BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

119 related articles for article (PubMed ID: 30835473)

  • 1. Novel Triapine Derivative Induces Copper-Dependent Cell Death in Hematopoietic Cancers.
    Chen G; Niu C; Yi J; Sun L; Cao H; Fang Y; Jin T; Li Y; Lou C; Kang J; Wei W; Zhu J
    J Med Chem; 2019 Mar; 62(6):3107-3121. PubMed ID: 30835473
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Ribonucleotide reductase inhibition by metal complexes of Triapine (3-aminopyridine-2-carboxaldehyde thiosemicarbazone): a combined experimental and theoretical study.
    Popović-Bijelić A; Kowol CR; Lind ME; Luo J; Himo F; Enyedy EA; Arion VB; Gräslund A
    J Inorg Biochem; 2011 Nov; 105(11):1422-31. PubMed ID: 21955844
    [TBL] [Abstract][Full Text] [Related]  

  • 3. The thiosemicarbazone Me
    Hager S; Korbula K; Bielec B; Grusch M; Pirker C; Schosserer M; Liendl L; Lang M; Grillari J; Nowikovsky K; Pape VFS; Mohr T; Szakács G; Keppler BK; Berger W; Kowol CR; Heffeter P
    Cell Death Dis; 2018 Oct; 9(11):1052. PubMed ID: 30323190
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Impact of Stepwise NH2-Methylation of Triapine on the Physicochemical Properties, Anticancer Activity, and Resistance Circumvention.
    Kowol CR; Miklos W; Pfaff S; Hager S; Kallus S; Pelivan K; Kubanik M; Enyedy ÉA; Berger W; Heffeter P; Keppler BK
    J Med Chem; 2016 Jul; 59(14):6739-52. PubMed ID: 27336684
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Distinct mechanisms of cell-kill by triapine and its terminally dimethylated derivative Dp44mT due to a loss or gain of activity of their copper(II) complexes.
    Ishiguro K; Lin ZP; Penketh PG; Shyam K; Zhu R; Baumann RP; Zhu YL; Sartorelli AC; Rutherford TJ; Ratner ES
    Biochem Pharmacol; 2014 Oct; 91(3):312-22. PubMed ID: 25130544
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Differences in protein binding and excretion of Triapine and its Fe(III) complex.
    Pelivan K; Miklos W; van Schoonhoven S; Koellensperger G; Gille L; Berger W; Heffeter P; Kowol CR; Keppler BK
    J Inorg Biochem; 2016 Jul; 160():61-9. PubMed ID: 26507768
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Triapine (3-aminopyridine-2-carboxaldehyde- thiosemicarbazone): A potent inhibitor of ribonucleotide reductase activity with broad spectrum antitumor activity.
    Finch RA; Liu M; Grill SP; Rose WC; Loomis R; Vasquez KM; Cheng Y; Sartorelli AC
    Biochem Pharmacol; 2000 Apr; 59(8):983-91. PubMed ID: 10692563
    [TBL] [Abstract][Full Text] [Related]  

  • 8. A Ferrous-Triapine complex mediates formation of reactive oxygen species that inactivate human ribonucleotide reductase.
    Shao J; Zhou B; Di Bilio AJ; Zhu L; Wang T; Qi C; Shih J; Yen Y
    Mol Cancer Ther; 2006 Mar; 5(3):586-92. PubMed ID: 16546972
    [TBL] [Abstract][Full Text] [Related]  

  • 9. P38 MAP kinase functions as a switch in MS-275-induced reactive oxygen species-dependent autophagy and apoptosis in human colon cancer cells.
    Zhan Y; Gong K; Chen C; Wang H; Li W
    Free Radic Biol Med; 2012 Aug; 53(3):532-43. PubMed ID: 22634147
    [TBL] [Abstract][Full Text] [Related]  

