These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

221 related articles for article (PubMed ID: 30837304)

  • 21. The multi-site docking protein Grb2-associated binder 1 (Gab1) enhances interleukin-6-induced MAPK-pathway activation in an SHP2-, Grb2-, and time-dependent manner.
    Bongartz H; Gille K; Hessenkemper W; Mandel K; Lewitzky M; Feller SM; Schaper F
    Cell Commun Signal; 2019 Oct; 17(1):135. PubMed ID: 31651330
    [TBL] [Abstract][Full Text] [Related]  

  • 22. The down-regulation of tyrosine phosphatase SHP2 activity is involved in the removal of surface AMPA receptors in long term depression.
    Zhou H; Xie Y; Fang W; Du Y; Zhou J; Du L; Zhang B
    Neurosci Lett; 2022 May; 779():136636. PubMed ID: 35439551
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Protein-tyrosine phosphatase Shp2 positively regulates macrophage oxidative burst.
    Li XJ; Goodwin CB; Nabinger SC; Richine BM; Yang Z; Hanenberg H; Ohnishi H; Matozaki T; Feng GS; Chan RJ
    J Biol Chem; 2015 Feb; 290(7):3894-909. PubMed ID: 25538234
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Noonan syndrome mutation Q79R in Shp2 increases proliferation of valve primordia mesenchymal cells via extracellular signal-regulated kinase 1/2 signaling.
    Krenz M; Yutzey KE; Robbins J
    Circ Res; 2005 Oct; 97(8):813-20. PubMed ID: 16166557
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Aberrant neuronal activity-induced signaling and gene expression in a mouse model of RASopathy.
    Altmüller F; Pothula S; Annamneedi A; Nakhaei-Rad S; Montenegro-Venegas C; Pina-Fernández E; Marini C; Santos M; Schanze D; Montag D; Ahmadian MR; Stork O; Zenker M; Fejtova A
    PLoS Genet; 2017 Mar; 13(3):e1006684. PubMed ID: 28346493
    [TBL] [Abstract][Full Text] [Related]  

  • 26. A suggested role for mitochondria in Noonan syndrome.
    Lee I; Pecinova A; Pecina P; Neel BG; Araki T; Kucherlapati R; Roberts AE; Hüttemann M
    Biochim Biophys Acta; 2010 Feb; 1802(2):275-83. PubMed ID: 19835954
    [TBL] [Abstract][Full Text] [Related]  

  • 27. The signaling adapter, FRS2, facilitates neuronal branching in primary cortical neurons via both Grb2- and Shp2-dependent mechanisms.
    Zhou L; Talebian A; Meakin SO
    J Mol Neurosci; 2015 Mar; 55(3):663-77. PubMed ID: 25159185
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Determination of the catalytic activity of LEOPARD syndrome-associated SHP2 mutants toward parafibromin, a bona fide SHP2 substrate involved in Wnt signaling.
    Noda S; Takahashi A; Hayashi T; Tanuma S; Hatakeyama M
    Biochem Biophys Res Commun; 2016 Jan; 469(4):1133-9. PubMed ID: 26742426
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Noonan and LEOPARD syndrome Shp2 variants induce heart displacement defects in zebrafish.
    Bonetti M; Paardekooper Overman J; Tessadori F; Noël E; Bakkers J; den Hertog J
    Development; 2014 May; 141(9):1961-70. PubMed ID: 24718990
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Noonan syndrome-causing SHP2 mutants impair ERK-dependent chondrocyte differentiation during endochondral bone growth.
    Tajan M; Pernin-Grandjean J; Beton N; Gennero I; Capilla F; Neel BG; Araki T; Valet P; Tauber M; Salles JP; Yart A; Edouard T
    Hum Mol Genet; 2018 Jul; 27(13):2276-2289. PubMed ID: 29659837
    [TBL] [Abstract][Full Text] [Related]  

  • 31. SHP2 Drives Adaptive Resistance to ERK Signaling Inhibition in Molecularly Defined Subsets of ERK-Dependent Tumors.
    Ahmed TA; Adamopoulos C; Karoulia Z; Wu X; Sachidanandam R; Aaronson SA; Poulikakos PI
    Cell Rep; 2019 Jan; 26(1):65-78.e5. PubMed ID: 30605687
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Severe Intellectual Disability and Enhanced Gamma-Aminobutyric Acidergic Synaptogenesis in a Novel Model of Rare RASopathies.
    Papale A; d'Isa R; Menna E; Cerovic M; Solari N; Hardingham N; Cambiaghi M; Cursi M; Barbacid M; Leocani L; Fasano S; Matteoli M; Brambilla R
    Biol Psychiatry; 2017 Feb; 81(3):179-192. PubMed ID: 27587266
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Canine histiocytic sarcoma cell lines with SHP2 p.Glu76Gln or p.Glu76Ala mutations are sensitive to allosteric SHP2 inhibitor SHP099.
    Tani H; Kurita S; Miyamoto R; Ochiai K; Tamura K; Bonkobara M
    Vet Comp Oncol; 2020 Jun; 18(2):161-168. PubMed ID: 31339650
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Mouse model of Noonan syndrome reveals cell type- and gene dosage-dependent effects of Ptpn11 mutation.
    Araki T; Mohi MG; Ismat FA; Bronson RT; Williams IR; Kutok JL; Yang W; Pao LI; Gilliland DG; Epstein JA; Neel BG
    Nat Med; 2004 Aug; 10(8):849-57. PubMed ID: 15273746
    [TBL] [Abstract][Full Text] [Related]  

  • 35. SHP2 sails from physiology to pathology.
    Tajan M; de Rocca Serra A; Valet P; Edouard T; Yart A
    Eur J Med Genet; 2015 Oct; 58(10):509-25. PubMed ID: 26341048
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Oncogenic Shp2 disturbs microtubule regulation to cause HDAC6-dependent ERK hyperactivation.
    Tien SC; Chang ZF
    Oncogene; 2014 May; 33(22):2938-46. PubMed ID: 23770849
    [TBL] [Abstract][Full Text] [Related]  

  • 37. SHP2 clinical phenotype, cancer, or RASopathies, can be predicted by mutant conformational propensities.
    Liu Y; Zhang W; Jang H; Nussinov R
    Cell Mol Life Sci; 2023 Dec; 81(1):5. PubMed ID: 38085330
    [TBL] [Abstract][Full Text] [Related]  

  • 38. PTPN11/Corkscrew Activates Local Presynaptic Mapk Signaling to Regulate Synapsin, Synaptic Vesicle Pools, and Neurotransmission Strength, with a Dual Requirement in Neurons and Glia.
    Leahy SN; Vita DJ; Broadie K
    J Neurosci; 2024 Apr; 44(17):. PubMed ID: 38471782
    [TBL] [Abstract][Full Text] [Related]  

  • 39. EGFR-activated Src family kinases maintain GAB1-SHP2 complexes distal from EGFR.
    Furcht CM; Buonato JM; Lazzara MJ
    Sci Signal; 2015 May; 8(376):ra46. PubMed ID: 25969544
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Sprouty2-modulated Kras signaling rescues Shp2 deficiency during lens and lacrimal gland development.
    Pan Y; Carbe C; Powers A; Feng GS; Zhang X
    Development; 2010 Apr; 137(7):1085-93. PubMed ID: 20215346
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 12.