BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

193 related articles for article (PubMed ID: 30851694)

  • 1. β-Carboline and N-hydroxycinnamamide hybrids as anticancer agents for drug-resistant hepatocellular carcinoma.
    Ling Y; Gao WJ; Ling C; Liu J; Meng C; Qian J; Liu S; Gan H; Wu H; Tao J; Dai H; Zhang Y
    Eur J Med Chem; 2019 Apr; 168():515-526. PubMed ID: 30851694
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Hydroxamic Acid Derivatives of β-Carboline/Hydroxycinnamic Acid Hybrids Inducing Apoptosis and Autophagy through the PI3K/Akt/mTOR Pathways.
    Ling Y; Li Y; Zhu R; Qian J; Liu J; Gao W; Meng C; Miao J; Xiong B; Qiu X; Ling C; Dai H; Zhang Y
    J Nat Prod; 2019 Jun; 82(6):1442-1450. PubMed ID: 31120744
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Development of novel β-carboline-based hydroxamate derivatives as HDAC inhibitors with antiproliferative and antimetastatic activities in human cancer cells.
    Ling Y; Guo J; Yang Q; Zhu P; Miao J; Gao W; Peng Y; Yang J; Xu K; Xiong B; Liu G; Tao J; Luo L; Zhu Q; Zhang Y
    Eur J Med Chem; 2018 Jan; 144():398-409. PubMed ID: 29288941
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Discovery of novel β-carboline/acylhydrazone hybrids as potent antitumor agents and overcome drug resistance.
    Li Y; Yan W; Yang J; Yang Z; Hu M; Bai P; Tang M; Chen L
    Eur J Med Chem; 2018 May; 152():516-526. PubMed ID: 29754076
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Design, synthesis and biological evaluation of coumarin-based N-hydroxycinnamamide derivatives as novel histone deacetylase inhibitors with anticancer activities.
    Ding J; Liu J; Zhang Z; Guo J; Cheng M; Wan Y; Wang R; Fang Y; Guan Z; Jin Y; Xie SS
    Bioorg Chem; 2020 Aug; 101():104023. PubMed ID: 32650178
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Synthesis and biological evaluation of novel 3,9-substituted β-carboline derivatives as anticancer agents.
    Chen YF; Lin YC; Chen JP; Chan HC; Hsu MH; Lin HY; Kuo SC; Huang LJ
    Bioorg Med Chem Lett; 2015 Sep; 25(18):3873-7. PubMed ID: 26235951
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Design, synthesis and biological evaluation of novel hybrids targeting mTOR and HDACs for potential treatment of hepatocellular carcinoma.
    Zhai S; Zhang H; Chen R; Wu J; Ai D; Tao S; Cai Y; Zhang JQ; Wang L
    Eur J Med Chem; 2021 Dec; 225():113824. PubMed ID: 34509167
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Synthesis and in vitro biological evaluation of hybrids from tetrahydro-β-carboline and hydroxylcinnamic acid as antitumor carcinoma agents.
    Lin Y; Xia X; Yao R; Ni L; Hu J; Guo W; Zhu B
    Chem Pharm Bull (Tokyo); 2014; 62(4):343-9. PubMed ID: 24695344
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Novel β-Carboline/Hydroxamic Acid Hybrids Targeting Both Histone Deacetylase and DNA Display High Anticancer Activity via Regulation of the p53 Signaling Pathway.
    Ling Y; Xu C; Luo L; Cao J; Feng J; Xue Y; Zhu Q; Ju C; Li F; Zhang Y; Zhang Y; Ling X
    J Med Chem; 2015 Dec; 58(23):9214-27. PubMed ID: 26555243
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Design and synthesis of parthenolide and 5-fluorouracil conjugates as potential anticancer agents against drug resistant hepatocellular carcinoma.
    Ding Y; Li S; Ge W; Liu Z; Zhang X; Wang M; Chen T; Chen Y; Zhang Q
    Eur J Med Chem; 2019 Dec; 183():111706. PubMed ID: 31553932
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Design, synthesis, and biological evaluation of β-carboline 1,3,4-oxadiazole based hybrids as HDAC inhibitors with potential antitumor effects.
    Tian C; Huang S; Xu Z; Liu W; Li D; Liu M; Zhu C; Wu L; Jiang X; Ding H; Zhao Q
    Bioorg Med Chem Lett; 2022 May; 64():128663. PubMed ID: 35272009
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Design and Synthesis of C3-Substituted β-Carboline-Based Histone Deacetylase Inhibitors with Potent Antitumor Activities.
    Ling Y; Feng J; Luo L; Guo J; Peng Y; Wang T; Ge X; Xu Q; Wang X; Dai H; Zhang Y
    ChemMedChem; 2017 May; 12(9):646-651. PubMed ID: 28425177
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Syntheses of novel β-carboline derivatives and the activities against five tumor-cell lines.
    Bai B; Li XY; Liu L; Li Y; Zhu HJ
    Bioorg Med Chem Lett; 2014 Jan; 24(1):96-8. PubMed ID: 24345445
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Novel Hybrid CHC from β-carboline and
    Miao J; Meng C; Wu H; Shan W; Wang H; Ling C; Zhang J; Yang T
    Front Pharmacol; 2020; 11():626065. PubMed ID: 33536926
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Development of 3-hydroxycinnamamide-based HDAC inhibitors with potent in vitro and in vivo anti-tumor activity.
    Li X; Hou J; Li X; Jiang Y; Liu X; Mu W; Jin Y; Zhang Y; Xu W
    Eur J Med Chem; 2015 Jan; 89():628-37. PubMed ID: 25462271
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Design and synthesis of some β-carboline derivatives as multi-target anticancer agents.
    Abdelsalam MA; AboulWafa OM; Badawey EA; El-Shoukrofy MS; El-Miligy MM; Gouda N
    Future Med Chem; 2018 Dec; 10(24):2791-2814. PubMed ID: 30539666
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Design, synthesis, molecular modelling, and biological evaluation of novel substituted pyrimidine derivatives as potential anticancer agents for hepatocellular carcinoma.
    Ahmed NM; Youns M; Soltan MK; Said AM
    J Enzyme Inhib Med Chem; 2019 Dec; 34(1):1110-1120. PubMed ID: 31117890
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Synthesis and evaluation of novel hybrids β-carboline-4-thiazolidinones as potential antitumor and antiviral agents.
    Barbosa VA; Baréa P; Mazia RS; Ueda-Nakamura T; Costa WFD; Foglio MA; Goes Ruiz ALT; Carvalho JE; Vendramini-Costa DB; Nakamura CV; Sarragiotto MH
    Eur J Med Chem; 2016 Nov; 124():1093-1104. PubMed ID: 27792980
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Synthesis of novel diflunisal hydrazide-hydrazones as anti-hepatitis C virus agents and hepatocellular carcinoma inhibitors.
    Şenkardeş S; Kaushik-Basu N; Durmaz İ; Manvar D; Basu A; Atalay R; Küçükgüzel ŞG
    Eur J Med Chem; 2016 Jan; 108():301-308. PubMed ID: 26695731
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Design, synthesis and biological evaluation of novel 2-aminobenzamides containing dithiocarbamate moiety as histone deacetylase inhibitors and potent antitumor agents.
    Xie R; Li Y; Tang P; Yuan Q
    Eur J Med Chem; 2018 Jan; 143():320-333. PubMed ID: 29202397
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.