These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

203 related articles for article (PubMed ID: 30847859)

  • 1. Human 2-Oxoglutarate Dehydrogenase and 2-Oxoadipate Dehydrogenase Both Generate Superoxide/H
    Jordan F; Nemeria N; Gerfen G
    Neurochem Res; 2019 Oct; 44(10):2325-2335. PubMed ID: 30847859
    [TBL] [Abstract][Full Text] [Related]  

  • 2. The mitochondrial 2-oxoadipate and 2-oxoglutarate dehydrogenase complexes share their E2 and E3 components for their function and both generate reactive oxygen species.
    Nemeria NS; Gerfen G; Nareddy PR; Yang L; Zhang X; Szostak M; Jordan F
    Free Radic Biol Med; 2018 Feb; 115():136-145. PubMed ID: 29191460
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Evidence for functional and regulatory cross-talk between the tricarboxylic acid cycle 2-oxoglutarate dehydrogenase complex and 2-oxoadipate dehydrogenase on the l-lysine, l-hydroxylysine and l-tryptophan degradation pathways from studies in vitro.
    Nemeria NS; Gerfen G; Yang L; Zhang X; Jordan F
    Biochim Biophys Acta Bioenerg; 2018 Sep; 1859(9):932-939. PubMed ID: 29752936
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Production of superoxide/hydrogen peroxide by the mitochondrial 2-oxoadipate dehydrogenase complex.
    Goncalves RL; Bunik VI; Brand MD
    Free Radic Biol Med; 2016 Feb; 91():247-55. PubMed ID: 26708453
    [TBL] [Abstract][Full Text] [Related]  

  • 5. The human Krebs cycle 2-oxoglutarate dehydrogenase complex creates an additional source of superoxide/hydrogen peroxide from 2-oxoadipate as alternative substrate.
    Nemeria NS; Gerfen G; Guevara E; Nareddy PR; Szostak M; Jordan F
    Free Radic Biol Med; 2017 Jul; 108():644-654. PubMed ID: 28435050
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Probing the E1o-E2o and E1a-E2o Interactions in Binary Subcomplexes of the Human 2-Oxoglutarate Dehydrogenase and 2-Oxoadipate Dehydrogenase Complexes by Chemical Cross-Linking Mass Spectrometry and Molecular Dynamics Simulation.
    Ozohanics O; Zhang X; Nemeria NS; Ambrus A; Jordan F
    Int J Mol Sci; 2023 Feb; 24(5):. PubMed ID: 36901986
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Structure-function analyses of the G729R 2-oxoadipate dehydrogenase genetic variant associated with a disorder of l-lysine metabolism.
    Zhang X; Nemeria NS; Leandro J; Houten S; Lazarus M; Gerfen G; Ozohanics O; Ambrus A; Nagy B; Brukh R; Jordan F
    J Biol Chem; 2020 Jun; 295(23):8078-8095. PubMed ID: 32303640
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Inhibition and Crystal Structure of the Human DHTKD1-Thiamin Diphosphate Complex.
    Leandro J; Khamrui S; Wang H; Suebsuwong C; Nemeria NS; Huynh K; Moustakim M; Secor C; Wang M; Dodatko T; Stauffer B; Wilson CG; Yu C; Arkin MR; Jordan F; Sanchez R; DeVita RJ; Lazarus MB; Houten SM
    ACS Chem Biol; 2020 Aug; 15(8):2041-2047. PubMed ID: 32633484
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Whole-exome sequencing uncovers oxidoreductases DHTKD1 and OGDHL as linkers between mitochondrial dysfunction and eosinophilic esophagitis.
    Sherrill JD; Kc K; Wang X; Wen T; Chamberlin A; Stucke EM; Collins MH; Abonia JP; Peng Y; Wu Q; Putnam PE; Dexheimer PJ; Aronow BJ; Kottyan LC; Kaufman KM; Harley JB; Huang T; Rothenberg ME
    JCI Insight; 2018 Apr; 3(8):. PubMed ID: 29669943
    [TBL] [Abstract][Full Text] [Related]  

