124 related articles for article (PubMed ID: 30857246)
1. Target Identification of the Marine Natural Products Dictyoceratin-A and -C as Selective Growth Inhibitors in Cancer Cells Adapted to Hypoxic Environments.
Kawachi T; Tanaka S; Fukuda A; Sumii Y; Setiawan A; Kotoku N; Kobayashi M; Arai M
Mar Drugs; 2019 Mar; 17(3):. PubMed ID: 30857246
[TBL] [Abstract][Full Text] [Related]
2. Marine spongian sesquiterpene phenols, dictyoceratin-C and smenospondiol, display hypoxia-selective growth inhibition against cancer cells.
Arai M; Kawachi T; Sato H; Setiawan A; Kobayashi M
Bioorg Med Chem Lett; 2014 Jul; 24(14):3155-7. PubMed ID: 24865416
[TBL] [Abstract][Full Text] [Related]
3. Structure-Activity Relationship and in Vivo Anti-Tumor Evaluations of Dictyoceratin-A and -C, Hypoxia-Selective Growth Inhibitors from Marine Sponge.
Sumii Y; Kotoku N; Fukuda A; Kawachi T; Arai M; Kobayashi M
Mar Drugs; 2015 Dec; 13(12):7419-32. PubMed ID: 26694423
[TBL] [Abstract][Full Text] [Related]
4. Enantioselective synthesis of dictyoceratin-A (smenospondiol) and -C, hypoxia-selective growth inhibitors from marine sponge.
Sumii Y; Kotoku N; Fukuda A; Kawachi T; Sumii Y; Arai M; Kobayashi M
Bioorg Med Chem; 2015 Mar; 23(5):966-75. PubMed ID: 25659617
[TBL] [Abstract][Full Text] [Related]
5. Furospinosulin-1, Marine Spongean Furanosesterterpene, Suppresses the Growth of Hypoxia-Adapted Cancer Cells by Binding to Transcriptional Regulators p54(nrb) and LEDGF/p75.
Arai M; Kawachi T; Kotoku N; Nakata C; Kamada H; Tsunoda S; Tsutsumi Y; Endo H; Inoue M; Sato H; Kobayashi M
Chembiochem; 2016 Jan; 17(2):181-9. PubMed ID: 26561285
[TBL] [Abstract][Full Text] [Related]
6. Identification of thioredoxin-interacting protein 1 as a hypoxia-inducible factor 1alpha-induced gene in pancreatic cancer.
Baker AF; Koh MY; Williams RR; James B; Wang H; Tate WR; Gallegos A; Von Hoff DD; Han H; Powis G
Pancreas; 2008 Mar; 36(2):178-86. PubMed ID: 18376310
[TBL] [Abstract][Full Text] [Related]
7. Identification of novel small molecule inhibitors of hypoxia-inducible factor-1 that differentially block hypoxia-inducible factor-1 activity and hypoxia-inducible factor-1alpha induction in response to hypoxic stress and growth factors.
Chau NM; Rogers P; Aherne W; Carroll V; Collins I; McDonald E; Workman P; Ashcroft M
Cancer Res; 2005 Jun; 65(11):4918-28. PubMed ID: 15930314
[TBL] [Abstract][Full Text] [Related]
8. Hypoxia-inducible factor-1 up-regulates the expression of Toll-like receptor 4 in pancreatic cancer cells under hypoxic conditions.
Fan P; Zhang JJ; Wang B; Wu HQ; Zhou SX; Wang CY; Zhang JH; Tian Y; Wu HS
Pancreatology; 2012; 12(2):170-8. PubMed ID: 22487528
[TBL] [Abstract][Full Text] [Related]
9. Cell type-specific, topoisomerase II-dependent inhibition of hypoxia-inducible factor-1alpha protein accumulation by NSC 644221.
Creighton-Gutteridge M; Cardellina JH; Stephen AG; Rapisarda A; Uranchimeg B; Hite K; Denny WA; Shoemaker RH; Melillo G
Clin Cancer Res; 2007 Feb; 13(3):1010-8. PubMed ID: 17289897
[TBL] [Abstract][Full Text] [Related]
10. [Impact of RNA interference targeting hypoxia-inducible factor-1alpha on chemosensitivity in esophageal squamous cell carcinoma cells under hypoxia].
