211 related articles for article (PubMed ID: 30841449)
1. 6PGD inhibition sensitizes hepatocellular carcinoma to chemotherapy via AMPK activation and metabolic reprogramming.
Chen H; Wu D; Bao L; Yin T; Lei D; Yu J; Tong X
Biomed Pharmacother; 2019 Mar; 111():1353-1358. PubMed ID: 30841449
[TBL] [Abstract][Full Text] [Related]
2. 6PGD Upregulation is Associated with Chemo- and Immuno-Resistance of Renal Cell Carcinoma via AMPK Signaling-Dependent NADPH-Mediated Metabolic Reprograming.
Cao J; Sun X; Zhang X; Chen D
Am J Med Sci; 2020 Sep; 360(3):279-286. PubMed ID: 32829780
[TBL] [Abstract][Full Text] [Related]
3. Inhibiting 6-phosphogluconate dehydrogenase selectively targets breast cancer through AMPK activation.
Yang X; Peng X; Huang J
Clin Transl Oncol; 2018 Sep; 20(9):1145-1152. PubMed ID: 29340974
[TBL] [Abstract][Full Text] [Related]
4. Inhibiting 6-phosphogluconate dehydrogenase enhances chemotherapy efficacy in cervical cancer via AMPK-independent inhibition of RhoA and Rac1.
Guo H; Xiang Z; Zhang Y; Sun D
Clin Transl Oncol; 2019 Apr; 21(4):404-411. PubMed ID: 30182212
[TBL] [Abstract][Full Text] [Related]
5. Inhibiting 6-phosphogluconate dehydrogenase reverses doxorubicin resistance in anaplastic thyroid cancer via inhibiting NADPH-dependent metabolic reprogramming.
Ma L; Cheng Q
Biochem Biophys Res Commun; 2018 Apr; 498(4):912-917. PubMed ID: 29534964
[TBL] [Abstract][Full Text] [Related]
6. HBx regulates fatty acid oxidation to promote hepatocellular carcinoma survival during metabolic stress.
Wang MD; Wu H; Huang S; Zhang HL; Qin CJ; Zhao LH; Fu GB; Zhou X; Wang XM; Tang L; Wen W; Yang W; Tang SH; Cao D; Guo LN; Zeng M; Wu MC; Yan HX; Wang HY
Oncotarget; 2016 Feb; 7(6):6711-26. PubMed ID: 26744319
[TBL] [Abstract][Full Text] [Related]
7. 6-Phosphogluconate dehydrogenase links oxidative PPP, lipogenesis and tumour growth by inhibiting LKB1-AMPK signalling.
Lin R; Elf S; Shan C; Kang HB; Ji Q; Zhou L; Hitosugi T; Zhang L; Zhang S; Seo JH; Xie J; Tucker M; Gu TL; Sudderth J; Jiang L; Mitsche M; DeBerardinis RJ; Wu S; Li Y; Mao H; Chen PR; Wang D; Chen GZ; Hurwitz SJ; Lonial S; Arellano ML; Khoury HJ; Khuri FR; Lee BH; Lei Q; Brat DJ; Ye K; Boggon TJ; He C; Kang S; Fan J; Chen J
Nat Cell Biol; 2015 Nov; 17(11):1484-96. PubMed ID: 26479318
[TBL] [Abstract][Full Text] [Related]
8. Regulation of SIRT1/AMPK axis is critically involved in gallotannin-induced senescence and impaired autophagy leading to cell death in hepatocellular carcinoma cells.
Kwon HY; Kim JH; Kim B; Srivastava SK; Kim SH
Arch Toxicol; 2018 Jan; 92(1):241-257. PubMed ID: 28676953
[TBL] [Abstract][Full Text] [Related]
9. 6-Phosphogluconate dehydrogenase fuels multiple aspects of cancer cells: From cancer initiation to metastasis and chemoresistance.
Sarfraz I; Rasul A; Hussain G; Shah MA; Zahoor AF; Asrar M; Selamoglu Z; Ji XY; Adem Ş; Sarker SD
Biofactors; 2020 Jul; 46(4):550-562. PubMed ID: 32039535
[TBL] [Abstract][Full Text] [Related]
10. Simvastatin-induced cell cycle arrest through inhibition of STAT3/SKP2 axis and activation of AMPK to promote p27 and p21 accumulation in hepatocellular carcinoma cells.
