP; Phelan A; Sheppard D; Mackinnon A; Zebian B; Al-Sarraj S; Merve A; Pryce J; Grill J; Hubank M; Cruz O; Morales La Madrid A; Mueller S; Carcaboso AM; Carceller F; Jones C Cancer Discov; 2022 Feb; 12(2):416-431. PubMed ID: 34551970 [TBL] [Abstract][Full Text] [Related]
12. Histone H3K27 methylation modulates the dynamics of FANCD2 on chromatin to facilitate NHEJ and genome stability. Zhang Y; Chang JF; Sun J; Chen L; Yang XM; Tang HY; Jing YY; Kang X; He ZM; Wu JY; Wei HM; Wang DL; Xu RG; Zhu RB; Shen Y; Zeng SY; Wang C; Liu KN; Zhang Y; Mao ZY; Jiang CZ; Sun FL J Cell Sci; 2018 Jun; 131(12):. PubMed ID: 29760279 [TBL] [Abstract][Full Text] [Related]
13. Transcriptional Dependencies in Diffuse Intrinsic Pontine Glioma. Nagaraja S; Vitanza NA; Woo PJ; Taylor KR; Liu F; Zhang L; Li M; Meng W; Ponnuswami A; Sun W; Ma J; Hulleman E; Swigut T; Wysocka J; Tang Y; Monje M Cancer Cell; 2017 May; 31(5):635-652.e6. PubMed ID: 28434841 [TBL] [Abstract][Full Text] [Related]
14. Recurrent activating ACVR1 mutations in diffuse intrinsic pontine glioma. Taylor KR; Mackay A; Truffaux N; Butterfield Y; Morozova O; Philippe C; Castel D; Grasso CS; Vinci M; Carvalho D; Carcaboso AM; de Torres C; Cruz O; Mora J; Entz-Werle N; Ingram WJ; Monje M; Hargrave D; Bullock AN; Puget S; Yip S; Jones C; Grill J Nat Genet; 2014 May; 46(5):457-461. PubMed ID: 24705252 [TBL] [Abstract][Full Text] [Related]
15. Pathogenic ACVR1 Ramachandran A; Mehić M; Wasim L; Malinova D; Gori I; Blaszczyk BK; Carvalho DM; Shore EM; Jones C; Hyvönen M; Tolar P; Hill CS EMBO J; 2021 Jul; 40(14):e106317. PubMed ID: 34003511 [TBL] [Abstract][Full Text] [Related]
16. A pontine-specific axonal niche supports de novo gliomagenesis. Xie Z; Pathak A; Bankaitis VA bioRxiv; 2024 Sep; ():. PubMed ID: 39282464 [TBL] [Abstract][Full Text] [Related]
17. A Novel Mouse Model of Diffuse Intrinsic Pontine Glioma Initiated in Pax3-Expressing Cells. Misuraca KL; Hu G; Barton KL; Chung A; Becher OJ Neoplasia; 2016 Jan; 18(1):60-70. PubMed ID: 26806352 [TBL] [Abstract][Full Text] [Related]
18. BMP2 and BMP7 cooperate with H3.3K27M to promote quiescence and invasiveness in pediatric diffuse midline gliomas. Huchede P; Meyer S; Berthelot C; Hamadou M; Bertrand-Chapel A; Rakotomalala A; Manceau L; Tomine J; Lespinasse N; Lewandowski P; Cordier-Bussat M; Broutier L; Dutour A; Rochet I; Blay JY; Degletagne C; Attignon V; Montero-Carcaboso A; Le Grand M; Pasquier E; Vasiljevic A; Gilardi-Hebenstreit P; Meignan S; Leblond P; Ribes V; Cosset E; Castets M Elife; 2024 Oct; 12():. PubMed ID: 39373720 [TBL] [Abstract][Full Text] [Related]
19. Shared ACVR1 mutations in FOP and DIPG: Opportunities and challenges in extending biological and clinical implications across rare diseases. Han HJ; Jain P; Resnick AC Bone; 2018 Apr; 109():91-100. PubMed ID: 28780023 [TBL] [Abstract][Full Text] [Related]