271 related articles for article (PubMed ID: 30904577)
1. iPSCs-derived nerve-like cells from familial Alzheimer's disease PSEN 1 E280A reveal increased amyloid-beta levels and loss of the Y chromosome.
Mendivil-Perez M; Velez-Pardo C; Kosik KS; Lopera F; Jimenez-Del-Rio M
Neurosci Lett; 2019 Jun; 703():111-118. PubMed ID: 30904577
[TBL] [Abstract][Full Text] [Related]
2. Early pathogenic event of Alzheimer's disease documented in iPSCs from patients with PSEN1 mutations.
Yang J; Zhao H; Ma Y; Shi G; Song J; Tang Y; Li S; Li T; Liu N; Tang F; Gu J; Zhang L; Zhang Z; Zhang X; Jin Y; Le W
Oncotarget; 2017 Jan; 8(5):7900-7913. PubMed ID: 27926491
[TBL] [Abstract][Full Text] [Related]
3. Neurons derived from sporadic Alzheimer's disease iPSCs reveal elevated TAU hyperphosphorylation, increased amyloid levels, and GSK3B activation.
Ochalek A; Mihalik B; Avci HX; Chandrasekaran A; Téglási A; Bock I; Giudice ML; Táncos Z; Molnár K; László L; Nielsen JE; Holst B; Freude K; Hyttel P; Kobolák J; Dinnyés A
Alzheimers Res Ther; 2017 Dec; 9(1):90. PubMed ID: 29191219
[TBL] [Abstract][Full Text] [Related]
4. Characterization and molecular profiling of PSEN1 familial Alzheimer's disease iPSC-derived neural progenitors.
Sproul AA; Jacob S; Pre D; Kim SH; Nestor MW; Navarro-Sobrino M; Santa-Maria I; Zimmer M; Aubry S; Steele JW; Kahler DJ; Dranovsky A; Arancio O; Crary JF; Gandy S; Noggle SA
PLoS One; 2014; 9(1):e84547. PubMed ID: 24416243
[TBL] [Abstract][Full Text] [Related]
5. PSEN1 E280A Cholinergic-like Neurons and Cerebral Spheroids Derived from Mesenchymal Stromal Cells and from Induced Pluripotent Stem Cells Are Neuropathologically Equivalent.
Mendivil-Perez M; Velez-Pardo C; Lopera F; Kosik KS; Jimenez-Del-Rio M
Int J Mol Sci; 2023 May; 24(10):. PubMed ID: 37240306
[TBL] [Abstract][Full Text] [Related]
6. Generation of two isogenic iPSC lines with either a heterozygous or a homozygous E280A mutation in the PSEN1 gene.
Frederiksen HR; Holst B; Mau-Holzmann UA; Freude K; Schmid B
Stem Cell Res; 2019 Mar; 35():101403. PubMed ID: 30769329
[TBL] [Abstract][Full Text] [Related]
7. Generation of one iPSC line (IMEDEAi006-A) from an early-onset familial Alzheimer's Disease (fAD) patient carrying the E280A mutation in the PSEN1 gene.
Vallejo-Diez S; Fleischer A; Martín-Fernández JM; Sánchez-Gilabert A; Castresana M; Aguillón D; Villegas A; Mastronardi CA; Espinosa LG; Arcos-Burgos M; Del Pozo Á; Herrán E; Gainza E; Isaza-Ruget M; Lopera F; Bachiller D
Stem Cell Res; 2019 May; 37():101440. PubMed ID: 31026686
[TBL] [Abstract][Full Text] [Related]
8. Cholinergic-like neurons carrying PSEN1 E280A mutation from familial Alzheimer's disease reveal intraneuronal sAPPβ fragments accumulation, hyperphosphorylation of TAU, oxidative stress, apoptosis and Ca2+ dysregulation: Therapeutic implications.
Soto-Mercado V; Mendivil-Perez M; Velez-Pardo C; Lopera F; Jimenez-Del-Rio M
PLoS One; 2020; 15(5):e0221669. PubMed ID: 32437347
[TBL] [Abstract][Full Text] [Related]
9. A Novel PSEN1 K311R Mutation Discovered in Chinese Families with Late-Onset Alzheimer's Disease Affects Amyloid-β Production and Tau Phosphorylation.
Dong J; Qin W; Wei C; Tang Y; Wang Q; Jia J
J Alzheimers Dis; 2017; 57(2):613-623. PubMed ID: 28269784
[TBL] [Abstract][Full Text] [Related]
10. A Large Panel of Isogenic APP and PSEN1 Mutant Human iPSC Neurons Reveals Shared Endosomal Abnormalities Mediated by APP β-CTFs, Not Aβ.
