These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
105 related articles for article (PubMed ID: 30869527)
1. In Silico Screening to Identify Inhibitors of Growth Factor Receptor 2-Focal Adhesion Kinase Interaction for Therapeutic Treatment of Pathological Cardiac Hypertrophy. Mohanty P; Bhatnagar S Assay Drug Dev Technol; 2019; 17(2):58-67. PubMed ID: 30869527 [TBL] [Abstract][Full Text] [Related]
2. Structural basis of focal adhesion targeting domain-mediated signaling in cardiac hypertrophy. Mohanty P; Bhatnagar S J Recept Signal Transduct Res; 2017 Feb; 37(1):38-50. PubMed ID: 27056381 [TBL] [Abstract][Full Text] [Related]
3. Structure of focal adhesion kinase in healthy heart versus pathological cardiac hypertrophy: A modeling and simulation study. Mohanty P; Bhatnagar S J Mol Graph Model; 2018 Mar; 80():15-24. PubMed ID: 29306139 [TBL] [Abstract][Full Text] [Related]
4. Computational insights into allosteric inhibition of focal adhesion kinase: A combined pharmacophore modeling and molecular dynamics approach. Kumar V; Singh P; Parate S; Singh R; Ro HS; Song KS; Lee KW; Park YM J Mol Graph Model; 2024 Jul; 130():108789. PubMed ID: 38718434 [TBL] [Abstract][Full Text] [Related]
5. Discovery of a novel nonphosphorylated pentapeptide motif displaying high affinity for Grb2-SH2 domain by the utilization of 3'-substituted tyrosine derivatives. Song YL; Peach ML; Roller PP; Qiu S; Wang S; Long YQ J Med Chem; 2006 Mar; 49(5):1585-96. PubMed ID: 16509576 [TBL] [Abstract][Full Text] [Related]
6. Involvement of proline-rich tyrosine kinase 2 in platelet activation: tyrosine phosphorylation mostly dependent on alphaIIbbeta3 integrin and protein kinase C, translocation to the cytoskeleton and association with Shc through Grb2. Ohmori T; Yatomi Y; Asazuma N; Satoh K; Ozaki Y Biochem J; 2000 Apr; 347(Pt 2):561-9. PubMed ID: 10749687 [TBL] [Abstract][Full Text] [Related]
7. Computational-based discovery of FAK FERM domain chemical probes that inhibit HER2-FAK cancer signaling. Stahl E; Nott R; Koessel K; Cance W; Marlowe T Chem Biol Drug Des; 2020 Jun; 95(6):584-599. PubMed ID: 32080977 [TBL] [Abstract][Full Text] [Related]
8. Integrin-mediated signal transduction linked to Ras pathway by GRB2 binding to focal adhesion kinase. Schlaepfer DD; Hanks SK; Hunter T; van der Geer P Nature; 1994 Dec 22-29; 372(6508):786-91. PubMed ID: 7997267 [TBL] [Abstract][Full Text] [Related]
9. Progress in the Development of Small Molecular Inhibitors of Focal Adhesion Kinase (FAK). Lu Y; Sun H J Med Chem; 2020 Dec; 63(23):14382-14403. PubMed ID: 33058670 [TBL] [Abstract][Full Text] [Related]
10. Differential regulation of cell migration and cell cycle progression by FAK complexes with Src, PI3K, Grb7 and Grb2 in focal contacts. Shen TL; Guan JL FEBS Lett; 2001 Jun; 499(1-2):176-81. PubMed ID: 11418135 [TBL] [Abstract][Full Text] [Related]
11. Identification of novel PI3Kδ inhibitors by docking, ADMET prediction and molecular dynamics simulations. Liu YY; Feng XY; Jia WQ; Jing Z; Xu WR; Cheng XC Comput Biol Chem; 2019 Feb; 78():190-204. PubMed ID: 30557817 [TBL] [Abstract][Full Text] [Related]
12. An integrated in silico screening strategy for identifying promising disruptors of p53-MDM2 interaction. Sirous H; Chemi G; Campiani G; Brogi S Comput Biol Chem; 2019 Dec; 83():107105. PubMed ID: 31473433 [TBL] [Abstract][Full Text] [Related]
13. Compounds identified by virtual docking to a tetrameric EGFR extracellular domain can modulate Grb2 internalization. Ramirez UD; Nikonova AS; Liu H; Pecherskaya A; Lawrence SH; Serebriiskii IG; Zhou Y; Robinson MK; Einarson MB; Golemis EA; Jaffe EK BMC Cancer; 2015 May; 15():436. PubMed ID: 26016476 [TBL] [Abstract][Full Text] [Related]
14. Vascular endothelial growth factor induces activation and subcellular translocation of focal adhesion kinase (p125FAK) in cultured rat cardiac myocytes. Takahashi N; Seko Y; Noiri E; Tobe K; Kadowaki T; Sabe H; Yazaki Y Circ Res; 1999 May; 84(10):1194-202. PubMed ID: 10347094 [TBL] [Abstract][Full Text] [Related]
15. Design, synthesis, and biological evaluation of novel FAK scaffold inhibitors targeting the FAK-VEGFR3 protein-protein interaction. Gogate PN; Ethirajan M; Kurenova EV; Magis AT; Pandey RK; Cance WG Eur J Med Chem; 2014 Jun; 80():154-166. PubMed ID: 24780592 [TBL] [Abstract][Full Text] [Related]
16. Fragment-based discovery of focal adhesion kinase inhibitors. Grädler U; Bomke J; Musil D; Dresing V; Lehmann M; Hölzemann G; Greiner H; Esdar C; Krier M; Heinrich T Bioorg Med Chem Lett; 2013 Oct; 23(19):5401-9. PubMed ID: 23973211 [TBL] [Abstract][Full Text] [Related]
17. The role of the Grb2-p38 MAPK signaling pathway in cardiac hypertrophy and fibrosis. Zhang S; Weinheimer C; Courtois M; Kovacs A; Zhang CE; Cheng AM; Wang Y; Muslin AJ J Clin Invest; 2003 Mar; 111(6):833-41. PubMed ID: 12639989 [TBL] [Abstract][Full Text] [Related]
18. An in silico high-throughput screen identifies potential selective inhibitors for the non-receptor tyrosine kinase Pyk2. Meirson T; Samson AO; Gil-Henn H Drug Des Devel Ther; 2017; 11():1535-1557. PubMed ID: 28572720 [TBL] [Abstract][Full Text] [Related]
19. Focal adhesion kinase and p130Cas mediate both sarcomeric organization and activation of genes associated with cardiac myocyte hypertrophy. Kovacic-Milivojević B; Roediger F; Almeida EA; Damsky CH; Gardner DG; Ilić D Mol Biol Cell; 2001 Aug; 12(8):2290-307. PubMed ID: 11514617 [TBL] [Abstract][Full Text] [Related]
20. Crystal structures of the SH2 domain of Grb2: highlight on the binding of a new high-affinity inhibitor. Nioche P; Liu WQ; Broutin I; Charbonnier F; Latreille MT; Vidal M; Roques B; Garbay C; Ducruix A J Mol Biol; 2002 Feb; 315(5):1167-77. PubMed ID: 11827484 [TBL] [Abstract][Full Text] [Related] [Next] [New Search]