Wang ST; Ho HJ; Lin JT; Shieh JJ; Wu CY
Cell Death Dis; 2017 Feb; 8(2):e2626. PubMed ID: 28230855
[TBL] [Abstract][Full Text] [Related]
11. A feedback loop between the androgen receptor and 6-phosphogluoconate dehydrogenase (6PGD) drives prostate cancer growth.
Gillis JL; Hinneh JA; Ryan NK; Irani S; Moldovan M; Quek LE; Shrestha RK; Hanson AR; Xie J; Hoy AJ; Holst J; Centenera MM; Mills IG; Lynn DJ; Selth LA; Butler LM
Elife; 2021 Aug; 10():. PubMed ID: 34382934
[TBL] [Abstract][Full Text] [Related]
12. Targeting 6-phosphogluconate dehydrogenase in the oxidative PPP sensitizes leukemia cells to antimalarial agent dihydroartemisinin.
Elf S; Lin R; Xia S; Pan Y; Shan C; Wu S; Lonial S; Gaddh M; Arellano ML; Khoury HJ; Khuri FR; Lee BH; Boggon TJ; Fan J; Chen J
Oncogene; 2017 Jan; 36(2):254-262. PubMed ID: 27270429
[TBL] [Abstract][Full Text] [Related]
13. AMPK regulates NADPH homeostasis to promote tumour cell survival during energy stress.
Jeon SM; Chandel NS; Hay N
Nature; 2012 May; 485(7400):661-5. PubMed ID: 22660331
[TBL] [Abstract][Full Text] [Related]
14. Overexpression of NAD(P)H: Quinone Oxidoreductase 1 Inhibits Hepatocellular Carcinoma Cell Proliferation and Induced Apoptosis by Activating AMPK/PGC-1α Pathway.
Zhang X; Han K; Yuan DH; Meng CY
DNA Cell Biol; 2017 Apr; 36(4):256-263. PubMed ID: 28191864
[TBL] [Abstract][Full Text] [Related]
15. Prognostic significance of AMPK activation and therapeutic effects of metformin in hepatocellular carcinoma.
Zheng L; Yang W; Wu F; Wang C; Yu L; Tang L; Qiu B; Li Y; Guo L; Wu M; Feng G; Zou D; Wang H
Clin Cancer Res; 2013 Oct; 19(19):5372-80. PubMed ID: 23942093
[TBL] [Abstract][Full Text] [Related]
16. Targeting AMPK, mTOR and β-Catenin by Combined Metformin and Aspirin Therapy in HCC: An Appraisal in Egyptian HCC Patients.
Abdelmonsif DA; Sultan AS; El-Hadidy WF; Abdallah DM
Mol Diagn Ther; 2018 Feb; 22(1):115-127. PubMed ID: 29094287
[TBL] [Abstract][Full Text] [Related]
17. Inhibition of mitochondrial respiration overcomes hepatocellular carcinoma chemoresistance.
Sun Y; Xu H; Chen X; Li X; Luo B
Biochem Biophys Res Commun; 2019 Jan; 508(2):626-632. PubMed ID: 30522865
[TBL] [Abstract][Full Text] [Related]
18. TFAM depletion overcomes hepatocellular carcinoma resistance to doxorubicin and sorafenib through AMPK activation and mitochondrial dysfunction.
Zhu Y; Xu J; Hu W; Wang F; Zhou Y; Xu W; Gong W; Shao L
Gene; 2020 Aug; 753():144807. PubMed ID: 32461017
[TBL] [Abstract][Full Text] [Related]
19. ID1 promotes hepatocellular carcinoma proliferation and confers chemoresistance to oxaliplatin by activating pentose phosphate pathway.
Yin X; Tang B; Li JH; Wang Y; Zhang L; Xie XY; Zhang BH; Qiu SJ; Wu WZ; Ren ZG
J Exp Clin Cancer Res; 2017 Nov; 36(1):166. PubMed ID: 29169374
[TBL] [Abstract][Full Text] [Related]
20. Negative regulation of Sirtuin 1 by AMP-activated protein kinase promotes metformin-induced senescence in hepatocellular carcinoma xenografts.
Zhou X; Chen J; Chen L; Feng X; Liu Z; Hu L; Zeng Z; Jia X; Liang M; Shi B; Yi G; Liu J
Cancer Lett; 2017 Dec; 411():1-11. PubMed ID: 28964787
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]