BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

195 related articles for article (PubMed ID: 30836057)

  • 1. Novel benzoxanthene lignans that favorably modulate lipid mediator biosynthesis: A promising pharmacological strategy for anti-inflammatory therapy.
    Gerstmeier J; Kretzer C; Di Micco S; Miek L; Butschek H; Cantone V; Bilancia R; Rizza R; Troisi F; Cardullo N; Tringali C; Ialenti A; Rossi A; Bifulco G; Werz O; Pace S
    Biochem Pharmacol; 2019 Jul; 165():263-274. PubMed ID: 30836057
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Discovery of a benzenesulfonamide-based dual inhibitor of microsomal prostaglandin E
    Cheung SY; Werner M; Esposito L; Troisi F; Cantone V; Liening S; König S; Gerstmeier J; Koeberle A; Bilancia R; Rizza R; Rossi A; Roviezzo F; Temml V; Schuster D; Stuppner H; Schubert-Zsilavecz M; Werz O; Hanke T; Pace S
    Eur J Med Chem; 2018 Aug; 156():815-830. PubMed ID: 30053720
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Anti-inflammatory celastrol promotes a switch from leukotriene biosynthesis to formation of specialized pro-resolving lipid mediators.
    Pace S; Zhang K; Jordan PM; Bilancia R; Wang W; Börner F; Hofstetter RK; Potenza M; Kretzer C; Gerstmeier J; Fischer D; Lorkowski S; Gilbert NC; Newcomer ME; Rossi A; Chen X; Werz O
    Pharmacol Res; 2021 May; 167():105556. PubMed ID: 33812006
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Natural chalcones elicit formation of specialized pro-resolving mediators and related 15-lipoxygenase products in human macrophages.
    Kretzer C; Jordan PM; Meyer KPL; Hoff D; Werner M; Hofstetter RK; Koeberle A; Cala Peralta A; Viault G; Seraphin D; Richomme P; Helesbeux JJ; Stuppner H; Temml V; Schuster D; Werz O
    Biochem Pharmacol; 2022 Jan; 195():114825. PubMed ID: 34762841
    [TBL] [Abstract][Full Text] [Related]  

  • 5. The novel benzimidazole derivative BRP-7 inhibits leukotriene biosynthesis in vitro and in vivo by targeting 5-lipoxygenase-activating protein (FLAP).
    Pergola C; Gerstmeier J; Mönch B; Çalışkan B; Luderer S; Weinigel C; Barz D; Maczewsky J; Pace S; Rossi A; Sautebin L; Banoglu E; Werz O
    Br J Pharmacol; 2014 Jun; 171(12):3051-64. PubMed ID: 24641614
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Shifting the Biosynthesis of Leukotrienes Toward Specialized Pro-Resolving Mediators by the 5-Lipoxygenase-Activating Protein (FLAP) Antagonist BRP-201.
    Kretzer C; Jordan PM; Bilancia R; Rossi A; Gür Maz T; Banoglu E; Schubert US; Werz O
    J Inflamm Res; 2022; 15():911-925. PubMed ID: 35173459
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Targeting biosynthetic networks of the proinflammatory and proresolving lipid metabolome.
    Werner M; Jordan PM; Romp E; Czapka A; Rao Z; Kretzer C; Koeberle A; Garscha U; Pace S; Claesson HE; Serhan CN; Werz O; Gerstmeier J
    FASEB J; 2019 May; 33(5):6140-6153. PubMed ID: 30735438
    [TBL] [Abstract][Full Text] [Related]  

  • 8. From Vietnamese plants to a biflavonoid that relieves inflammation by triggering the lipid mediator class switch to resolution.
    Van Anh TT; Mostafa A; Rao Z; Pace S; Schwaiger S; Kretzer C; Temml V; Giesel C; Jordan PM; Bilancia R; Weinigel C; Rummler S; Waltenberger B; Hung T; Rossi A; Stuppner H; Werz O; Koeberle A
    Acta Pharm Sin B; 2021 Jun; 11(6):1629-1647. PubMed ID: 34221873
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Rotational constriction of curcuminoids impacts 5-lipoxygenase and mPGES-1 inhibition and evokes a lipid mediator class switch in macrophages.
    Rao Z; Caprioglio D; Gollowitzer A; Kretzer C; Imperio D; Collado JA; Waltl L; Lackner S; Appendino G; Muñoz E; Temml V; Werz O; Minassi A; Koeberle A
    Biochem Pharmacol; 2022 Sep; 203():115202. PubMed ID: 35932797
    [TBL] [Abstract][Full Text] [Related]  

