194 related articles for article (PubMed ID: 30841456)
1. Chlorpromazine toxicity is associated with disruption of cell membrane integrity and initiation of a pro-inflammatory response in the HepaRG hepatic cell line.
Morgan K; Martucci N; Kozlowska A; Gamal W; Brzeszczyński F; Treskes P; Samuel K; Hayes P; Nelson L; Bagnaninchi P; Brzeszczynska J; Plevris J
Biomed Pharmacother; 2019 Mar; 111():1408-1416. PubMed ID: 30841456
[TBL] [Abstract][Full Text] [Related]
2. Oxidative stress plays a major role in chlorpromazine-induced cholestasis in human HepaRG cells.
Anthérieu S; Bachour-El Azzi P; Dumont J; Abdel-Razzak Z; Guguen-Guillouzo C; Fromenty B; Robin MA; Guillouzo A
Hepatology; 2013 Apr; 57(4):1518-29. PubMed ID: 23175273
[TBL] [Abstract][Full Text] [Related]
3. Impact of inflammation on chlorpromazine-induced cytotoxicity and cholestatic features in HepaRG cells.
Bachour-El Azzi P; Sharanek A; Abdel-Razzak Z; Antherieu S; Al-Attrache H; Savary CC; Lepage S; Morel I; Labbe G; Guguen-Guillouzo C; Guillouzo A
Drug Metab Dispos; 2014 Sep; 42(9):1556-66. PubMed ID: 25002748
[TBL] [Abstract][Full Text] [Related]
4. Biokinetics of chlorpromazine in primary rat and human hepatocytes and human HepaRG cells after repeated exposure.
Broeders JJ; Parmentier C; Truisi GL; Jossé R; Alexandre E; Savary CC; Hewitt PG; Mueller SO; Guillouzo A; Richert L; van Eijkeren JC; Hermens JL; Blaauboer BJ
Toxicol In Vitro; 2015 Dec; 30(1 Pt A):52-61. PubMed ID: 25458484
[TBL] [Abstract][Full Text] [Related]
5. Molecular cytotoxic mechanisms of chlorpromazine in isolated rat hepatocytes.
MacAllister SL; Young C; Guzdek A; Zhidkov N; O'Brien PJ
Can J Physiol Pharmacol; 2013 Jan; 91(1):56-63. PubMed ID: 23368734
[TBL] [Abstract][Full Text] [Related]
6. Transcriptomic hepatotoxicity signature of chlorpromazine after short- and long-term exposure in primary human sandwich cultures.
Parmentier C; Truisi GL; Moenks K; Stanzel S; Lukas A; Kopp-Schneider A; Alexandre E; Hewitt PG; Mueller SO; Richert L
Drug Metab Dispos; 2013 Oct; 41(10):1835-42. PubMed ID: 23913027
[TBL] [Abstract][Full Text] [Related]
7. Chlorpromazine-induced perturbations of bile acids and free fatty acids in cholestatic liver injury prevented by the Chinese herbal compound Yin-Chen-Hao-Tang.
Yang Q; Yang F; Tang X; Ding L; Xu Y; Xiong Y; Wang Z; Yang L
BMC Complement Altern Med; 2015 Apr; 15():122. PubMed ID: 25887351
[TBL] [Abstract][Full Text] [Related]
8. Organotypic 3D HepaRG Liver Model for Assessment of Drug-Induced Cholestasis.
Ramaiahgari SC; Ferguson SS
Methods Mol Biol; 2019; 1981():313-323. PubMed ID: 31016663
[TBL] [Abstract][Full Text] [Related]
9. Primary culture of rat hepatocytes as a model system of canalicular development, biliary secretion, and intrahepatic cholestasis. V. Disturbance of the cellular membrane and bile canalicular ultrastructure induced by chlorpromazine.
Jung W; Gebhardt R; Robenek H
Virchows Arch B Cell Pathol Incl Mol Pathol; 1985; 49(4):349-63. PubMed ID: 2867634
[TBL] [Abstract][Full Text] [Related]
10. Comparative Localization and Functional Activity of the Main Hepatobiliary Transporters in HepaRG Cells and Primary Human Hepatocytes.