  • 10. p38MAPK-Dependent sensitivity of Ewing's sarcoma family of tumors to fenretinide-induced cell death.
    Myatt SS; Redfern CP; Burchill SA
    Clin Cancer Res; 2005 Apr; 11(8):3136-48. PubMed ID: 15837770
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Enhanced targeting of mitochondrial peroxide defense by the combined use of thiosemicarbazones and inhibitors of thioredoxin reductase.
    Myers CR
    Free Radic Biol Med; 2016 Feb; 91():81-92. PubMed ID: 26686468
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Triapine and a more potent dimethyl derivative induce endoplasmic reticulum stress in cancer cells.
    Trondl R; Flocke LS; Kowol CR; Heffeter P; Jungwirth U; Mair GE; Steinborn R; Enyedy ÉA; Jakupec MA; Berger W; Keppler BK
    Mol Pharmacol; 2014 Mar; 85(3):451-9. PubMed ID: 24378333
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Examination of the antiproliferative activity of iron chelators: multiple cellular targets and the different mechanism of action of triapine compared with desferrioxamine and the potent pyridoxal isonicotinoyl hydrazone analogue 311.
    Chaston TB; Lovejoy DB; Watts RN; Richardson DR
    Clin Cancer Res; 2003 Jan; 9(1):402-14. PubMed ID: 12538494
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Triapine (3-aminopyridine-2-carboxaldehyde thiosemicarbazone) induces apoptosis in ovarian cancer cells.
    Alvero AB; Chen W; Sartorelli AC; Schwartz P; Rutherford T; Mor G
    J Soc Gynecol Investig; 2006 Feb; 13(2):145-52. PubMed ID: 16443509
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Tumor growth inhibition by arsenic trioxide (As2O3) in the orthotopic metastasis model of androgen-independent prostate cancer.
    Maeda H; Hori S; Nishitoh H; Ichijo H; Ogawa O; Kakehi Y; Kakizuka A
    Cancer Res; 2001 Jul; 61(14):5432-40. PubMed ID: 11454688
    [TBL] [Abstract][Full Text] [Related]  

  • 16. A novel synthetic analog of Militarin, MA-1 induces mitochondrial dependent apoptosis by ROS generation in human lung cancer cells.
    Yoon DH; Lim MH; Lee YR; Sung GH; Lee TH; Jeon BH; Cho JY; Song WO; Park H; Choi S; Kim TW
    Toxicol Appl Pharmacol; 2013 Dec; 273(3):659-71. PubMed ID: 24161344
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Liposomal formulations of anticancer copper(II) thiosemicarbazone complexes.
    Mathuber M; Hager S; Keppler BK; Heffeter P; Kowol CR
    Dalton Trans; 2021 Nov; 50(44):16053-16066. PubMed ID: 34617075
    [TBL] [Abstract][Full Text] [Related]  

  • 18. CR108, a novel vitamin K3 derivative induces apoptosis and breast tumor inhibition by reactive oxygen species and mitochondrial dysfunction.
    Yang CR; Liao WS; Wu YH; Murugan K; Chen C; Chao JI
    Toxicol Appl Pharmacol; 2013 Dec; 273(3):611-22. PubMed ID: 24128853
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Combination of triapine, olaparib, and cediranib suppresses progression of BRCA-wild type and PARP inhibitor-resistant epithelial ovarian cancer.
    Lin ZP; Zhu YL; Lo YC; Moscarelli J; Xiong A; Korayem Y; Huang PH; Giri S; LoRusso P; Ratner ES
    PLoS One; 2018; 13(11):e0207399. PubMed ID: 30444904
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Apoptosis induced by a new flavonoid in human hepatoma HepG2 cells involves reactive oxygen species-mediated mitochondrial dysfunction and MAPK activation.
    Liu H; Xiao Y; Xiong C; Wei A; Ruan J
    Eur J Pharmacol; 2011 Mar; 654(3):209-16. PubMed ID: 21241688
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 6.