BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

210 related articles for article (PubMed ID: 30884797)

  • 1. Introduction of Nonacidic Side Chains on 6-Ethylcholane Scaffolds in the Identification of Potent Bile Acid Receptor Agonists with Improved Pharmacokinetic Properties.
    Finamore C; Baronissi G; Marchianò S; Di Leva FS; Carino A; Monti MC; Limongelli V; Zampella A; Fiorucci S; Sepe V
    Molecules; 2019 Mar; 24(6):. PubMed ID: 30884797
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Navigation in bile acid chemical space: discovery of novel FXR and GPBAR1 ligands.
    Finamore C; Festa C; Renga B; Sepe V; Carino A; Masullo D; Biagioli M; Marchianò S; Capolupo A; Monti MC; Fiorucci S; Zampella A
    Sci Rep; 2016 Jul; 6():29320. PubMed ID: 27381677
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Design, synthesis, and biological evaluation of potent dual agonists of nuclear and membrane bile acid receptors.
    D'Amore C; Di Leva FS; Sepe V; Renga B; Del Gaudio C; D'Auria MV; Zampella A; Fiorucci S; Limongelli V
    J Med Chem; 2014 Feb; 57(3):937-54. PubMed ID: 24387325
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Investigation on bile acid receptor regulators. Discovery of cholanoic acid derivatives with dual G-protein coupled bile acid receptor 1 (GPBAR1) antagonistic and farnesoid X receptor (FXR) modulatory activity.
    Sepe V; Renga B; Festa C; Finamore C; Masullo D; Carino A; Cipriani S; Distrutti E; Fiorucci S; Zampella A
    Steroids; 2016 Jan; 105():59-67. PubMed ID: 26607331
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Exploitation of cholane scaffold for the discovery of potent and selective farnesoid X receptor (FXR) and G-protein coupled bile acid receptor 1 (GP-BAR1) ligands.
    Festa C; Renga B; D'Amore C; Sepe V; Finamore C; De Marino S; Carino A; Cipriani S; Monti MC; Zampella A; Fiorucci S
    J Med Chem; 2014 Oct; 57(20):8477-95. PubMed ID: 25247751
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Insights on FXR selective modulation. Speculation on bile acid chemical space in the discovery of potent and selective agonists.
    Sepe V; Festa C; Renga B; Carino A; Cipriani S; Finamore C; Masullo D; Del Gaudio F; Monti MC; Fiorucci S; Zampella A
    Sci Rep; 2016 Jan; 6():19008. PubMed ID: 26740187
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Nonacidic Farnesoid X Receptor Modulators.
    Flesch D; Cheung SY; Schmidt J; Gabler M; Heitel P; Kramer J; Kaiser A; Hartmann M; Lindner M; Lüddens-Dämgen K; Heering J; Lamers C; Lüddens H; Wurglics M; Proschak E; Schubert-Zsilavecz M; Merk D
    J Med Chem; 2017 Aug; 60(16):7199-7205. PubMed ID: 28749691
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Steroidal scaffolds as FXR and GPBAR1 ligands: from chemistry to therapeutical application.
    Sepe V; Distrutti E; Limongelli V; Fiorucci S; Zampella A
    Future Med Chem; 2015; 7(9):1109-35. PubMed ID: 26132522
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Chemistry and Pharmacology of GPBAR1 and FXR Selective Agonists, Dual Agonists, and Antagonists.
    De Marino S; Festa C; Sepe V; Zampella A
    Handb Exp Pharmacol; 2019; 256():137-165. PubMed ID: 31201554
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Structure-guided modification of isoxazole-type FXR agonists: Identification of a potent and orally bioavailable FXR modulator.
    Luo G; Lin X; Li Z; Xiao M; Li X; Zhang D; Xiang H
    Eur J Med Chem; 2021 Jan; 209():112910. PubMed ID: 33049605
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Bile acid modulators for the treatment of nonalcoholic steatohepatitis (NASH).
    Fiorucci S; Biagioli M; Sepe V; Zampella A; Distrutti E
    Expert Opin Investig Drugs; 2020 Jun; 29(6):623-632. PubMed ID: 32552182
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Development of bile acid activated receptors hybrid molecules for the treatment of inflammatory and metabolic disorders.
    Fiorucci S; Sepe V; Biagioli M; Fiorillo B; Rapacciuolo P; Distrutti E; Zampella A
    Biochem Pharmacol; 2023 Oct; 216():115776. PubMed ID: 37659739
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Bile acid-activated receptors and the regulation of macrophages function in metabolic disorders.
    Fiorucci S; Baldoni M; Ricci P; Zampella A; Distrutti E; Biagioli M
    Curr Opin Pharmacol; 2020 Aug; 53():45-54. PubMed ID: 32480317
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Structural Insight into the Binding Mode of FXR and GPBAR1 Modulators.
    Di Leva FS; Di Marino D; Limongelli V
    Handb Exp Pharmacol; 2019; 256():111-136. PubMed ID: 31161298
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Farnesoid X receptor: from medicinal chemistry to clinical applications.
    Fiorucci S; Mencarelli A; Distrutti E; Zampella A
    Future Med Chem; 2012 May; 4(7):877-91. PubMed ID: 22571613
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Bile acid receptors and the kidney.
    Herman-Edelstein M; Weinstein T; Levi M
    Curr Opin Nephrol Hypertens; 2018 Jan; 27(1):56-62. PubMed ID: 29045336
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Bile acid receptors in non-alcoholic fatty liver disease.
    Li Y; Jadhav K; Zhang Y
    Biochem Pharmacol; 2013 Dec; 86(11):1517-24. PubMed ID: 23988487
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Progress and challenges of selective Farnesoid X Receptor modulation.
    Massafra V; Pellicciari R; Gioiello A; van Mil SWC
    Pharmacol Ther; 2018 Nov; 191():162-177. PubMed ID: 29933033
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Recent Progress on Bile Acid Receptor Modulators for Treatment of Metabolic Diseases.
    Xu Y
    J Med Chem; 2016 Jul; 59(14):6553-79. PubMed ID: 26878262
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Reversal of metabolic disorders by pharmacological activation of bile acid receptors TGR5 and FXR.
    Jadhav K; Xu Y; Xu Y; Li Y; Xu J; Zhu Y; Adorini L; Lee YK; Kasumov T; Yin L; Zhang Y
    Mol Metab; 2018 Mar; 9():131-140. PubMed ID: 29361497
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.