  • 10. BRP-187: A potent inhibitor of leukotriene biosynthesis that acts through impeding the dynamic 5-lipoxygenase/5-lipoxygenase-activating protein (FLAP) complex assembly.
    Garscha U; Voelker S; Pace S; Gerstmeier J; Emini B; Liening S; Rossi A; Weinigel C; Rummler S; Schubert US; Scriba GK; Çelikoğlu E; Çalışkan B; Banoglu E; Sautebin L; Werz O
    Biochem Pharmacol; 2016 Nov; 119():17-26. PubMed ID: 27592027
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Beneficial Modulation of Lipid Mediator Biosynthesis in Innate Immune Cells by Antirheumatic
    Zhang K; Pace S; Jordan PM; Peltner LK; Weber A; Fischer D; Hofstetter RK; Chen X; Werz O
    Biomolecules; 2021 May; 11(5):. PubMed ID: 34067705
    [No Abstract]   [Full Text] [Related]  

  • 12. Ginkgolic Acid is a Multi-Target Inhibitor of Key Enzymes in Pro-Inflammatory Lipid Mediator Biosynthesis.
    Gerstmeier J; Seegers J; Witt F; Waltenberger B; Temml V; Rollinger JM; Stuppner H; Koeberle A; Schuster D; Werz O
    Front Pharmacol; 2019; 10():797. PubMed ID: 31379572
    [No Abstract]   [Full Text] [Related]  

  • 13. Natural products as inhibitors of prostaglandin E
    Koeberle A; Werz O
    Biotechnol Adv; 2018 Nov; 36(6):1709-1723. PubMed ID: 29454981
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Differential impact of 5-lipoxygenase-activating protein antagonists on the biosynthesis of leukotrienes and of specialized pro-resolving mediators.
    Dahlke P; Peltner LK; Jordan PM; Werz O
    Front Pharmacol; 2023; 14():1219160. PubMed ID: 37680719
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Untangling the web of 5-lipoxygenase-derived products from a molecular and structural perspective: The battle between pro- and anti-inflammatory lipid mediators.
    Gilbert NC; Newcomer ME; Werz O
    Biochem Pharmacol; 2021 Nov; 193():114759. PubMed ID: 34487716
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Identification of multi-target inhibitors of leukotriene and prostaglandin E
    Gür ZT; Çalışkan B; Garscha U; Olgaç A; Schubert US; Gerstmeier J; Werz O; Banoglu E
    Eur J Med Chem; 2018 Apr; 150():876-899. PubMed ID: 29597170
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Modulation of Inflammation-Related Lipid Mediator Pathways by Celastrol During Human Macrophage Polarization.
    Zhang K; Jordan PM; Pace S; Hofstetter RK; Werner M; Chen X; Werz O
    J Inflamm Res; 2022; 15():3285-3304. PubMed ID: 35676971
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Identification of selective 5-LOX and FLAP inhibitors as novel anti-inflammatory agents by ligand-based virtual screening.
    Cerchia C; Küfner L; Werz O; Lavecchia A
    Eur J Med Chem; 2024 Jan; 263():115932. PubMed ID: 37976708
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Cannabidiol acts as molecular switch in innate immune cells to promote the biosynthesis of inflammation-resolving lipid mediators.
    Peltner LK; Gluthmann L; Börner F; Pace S; Hoffstetter RK; Kretzer C; Bilancia R; Pollastro F; Koeberle A; Appendino G; Rossi A; Newcomer ME; Gilbert NC; Werz O; Jordan PM
    Cell Chem Biol; 2023 Dec; 30(12):1508-1524.e7. PubMed ID: 37647900
    [TBL] [Abstract][Full Text] [Related]  

  • 20. The 5-lipoxygenase inhibitor RF-22c potently suppresses leukotriene biosynthesis in cellulo and blocks bronchoconstriction and inflammation in vivo.
    Schaible AM; Filosa R; Krauth V; Temml V; Pace S; Garscha U; Liening S; Weinigel C; Rummler S; Schieferdecker S; Nett M; Peduto A; Collarile S; Scuotto M; Roviezzo F; Spaziano G; de Rosa M; Stuppner H; Schuster D; D'Agostino B; Werz O
    Biochem Pharmacol; 2016 Jul; 112():60-71. PubMed ID: 27157409
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.