  • 10. A multipronged approach unravels unprecedented protein-protein interactions in the human 2-oxoglutarate dehydrogenase multienzyme complex.
    Zhou J; Yang L; Ozohanics O; Zhang X; Wang J; Ambrus A; Arjunan P; Brukh R; Nemeria NS; Furey W; Jordan F
    J Biol Chem; 2018 Dec; 293(50):19213-19227. PubMed ID: 30323066
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Formation of reactive oxygen species by human and bacterial pyruvate and 2-oxoglutarate dehydrogenase multienzyme complexes reconstituted from recombinant components.
    Ambrus A; Nemeria NS; Torocsik B; Tretter L; Nilsson M; Jordan F; Adam-Vizi V
    Free Radic Biol Med; 2015 Dec; 89():642-50. PubMed ID: 26456061
    [TBL] [Abstract][Full Text] [Related]  

  • 12. The 2-oxoacid dehydrogenase complexes in mitochondria can produce superoxide/hydrogen peroxide at much higher rates than complex I.
    Quinlan CL; Goncalves RL; Hey-Mogensen M; Yadava N; Bunik VI; Brand MD
    J Biol Chem; 2014 Mar; 289(12):8312-25. PubMed ID: 24515115
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Sources of superoxide/H2O2 during mitochondrial proline oxidation.
    Goncalves RL; Rothschild DE; Quinlan CL; Scott GK; Benz CC; Brand MD
    Redox Biol; 2014; 2():901-9. PubMed ID: 25184115
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Functional Versatility of the Human 2-Oxoadipate Dehydrogenase in the L-Lysine Degradation Pathway toward Its Non-Cognate Substrate 2-Oxopimelic Acid.
    Nemeria NS; Nagy B; Sanchez R; Zhang X; Leandro J; Ambrus A; Houten SM; Jordan F
    Int J Mol Sci; 2022 Jul; 23(15):. PubMed ID: 35897808
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Protein S-glutathionylation alters superoxide/hydrogen peroxide emission from pyruvate dehydrogenase complex.
    O'Brien M; Chalker J; Slade L; Gardiner D; Mailloux RJ
    Free Radic Biol Med; 2017 May; 106():302-314. PubMed ID: 28242228
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Generation of superoxide and hydrogen peroxide by side reactions of mitochondrial 2-oxoacid dehydrogenase complexes in isolation and in cells.
    Bunik VI; Brand MD
    Biol Chem; 2018 Apr; 399(5):407-420. PubMed ID: 29337692
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Manganese ions enhance mitochondrial H
    Bonke E; Siebels I; Zwicker K; Dröse S
    Free Radic Biol Med; 2016 Oct; 99():43-53. PubMed ID: 27474449
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Production of reactive oxygen species in brain mitochondria: contribution by electron transport chain and non-electron transport chain sources.
    Adam-Vizi V
    Antioxid Redox Signal; 2005; 7(9-10):1140-9. PubMed ID: 16115017
    [TBL] [Abstract][Full Text] [Related]  

  • 19. DHTKD1 mutations cause 2-aminoadipic and 2-oxoadipic aciduria.
    Danhauser K; Sauer SW; Haack TB; Wieland T; Staufner C; Graf E; Zschocke J; Strom TM; Traub T; Okun JG; Meitinger T; Hoffmann GF; Prokisch H; Kölker S
    Am J Hum Genet; 2012 Dec; 91(6):1082-7. PubMed ID: 23141293
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Mitochondrial alpha-ketoglutarate dehydrogenase complex generates reactive oxygen species.
    Starkov AA; Fiskum G; Chinopoulos C; Lorenzo BJ; Browne SE; Patel MS; Beal MF
    J Neurosci; 2004 Sep; 24(36):7779-88. PubMed ID: 15356189
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.