Bachour-El Azzi P; Sharanek A; Burban A; Li R; Guével RL; Abdel-Razzak Z; Stieger B; Guguen-Guillouzo C; Guillouzo A
Toxicol Sci; 2015 May; 145(1):157-68. PubMed ID: 25690737
[TBL] [Abstract][Full Text] [Related]
11. HepaRG-Progenitor Cell Derived Hepatocytes Cultured in Bioartificial Livers Are Protected from Healthy- and Acute Liver Failure-Plasma Induced Toxicity.
van Wenum M; Treskes P; Adam AAA; van der Mark VA; Jongejan A; Moerland PD; van Gulik TM; Oude Elferink RPJ; Chamuleau RAFM; Hoekstra R
Cell Physiol Biochem; 2018; 48(5):2189-2204. PubMed ID: 30110678
[TBL] [Abstract][Full Text] [Related]
12. Effect of chlorpromazine on hepatic perfusion and bile secretory function in the isolated perfused rat liver.
Tavoloni N; Reed JS; Hruban Z; Boyer JL
J Lab Clin Med; 1979 Nov; 94(5):726-41. PubMed ID: 227976
[TBL] [Abstract][Full Text] [Related]
13. Effect of chlorpromazine on isolated rat hepatocytes.
Tsao SC; Iga T; Sugiyama Y; Hanano M
Biochem Pharmacol; 1982 Feb; 31(4):491-7. PubMed ID: 7066018
[TBL] [Abstract][Full Text] [Related]
14. Bile Acid-Induced Toxicity in HepaRG Cells Recapitulates the Response in Primary Human Hepatocytes.
Woolbright BL; McGill MR; Yan H; Jaeschke H
Basic Clin Pharmacol Toxicol; 2016 Feb; 118(2):160-7. PubMed ID: 26176423
[TBL] [Abstract][Full Text] [Related]
15. Treatment of mouse liver slices with cholestatic hepatotoxicants results in down-regulation of Fxr and its target genes.
Szalowska E; Stoopen G; Groot MJ; Hendriksen PJ; Peijnenburg AA
BMC Med Genomics; 2013 Oct; 6():39. PubMed ID: 24112857
[TBL] [Abstract][Full Text] [Related]
16. Hepatic 3D spheroid models for the detection and study of compounds with cholestatic liability.
Hendriks DF; Fredriksson Puigvert L; Messner S; Mortiz W; Ingelman-Sundberg M
Sci Rep; 2016 Oct; 6():35434. PubMed ID: 27759057
[TBL] [Abstract][Full Text] [Related]
17. Model Systems for Studying the Role of Canalicular Efflux Transporters in Drug-Induced Cholestatic Liver Disease.
Stieger B; Mahdi ZM
J Pharm Sci; 2017 Sep; 106(9):2295-2301. PubMed ID: 28385542
[TBL] [Abstract][Full Text] [Related]
18. Effect of chlorpromazine on hepatic transport of indocyanine green in rats.
Tsao SC; Sawada Y; Iga T; Hanano M
Biochem Pharmacol; 1983 Mar; 32(6):1105-12. PubMed ID: 6838656
[TBL] [Abstract][Full Text] [Related]
19. Effects of chlorpromazine on bilirubin metabolism and biliary secretion in the rat.
Knodell RG
Gastroenterology; 1975 Oct; 69(4):965-72. PubMed ID: 1175890
[TBL] [Abstract][Full Text] [Related]
20. In vitro biokinetics of chlorpromazine and the influence of different dose metrics on effect concentrations for cytotoxicity in Balb/c 3T3, Caco-2 and HepaRG cell cultures.
Broeders JJ; Blaauboer BJ; Hermens JL
Toxicol In Vitro; 2013 Apr; 27(3):1057-64. PubMed ID: 23376437
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
