BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

230 related articles for article (PubMed ID: 30856011)

  • 1. Binding site comparisons for target-centered drug discovery.
    Konc J
    Expert Opin Drug Discov; 2019 May; 14(5):445-454. PubMed ID: 30856011
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Local Alignment of Ligand Binding Sites in Proteins for Polypharmacology and Drug Repositioning.
    Brylinski M
    Methods Mol Biol; 2017; 1611():109-122. PubMed ID: 28451975
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Computational polypharmacology: a new paradigm for drug discovery.
    Chaudhari R; Tan Z; Huang B; Zhang S
    Expert Opin Drug Discov; 2017 Mar; 12(3):279-291. PubMed ID: 28067061
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Computational drug repurposing to predict approved and novel drug-disease associations.
    Khalid Z; Sezerman OU
    J Mol Graph Model; 2018 Oct; 85():91-96. PubMed ID: 30130693
    [TBL] [Abstract][Full Text] [Related]  

  • 5. The development of novel polypharmacological agents targeting the multiple binding sites of nicotinic acetylcholine receptors.
    Reyes-Parada M; Iturriaga-Vasquez P
    Expert Opin Drug Discov; 2016 Oct; 11(10):969-81. PubMed ID: 27552487
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Predicting targeted polypharmacology for drug repositioning and multi- target drug discovery.
    Liu X; Zhu F; Ma XH; Shi Z; Yang SY; Wei YQ; Chen YZ
    Curr Med Chem; 2013; 20(13):1646-61. PubMed ID: 23410165
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Polypharmacology rescored: protein-ligand interaction profiles for remote binding site similarity assessment.
    Salentin S; Haupt VJ; Daminelli S; Schroeder M
    Prog Biophys Mol Biol; 2014; 116(2-3):174-86. PubMed ID: 24923864
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Updates to Binding MOAD (Mother of All Databases): Polypharmacology Tools and Their Utility in Drug Repurposing.
    Smith RD; Clark JJ; Ahmed A; Orban ZJ; Dunbar JB; Carlson HA
    J Mol Biol; 2019 Jun; 431(13):2423-2433. PubMed ID: 31125569
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Improving the efficacy-safety balance of polypharmacology in multi-target drug discovery.
    Ravikumar B; Aittokallio T
    Expert Opin Drug Discov; 2018 Feb; 13(2):179-192. PubMed ID: 29233023
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Drug Repurposing: An Emerging Tool for Drug Reuse, Recycling and Discovery.
    Roy S; Dhaneshwar S; Bhasin B
    Curr Drug Res Rev; 2021; 13(2):101-119. PubMed ID: 33573567
    [TBL] [Abstract][Full Text] [Related]  

  • 11. The polypharmacology of natural products.
    Ho TT; Tran QT; Chai CL
    Future Med Chem; 2018 Jun; 10(11):1361-1368. PubMed ID: 29673257
    [TBL] [Abstract][Full Text] [Related]  

  • 12. In silico methods to address polypharmacology: current status, applications and future perspectives.
    Lavecchia A; Cerchia C
    Drug Discov Today; 2016 Feb; 21(2):288-98. PubMed ID: 26743596
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Discovery of natural products with metal-binding properties as promising antibacterial agents.
    Dandawate P; Padhye S; Schobert R; Biersack B
    Expert Opin Drug Discov; 2019 Jun; 14(6):563-576. PubMed ID: 30905202
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Turning liabilities into opportunities: Off-target based drug repurposing in cancer.
    Palve V; Liao Y; Remsing Rix LL; Rix U
    Semin Cancer Biol; 2021 Jan; 68():209-229. PubMed ID: 32044472
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Exploring Polypharmacology in Drug Discovery and Repurposing Using the CANDO Platform.
    Chopra G; Samudrala R
    Curr Pharm Des; 2016; 22(21):3109-23. PubMed ID: 27013226
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Challenges and opportunities with drug repurposing: finding strategies to find alternative uses of therapeutics.
    Talevi A; Bellera CL
    Expert Opin Drug Discov; 2020 Apr; 15(4):397-401. PubMed ID: 31847616
    [No Abstract]   [Full Text] [Related]  

  • 17. Are we seeing a resurgence in the use of natural products for new drug discovery?
    Li F; Wang Y; Li D; Chen Y; Dou QP
    Expert Opin Drug Discov; 2019 May; 14(5):417-420. PubMed ID: 30810395
    [No Abstract]   [Full Text] [Related]  

  • 18. Advances and Challenges in Computational Target Prediction.
    Sydow D; Burggraaff L; Szengel A; van Vlijmen HWT; IJzerman AP; van Westen GJP; Volkamer A
    J Chem Inf Model; 2019 May; 59(5):1728-1742. PubMed ID: 30817146
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Polypharmacology in Drug Discovery: A Review from Systems Pharmacology Perspective.
    Zhang W; Bai Y; Wang Y; Xiao W
    Curr Pharm Des; 2016; 22(21):3171-81. PubMed ID: 26907941
    [TBL] [Abstract][Full Text] [Related]  

  • 20. In Silico Oncology Drug Repositioning and Polypharmacology.
    Cheng F
    Methods Mol Biol; 2019; 1878():243-261. PubMed ID: 30378081
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 12.