Wu XA; Sun Y; Fan QX; Wang LX; Wang RL; Zhang L
Zhonghua Yi Xue Za Zhi; 2007 Oct; 87(37):2640-4. PubMed ID: 18162154
[TBL] [Abstract][Full Text] [Related]
11. The Apoptotic Effect of HIF-1α Inhibition Combined with Glucose plus Insulin Treatment on Gastric Cancer under Hypoxic Conditions.
Tanaka T; Kitajima Y; Miyake S; Yanagihara K; Hara H; Nishijima-Matsunobu A; Baba K; Shida M; Wakiyama K; Nakamura J; Noshiro H
PLoS One; 2015; 10(9):e0137257. PubMed ID: 26339797
[TBL] [Abstract][Full Text] [Related]
12. The inhibitory effect of hypoxic cytotoxin on the expansion of cancer stem cells in ovarian cancer.
Nozawa-Suzuki N; Nagasawa H; Ohnishi K; Morishige K
Biochem Biophys Res Commun; 2015 Feb; 457(4):706-11. PubMed ID: 25619133
[TBL] [Abstract][Full Text] [Related]
13. Knockdown of hypoxia-inducible factor-1 alpha reduces proliferation, induces apoptosis and attenuates the aggressive phenotype of retinoblastoma WERI-Rb-1 cells under hypoxic conditions.
Xia T; Cheng H; Zhu Y
Ann Clin Lab Sci; 2014; 44(2):134-44. PubMed ID: 24795051
[TBL] [Abstract][Full Text] [Related]
14. Kamebakaurin inhibits the expression of hypoxia-inducible factor-1α and its target genes to confer antitumor activity.
Wang KS; Ma J; Mi C; Li J; Lee JJ; Jin X
Oncol Rep; 2016 Apr; 35(4):2045-52. PubMed ID: 26781327
[TBL] [Abstract][Full Text] [Related]
15. Targeting hypoxia-inducible factor 1 (HIF-1) signaling with natural products toward cancer chemotherapy.
Ikeda H; Kakeya H
J Antibiot (Tokyo); 2021 Oct; 74(10):687-695. PubMed ID: 34331027
[TBL] [Abstract][Full Text] [Related]
16. Silibinin inhibits hypoxia-induced HIF-1α-mediated signaling, angiogenesis and lipogenesis in prostate cancer cells: In vitro evidence and in vivo functional imaging and metabolomics.
Deep G; Kumar R; Nambiar DK; Jain AK; Ramteke AM; Serkova NJ; Agarwal C; Agarwal R
Mol Carcinog; 2017 Mar; 56(3):833-848. PubMed ID: 27533043
[TBL] [Abstract][Full Text] [Related]
17. An Akt/hypoxia-inducible factor-1alpha/platelet-derived growth factor-BB autocrine loop mediates hypoxia-induced chemoresistance in liver cancer cells and tumorigenic hepatic progenitor cells.
Lau CK; Yang ZF; Ho DW; Ng MN; Yeoh GC; Poon RT; Fan ST
Clin Cancer Res; 2009 May; 15(10):3462-71. PubMed ID: 19447872
[TBL] [Abstract][Full Text] [Related]
18. Cyclin-dependent kinase inhibitor, P276-00, inhibits HIF-1α and induces G2/M arrest under hypoxia in prostate cancer cells.
Manohar SM; Padgaonkar AA; Jalota-Badhwar A; Rao SV; Joshi KS
Prostate Cancer Prostatic Dis; 2012 Mar; 15(1):15-27. PubMed ID: 22083267
[TBL] [Abstract][Full Text] [Related]
19. YC-1: a potential anticancer drug targeting hypoxia-inducible factor 1.
Yeo EJ; Chun YS; Cho YS; Kim J; Lee JC; Kim MS; Park JW
J Natl Cancer Inst; 2003 Apr; 95(7):516-25. PubMed ID: 12671019
[TBL] [Abstract][Full Text] [Related]
20. Topotecan inhibits vascular endothelial growth factor production and angiogenic activity induced by hypoxia in human neuroblastoma by targeting hypoxia-inducible factor-1alpha and -2alpha.
Puppo M; Battaglia F; Ottaviano C; Delfino S; Ribatti D; Varesio L; Bosco MC
Mol Cancer Ther; 2008 Jul; 7(7):1974-84. PubMed ID: 18645007
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]