These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

220 related articles for article (PubMed ID: 30833575)

  • 1. Pocket similarity identifies selective estrogen receptor modulators as microtubule modulators at the taxane site.
    Lo YC; Cormier O; Liu T; Nettles KW; Katzenellenbogen JA; Stearns T; Altman RB
    Nat Commun; 2019 Mar; 10(1):1033. PubMed ID: 30833575
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Molecular mechanism of action of microtubule-stabilizing anticancer agents.
    Prota AE; Bargsten K; Zurwerra D; Field JJ; Díaz JF; Altmann KH; Steinmetz MO
    Science; 2013 Feb; 339(6119):587-90. PubMed ID: 23287720
    [TBL] [Abstract][Full Text] [Related]  

  • 3. The cytotoxic natural compound erianin binds to colchicine site of β-tubulin and overcomes taxane resistance.
    Yan W; Zhou Y; Yuan X; Bai P; Tang M; Chen L; Wei H; Yang J
    Bioorg Chem; 2024 Sep; 150():107569. PubMed ID: 38905886
    [TBL] [Abstract][Full Text] [Related]  

  • 4. A semisynthetic taxane Yg-3-46a effectively evades P-glycoprotein and β-III tubulin mediated tumor drug resistance in vitro.
    Cai P; Lu P; Sharom FJ; Fang WS
    Cancer Lett; 2013 Dec; 341(2):214-23. PubMed ID: 23941826
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Structural Basis of Microtubule Stabilization by Discodermolide.
    Prota AE; Bargsten K; Redondo-Horcajo M; Smith AB; Yang CH; McDaid HM; Paterson I; Horwitz SB; Fernando Díaz J; Steinmetz MO
    Chembiochem; 2017 May; 18(10):905-909. PubMed ID: 28207984
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Taxanes with high potency inducing tubulin assembly overcome tumoural cell resistances.
    Matesanz R; Trigili C; Rodríguez-Salarichs J; Zanardi I; Pera B; Nogales A; Fang WS; Jímenez-Barbero J; Canales A; Barasoain I; Ojima I; Díaz JF
    Bioorg Med Chem; 2014 Sep; 22(18):5078-90. PubMed ID: 25047938
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Relationship between the structures of taxane derivatives and their microtubule polymerization activity.
    Hidaka M; Koga T; Kiyota H; Horiguchi T; Shi QW; Hirose K; Uchida T
    Biosci Biotechnol Biochem; 2012; 76(2):349-52. PubMed ID: 22313785
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Preclinical pharmacologic evaluation of MST-997, an orally active taxane with superior in vitro and in vivo efficacy in paclitaxel- and docetaxel-resistant tumor models.
    Sampath D; Greenberger LM; Beyer C; Hari M; Liu H; Baxter M; Yang S; Rios C; Discafani C
    Clin Cancer Res; 2006 Jun; 12(11 Pt 1):3459-69. PubMed ID: 16740771
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Differences in paclitaxel and docetaxel interactions with tubulin detected by mutagenesis of yeast tubulin.
    Winefield RD; Entwistle RA; Foland TB; Lushington GH; Himes RH
    ChemMedChem; 2008 Dec; 3(12):1844-7. PubMed ID: 18988212
    [No Abstract]   [Full Text] [Related]  

  • 10. Zampanolide, a potent new microtubule-stabilizing agent, covalently reacts with the taxane luminal site in tubulin α,β-heterodimers and microtubules.
    Field JJ; Pera B; Calvo E; Canales A; Zurwerra D; Trigili C; Rodríguez-Salarichs J; Matesanz R; Kanakkanthara A; Wakefield SJ; Singh AJ; Jiménez-Barbero J; Northcote P; Miller JH; López JA; Hamel E; Barasoain I; Altmann KH; Díaz JF
    Chem Biol; 2012 Jun; 19(6):686-98. PubMed ID: 22726683
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Insights into the interaction of discodermolide and docetaxel with tubulin. Mapping the binding sites of microtubule-stabilizing agents by using an integrated NMR and computational approach.
    Canales A; Rodríguez-Salarichs J; Trigili C; Nieto L; Coderch C; Andreu JM; Paterson I; Jiménez-Barbero J; Díaz JF
    ACS Chem Biol; 2011 Aug; 6(8):789-99. PubMed ID: 21539341
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Understanding tubulin/microtubule-taxane interactions: a quantitative structure-activity relationship study.
    Hansch C; Verma RP
    Mol Pharm; 2008; 5(1):151-61. PubMed ID: 18171015
    [TBL] [Abstract][Full Text] [Related]  

  • 13. CoMFA, HQSAR and molecular docking studies of butitaxel analogues with beta-tubulin.
    Cunningham SL; Cunningham AR; Day BW
    J Mol Model; 2005 Feb; 11(1):48-54. PubMed ID: 15616834
    [TBL] [Abstract][Full Text] [Related]  

  • 14. A Potent, Metabolically Stable Tubulin Inhibitor Targets the Colchicine Binding Site and Overcomes Taxane Resistance.
    Arnst KE; Wang Y; Hwang DJ; Xue Y; Costello T; Hamilton D; Chen Q; Yang J; Park F; Dalton JT; Miller DD; Li W
    Cancer Res; 2018 Jan; 78(1):265-277. PubMed ID: 29180476
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Novel taxane derivatives from Taxus wallichiana with high anticancer potency on tumor cells.
    Wang Y; Wang J; Wang H; Ye W
    Chem Biol Drug Des; 2016 Oct; 88(4):556-61. PubMed ID: 27153813
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Microtubule Destabilizing Sulfonamides as an Alternative to Taxane-Based Chemotherapy.
    González M; Ovejero-Sánchez M; Vicente-Blázquez A; Álvarez R; Herrero AB; Medarde M; González-Sarmiento R; Peláez R
    Int J Mol Sci; 2021 Feb; 22(4):. PubMed ID: 33673002
    [TBL] [Abstract][Full Text] [Related]  

  • 17. The seco-taxane IDN5390 is able to target class III beta-tubulin and to overcome paclitaxel resistance.
    Ferlini C; Raspaglio G; Mozzetti S; Cicchillitti L; Filippetti F; Gallo D; Fattorusso C; Campiani G; Scambia G
    Cancer Res; 2005 Mar; 65(6):2397-405. PubMed ID: 15781655
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Efficacy of a Covalent Microtubule Stabilizer in Taxane-Resistant Ovarian Cancer Models.
    Yee SS; Risinger AL
    Molecules; 2021 Jul; 26(13):. PubMed ID: 34279417
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Cyclostreptin binds covalently to microtubule pores and lumenal taxoid binding sites.
    Buey RM; Calvo E; Barasoain I; Pineda O; Edler MC; Matesanz R; Cerezo G; Vanderwal CD; Day BW; Sorensen EJ; López JA; Andreu JM; Hamel E; Díaz JF
    Nat Chem Biol; 2007 Feb; 3(2):117-25. PubMed ID: 17206139
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Zampanolide and dactylolide: cytotoxic tubulin-assembly agents and promising anticancer leads.
    Chen QH; Kingston DG
    Nat Prod Rep; 2014 Sep; 31(9):1202-26. PubMed ID: 24945566
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.