165 related articles for article (PubMed ID: 30863481)
1. Apatinib Promotes Apoptosis of Pancreatic Cancer Cells through Downregulation of Hypoxia-Inducible Factor-1
He K; Wu L; Ding Q; Haider F; Yu H; Wang H; Xiang G
Oxid Med Cell Longev; 2019; 2019():5152072. PubMed ID: 30863481
[TBL] [Abstract][Full Text] [Related]
2. Apatinib Inhibits Angiogenesis in Intrahepatic Cholangiocarcinoma by Regulating the Vascular Endothelial Growth Factor Receptor-2/Signal Transducer and Activator of Transcription Factor 3/Hypoxia Inducible Factor 1 Subunit Alpha Signaling Axis.
Huang MP; Gu SZ; Huang B; Li GW; Xiong ZP; Tang T; Zeng SN
Pharmacology; 2021; 106(9-10):509-519. PubMed ID: 34412054
[TBL] [Abstract][Full Text] [Related]
3. Apatinib triggers autophagic and apoptotic cell death via VEGFR2/STAT3/PD-L1 and ROS/Nrf2/p62 signaling in lung cancer.
Xie C; Zhou X; Liang C; Li X; Ge M; Chen Y; Yin J; Zhu J; Zhong C
J Exp Clin Cancer Res; 2021 Aug; 40(1):266. PubMed ID: 34429133
[TBL] [Abstract][Full Text] [Related]
4. Identification of thioredoxin-interacting protein 1 as a hypoxia-inducible factor 1alpha-induced gene in pancreatic cancer.
Baker AF; Koh MY; Williams RR; James B; Wang H; Tate WR; Gallegos A; Von Hoff DD; Han H; Powis G
Pancreas; 2008 Mar; 36(2):178-86. PubMed ID: 18376310
[TBL] [Abstract][Full Text] [Related]
5. Excess glucose induces hypoxia-inducible factor-1α in pancreatic cancer cells and stimulates glucose metabolism and cell migration.
Liu Z; Jia X; Duan Y; Xiao H; Sundqvist KG; Permert J; Wang F
Cancer Biol Ther; 2013 May; 14(5):428-35. PubMed ID: 23377827
[TBL] [Abstract][Full Text] [Related]
6. Knockdown of Hypoxia-Inducible Factor 1α (HIF-1α) Promotes Autophagy and Inhibits Phosphatidylinositol 3-Kinase (PI3K)/AKT/Mammalian Target of Rapamycin (mTOR) Signaling Pathway in Ovarian Cancer Cells.
Huang J; Gao L; Li B; Liu C; Hong S; Min J; Hong L
Med Sci Monit; 2019 Jun; 25():4250-4263. PubMed ID: 31175269
[TBL] [Abstract][Full Text] [Related]
7. An undesired effect of chemotherapy: gemcitabine promotes pancreatic cancer cell invasiveness through reactive oxygen species-dependent, nuclear factor κB- and hypoxia-inducible factor 1α-mediated up-regulation of CXCR4.
Arora S; Bhardwaj A; Singh S; Srivastava SK; McClellan S; Nirodi CS; Piazza GA; Grizzle WE; Owen LB; Singh AP
J Biol Chem; 2013 Jul; 288(29):21197-21207. PubMed ID: 23740244
[TBL] [Abstract][Full Text] [Related]
8. Autophagy inhibitor potentiates the antitumor efficacy of apatinib in uterine sarcoma by stimulating PI3K/Akt/mTOR pathway.
Chen S; Yao L
Cancer Chemother Pharmacol; 2021 Aug; 88(2):323-334. PubMed ID: 33978839
[TBL] [Abstract][Full Text] [Related]
9. [The inhibition effects of apatinib on cell proliferation, migration and apoptosis in esophageal carcinoma via Ras/Raf/MEK/ERK and JAK2/STAT3 pathways].
Feng Y; Zhou MY; Sun F; Kong Z; Wang J; Sun ZQ; Hu LJ; Wang JL; Hua Q; Yu JP
Zhonghua Zhong Liu Za Zhi; 2019 Apr; 41(4):263-275. PubMed ID: 31014051
[No Abstract] [Full Text] [Related]
10. Effects of YC-1 on hypoxia-inducible factor 1 alpha in hypoxic human bladder transitional carcinoma cell line T24 cells.