Kwart D; Gregg A; Scheckel C; Murphy EA; Paquet D; Duffield M; Fak J; Olsen O; Darnell RB; Tessier-Lavigne M
Neuron; 2019 Oct; 104(2):256-270.e5. PubMed ID: 31416668
[TBL] [Abstract][Full Text] [Related]
11. Modeling familial Alzheimer's disease with induced pluripotent stem cells.
Yagi T; Ito D; Okada Y; Akamatsu W; Nihei Y; Yoshizaki T; Yamanaka S; Okano H; Suzuki N
Hum Mol Genet; 2011 Dec; 20(23):4530-9. PubMed ID: 21900357
[TBL] [Abstract][Full Text] [Related]
12. Familial Alzheimer's Disease Mutations in PSEN1 Lead to Premature Human Stem Cell Neurogenesis.
Arber C; Lovejoy C; Harris L; Willumsen N; Alatza A; Casey JM; Lines G; Kerins C; Mueller AK; Zetterberg H; Hardy J; Ryan NS; Fox NC; Lashley T; Wray S
Cell Rep; 2021 Jan; 34(2):108615. PubMed ID: 33440141
[TBL] [Abstract][Full Text] [Related]
13. Calcilytic NPS 2143 Reduces Amyloid Secretion and Increases sAβPPα Release from PSEN1 Mutant iPSC-Derived Neurons.
Lo Giudice M; Mihalik B; Turi Z; Dinnyés A; Kobolák J
J Alzheimers Dis; 2019; 72(3):885-899. PubMed ID: 31640098
[TBL] [Abstract][Full Text] [Related]
14. Increased susceptibility to Aβ toxicity in neuronal cultures derived from familial Alzheimer's disease (PSEN1-A246E) induced pluripotent stem cells.
Armijo E; Gonzalez C; Shahnawaz M; Flores A; Davis B; Soto C
Neurosci Lett; 2017 Feb; 639():74-81. PubMed ID: 28034781
[TBL] [Abstract][Full Text] [Related]
15. Generation of induced pluripotent stem cells (iPSCs) from an Alzheimer's disease patient carrying an A79V mutation in PSEN1.
Li T; Pires C; Nielsen TT; Waldemar G; Hjermind LE; Nielsen JE; Dinnyes A; Hyttel P; Freude KK
Stem Cell Res; 2016 Mar; 16(2):229-32. PubMed ID: 27345973
[TBL] [Abstract][Full Text] [Related]
16. Generation of induced pluripotent stem cells (iPSCs) from an Alzheimer's disease patient carrying a M146I mutation in PSEN1.
Li T; Pires C; Nielsen TT; Waldemar G; Hjermind LE; Nielsen JE; Dinnyes A; Holst B; Hyttel P; Freude KK
Stem Cell Res; 2016 Mar; 16(2):334-7. PubMed ID: 27345998
[TBL] [Abstract][Full Text] [Related]
17. Probing sporadic and familial Alzheimer's disease using induced pluripotent stem cells.
Israel MA; Yuan SH; Bardy C; Reyna SM; Mu Y; Herrera C; Hefferan MP; Van Gorp S; Nazor KL; Boscolo FS; Carson CT; Laurent LC; Marsala M; Gage FH; Remes AM; Koo EH; Goldstein LS
Nature; 2012 Jan; 482(7384):216-20. PubMed ID: 22278060
[TBL] [Abstract][Full Text] [Related]
18. Induced pluripotent stem cells from familial Alzheimer's disease patients differentiate into mature neurons with amyloidogenic properties.
Mahairaki V; Ryu J; Peters A; Chang Q; Li T; Park TS; Burridge PW; Talbot CC; Asnaghi L; Martin LJ; Zambidis ET; Koliatsos VE
Stem Cells Dev; 2014 Dec; 23(24):2996-3010. PubMed ID: 25027006
[TBL] [Abstract][Full Text] [Related]
19. PSEN1 Mutant iPSC-Derived Model Reveals Severe Astrocyte Pathology in Alzheimer's Disease.
Oksanen M; Petersen AJ; Naumenko N; Puttonen K; Lehtonen Š; Gubert Olivé M; Shakirzyanova A; Leskelä S; Sarajärvi T; Viitanen M; Rinne JO; Hiltunen M; Haapasalo A; Giniatullin R; Tavi P; Zhang SC; Kanninen KM; Hämäläinen RH; Koistinaho J
Stem Cell Reports; 2017 Dec; 9(6):1885-1897. PubMed ID: 29153989
[TBL] [Abstract][Full Text] [Related]
20. Generation of induced pluripotent stem cells (iPSCs) from an Alzheimer's disease patient carrying a L150P mutation in PSEN-1.
Tubsuwan A; Pires C; Rasmussen MA; Schmid B; Nielsen JE; Hjermind LE; Hall V; Nielsen TT; Waldemar G; Hyttel P; Clausen C; Kitiyanant N; Freude KK; Holst B
Stem Cell Res; 2016 Jan; 16(1):110-2. PubMed ID: 27345792
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
