396 related articles for article (PubMed ID: 30839208)
1. Proteasome Activation as a New Therapeutic Approach To Target Proteotoxic Disorders.
Njomen E; Tepe JJ
J Med Chem; 2019 Jul; 62(14):6469-6481. PubMed ID: 30839208
[TBL] [Abstract][Full Text] [Related]
2. Targeting the 26S Proteasome To Protect Against Proteotoxic Diseases.
Myeku N; Duff KE
Trends Mol Med; 2018 Jan; 24(1):18-29. PubMed ID: 29233753
[TBL] [Abstract][Full Text] [Related]
3. Advances in Proteasome Enhancement by Small Molecules.
George DE; Tepe JJ
Biomolecules; 2021 Nov; 11(12):. PubMed ID: 34944433
[TBL] [Abstract][Full Text] [Related]
4. Small-Molecule Degraders beyond PROTACs-Challenges and Opportunities.
Kastl JM; Davies G; Godsman E; Holdgate GA
SLAS Discov; 2021 Apr; 26(4):524-533. PubMed ID: 33632029
[TBL] [Abstract][Full Text] [Related]
5. Proteasome Activation to Combat Proteotoxicity.
Jones CL; Tepe JJ
Molecules; 2019 Aug; 24(15):. PubMed ID: 31387243
[TBL] [Abstract][Full Text] [Related]
6. Methods for the discovery of small molecules to monitor and perturb the activity of the human proteasome.
Maresh ME; Salazar-Chaparro AF; Trader DJ
Future Med Chem; 2021 Jan; 13(2):99-116. PubMed ID: 33275045
[TBL] [Abstract][Full Text] [Related]
7. High-Throughput Quantitative Assay Technologies for Accelerating the Discovery and Optimization of Targeted Protein Degradation Therapeutics.
Simard JR; Lee L; Vieux E; Improgo R; Tieu T; Phillips AJ; Fisher SL; Pollock RM; Park E
SLAS Discov; 2021 Apr; 26(4):503-517. PubMed ID: 33430712
[TBL] [Abstract][Full Text] [Related]
8. Small Molecule Modulation of Proteasome Assembly.
Njomen E; Osmulski PA; Jones CL; Gaczynska M; Tepe JJ
Biochemistry; 2018 Jul; 57(28):4214-4224. PubMed ID: 29897236
[TBL] [Abstract][Full Text] [Related]
9. The relationship between the 20S proteasomes and prion-mediated neurodegenerations: potential therapeutic opportunities.
Cecarini V; Bonfili L; Cuccioloni M; Mozzicafreddo M; Angeletti M; Eleuteri AM
Apoptosis; 2010 Nov; 15(11):1322-35. PubMed ID: 20213200
[TBL] [Abstract][Full Text] [Related]
10. Aim for the core: suitability of the ubiquitin-independent 20S proteasome as a drug target in neurodegeneration.
Opoku-Nsiah KA; Gestwicki JE
Transl Res; 2018 Aug; 198():48-57. PubMed ID: 30244692
[TBL] [Abstract][Full Text] [Related]
11. Targeted protein degradation and the enzymology of degraders.
Fisher SL; Phillips AJ
Curr Opin Chem Biol; 2018 Jun; 44():47-55. PubMed ID: 29885948
[TBL] [Abstract][Full Text] [Related]
12. Itraconazole Confers Cytoprotection Against Neurodegenerative Disease-Associated Abnormal Protein Aggregation.
Dubey AR; Mishra R; Jagtap YA; Kinger S; Kumar P; Dhiman R; Ghosh S; Singh S; Prasad A; Jana NR; Mishra A
Mol Neurobiol; 2023 May; 60(5):2397-2412. PubMed ID: 36656458
[TBL] [Abstract][Full Text] [Related]
13. Expanding the role of proteasome homeostasis in Parkinson's disease: beyond protein breakdown.
Bi M; Du X; Jiao Q; Chen X; Jiang H
Cell Death Dis; 2021 Feb; 12(2):154. PubMed ID: 33542205
[TBL] [Abstract][Full Text] [Related]
14. Small Molecule Enhancement of 20S Proteasome Activity Targets Intrinsically Disordered Proteins.
Jones CL; Njomen E; Sjögren B; Dexheimer TS; Tepe JJ
ACS Chem Biol; 2017 Sep; 12(9):2240-2247. PubMed ID: 28719185
[TBL] [Abstract][Full Text] [Related]
15. Degradation of misfolded proteins in neurodegenerative diseases: therapeutic targets and strategies.
Ciechanover A; Kwon YT
Exp Mol Med; 2015 Mar; 47(3):e147. PubMed ID: 25766616
[TBL] [Abstract][Full Text] [Related]
16. Ubiquitin-dependent and independent roles of SUMO in proteostasis.
Liebelt F; Vertegaal AC
Am J Physiol Cell Physiol; 2016 Aug; 311(2):C284-96. PubMed ID: 27335169
[TBL] [Abstract][Full Text] [Related]
17. The Vital Role of Proteomics in Characterizing Novel Protein Degraders.
Zhang AX; Cassidy K; Dahl G; Moreau K; Pachl F; Zuhl AM
SLAS Discov; 2021 Apr; 26(4):518-523. PubMed ID: 33615886
[TBL] [Abstract][Full Text] [Related]
18. Cellular Protein Aggregates: Formation, Biological Effects, and Ways of Elimination.
Wen JH; He XH; Feng ZS; Li DY; Tang JX; Liu HF
Int J Mol Sci; 2023 May; 24(10):. PubMed ID: 37239937
[TBL] [Abstract][Full Text] [Related]
19. Proteasome-mediated proteostasis: Novel medicinal and pharmacological strategies for diseases.
Mishra R; Upadhyay A; Prajapati VK; Mishra A
Med Res Rev; 2018 Sep; 38(6):1916-1973. PubMed ID: 29719055
[TBL] [Abstract][Full Text] [Related]
20. Regulation of proteasomes in prion disease.
Zhu T; Hayat Khan S; Zhao D; Yang L
Acta Biochim Biophys Sin (Shanghai); 2014 Jul; 46(7):531-9. PubMed ID: 24829398
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