Li Y; Zhao X; Tang H; Zhong Z; Zhang L; Xu R; Li S; Wang Y
Urol Int; 2012; 88(1):95-101. PubMed ID: 22041818
[TBL] [Abstract][Full Text] [Related]
11. Apatinib suppresses the Proliferation and Apoptosis of Gastric Cancer Cells via the PI3K/Akt Signaling Pathway.
Jia X; Wen Z; Sun Q; Zhao X; Yang H; Shi X; Xin T
J BUON; 2019; 24(5):1985-1991. PubMed ID: 31786865
[TBL] [Abstract][Full Text] [Related]
12. Signal pathway of hypoxia-inducible factor-1alpha phosphorylation and its interaction with von Hippel-Lindau tumor suppressor protein during ischemia in MiaPaCa-2 pancreatic cancer cells.
Kwon SJ; Song JJ; Lee YJ
Clin Cancer Res; 2005 Nov; 11(21):7607-13. PubMed ID: 16278378
[TBL] [Abstract][Full Text] [Related]
13. Apatinib, a Novel Tyrosine Kinase Inhibitor, Promotes ROS-Dependent Apoptosis and Autophagy via the Nrf2/HO-1 Pathway in Ovarian Cancer Cells.
Sun X; Li J; Li Y; Wang S; Li Q
Oxid Med Cell Longev; 2020; 2020():3145182. PubMed ID: 32509141
[TBL] [Abstract][Full Text] [Related]
14. GDC-0941 inhibits metastatic characteristics of thyroid carcinomas by targeting both the phosphoinositide-3 kinase (PI3K) and hypoxia-inducible factor-1α (HIF-1α) pathways.
Burrows N; Babur M; Resch J; Ridsdale S; Mejin M; Rowling EJ; Brabant G; Williams KJ
J Clin Endocrinol Metab; 2011 Dec; 96(12):E1934-43. PubMed ID: 21994956
[TBL] [Abstract][Full Text] [Related]
15. Shikonin suppresses proliferation and induces cell cycle arrest through the inhibition of hypoxia-inducible factor-1α signaling.
Li MY; Mi C; Wang KS; Wang Z; Zuo HX; Piao LX; Xu GH; Li X; Ma J; Jin X
Chem Biol Interact; 2017 Aug; 274():58-67. PubMed ID: 28684144
[TBL] [Abstract][Full Text] [Related]
16. Perillyl alcohol efficiently scavenges activity of cellular ROS and inhibits the translational expression of hypoxia-inducible factor-1α via mTOR/4E-BP1 signaling pathways.
Ma J; Li J; Wang KS; Mi C; Piao LX; Xu GH; Li X; Lee JJ; Jin X
Int Immunopharmacol; 2016 Oct; 39():1-9. PubMed ID: 27394002
[TBL] [Abstract][Full Text] [Related]
17. Effects of YC-1 on hypoxia-inducible factor 1-driven transcription activity, cell proliferative vitality, and apoptosis in hypoxic human pancreatic cancer cells.
Zhao Q; Du J; Gu H; Teng X; Zhang Q; Qin H; Liu N
Pancreas; 2007 Mar; 34(2):242-7. PubMed ID: 17312464
[TBL] [Abstract][Full Text] [Related]
18. The novel hypoxic cytotoxin, TX-2098 has antitumor effect in pancreatic cancer; possible mechanism through inhibiting VEGF and hypoxia inducible factor-1α targeted gene expression.
Miyake K; Nishioka M; Imura S; Batmunkh E; Uto Y; Nagasawa H; Hori H; Shimada M
Exp Cell Res; 2012 Aug; 318(13):1554-63. PubMed ID: 22472348
[TBL] [Abstract][Full Text] [Related]
19. Apatinib promotes autophagy and apoptosis through VEGFR2/STAT3/BCL-2 signaling in osteosarcoma.
Liu K; Ren T; Huang Y; Sun K; Bao X; Wang S; Zheng B; Guo W
Cell Death Dis; 2017 Aug; 8(8):e3015. PubMed ID: 28837148
[TBL] [Abstract][Full Text] [Related]
20. Ras inhibitors display an anti-metastatic effect by downregulation of lysyl oxidase through inhibition of the Ras-PI3K-Akt-HIF-1α pathway.
Yoshikawa Y; Takano O; Kato I; Takahashi Y; Shima F; Kataoka T
Cancer Lett; 2017 Dec; 410():82-91. PubMed ID: 28951129
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]