BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

253 related articles for article (PubMed ID: 30904971)

  • 41. Design and discovery of thioether and nicotinamide containing sorafenib analogues as multikinase inhibitors targeting B-Raf, B-Raf
    Sun S; He Z; Huang M; Wang N; He Z; Kong X; Yao J
    Bioorg Med Chem; 2018 May; 26(9):2381-2391. PubMed ID: 29631788
    [TBL] [Abstract][Full Text] [Related]  

  • 42. Design, synthesis and biological evaluation of pyrimidine-based derivatives as VEGFR-2 tyrosine kinase inhibitors.
    Sun W; Hu S; Fang S; Yan H
    Bioorg Chem; 2018 Aug; 78():393-405. PubMed ID: 29677483
    [TBL] [Abstract][Full Text] [Related]  

  • 43. Discovery of biphenyl-aryl ureas as novel VEGFR-2 inhibitors. Part 4: exploration of diverse hinge-binding fragments.
    Su P; Wang J; Shi Y; Pan X; Shao R; Zhang J
    Bioorg Med Chem; 2015 Jul; 23(13):3228-36. PubMed ID: 25982075
    [TBL] [Abstract][Full Text] [Related]  

  • 44. Identification of novel PI3Kδ inhibitors by docking, ADMET prediction and molecular dynamics simulations.
    Liu YY; Feng XY; Jia WQ; Jing Z; Xu WR; Cheng XC
    Comput Biol Chem; 2019 Feb; 78():190-204. PubMed ID: 30557817
    [TBL] [Abstract][Full Text] [Related]  

  • 45. Quinoxalinone (Part II). Discovery of (Z)-3-(2-(pyridin-4-yl)vinyl)quinoxalinone derivates as potent VEGFR-2 kinase inhibitors.
    Shi L; Zhou J; Wu J; Cao J; Shen Y; Zhou H; Li X
    Bioorg Med Chem; 2016 Apr; 24(8):1840-52. PubMed ID: 26968648
    [TBL] [Abstract][Full Text] [Related]  

  • 46. Exploration of structural requirements for the inhibition of VEGFR-2 tyrosine kinase: Binding site analysis of type II, 'DFG-out' inhibitors.
    Modi SJ; Kulkarni VM
    J Biomol Struct Dyn; 2022 Aug; 40(12):5712-5727. PubMed ID: 33459187
    [TBL] [Abstract][Full Text] [Related]  

  • 47. Discovery of potent vascular endothelial growth factor receptor-2 inhibitors.
    Papakyriakou A; Katsarou ME; Belimezi M; Karpusas M; Vourloumis D
    ChemMedChem; 2010 Jan; 5(1):118-29. PubMed ID: 19921722
    [TBL] [Abstract][Full Text] [Related]  

  • 48. In silico insights into design of novel VEGFR-2 inhibitors: SMILES-based QSAR modelling, and docking studies on substituted benzo-fused heteronuclear derivatives.
    Gupta S; Kashyap M; Bansal Y; Bansal G
    SAR QSAR Environ Res; 2024 Apr; 35(4):265-284. PubMed ID: 38591137
    [TBL] [Abstract][Full Text] [Related]  

  • 49. Novel multitarget inhibitors with antiangiogenic and immunomodulator properties.
    Conesa-Milián L; Falomir E; Murga J; Carda M; Marco JA
    Eur J Med Chem; 2019 May; 170():87-98. PubMed ID: 30878834
    [TBL] [Abstract][Full Text] [Related]  

  • 50. 2-((1H-Azol-1-yl)methyl)-N-arylbenzamides: novel dual inhibitors of VEGFR-1/2 kinases.
    Kiselyov AS; Semenova M; Semenov VV; Piatnitski E
    Bioorg Med Chem Lett; 2006 Mar; 16(6):1726-30. PubMed ID: 16364640
    [TBL] [Abstract][Full Text] [Related]  

  • 51. Discovery of 8-Amino-Substituted 2-Phenyl-2,7-Naphthyridinone Derivatives as New c-Kit/VEGFR-2 Kinase Inhibitors.
    Sun H; Zhuo L; Dong H; Huang W; She N
    Molecules; 2019 Dec; 24(24):. PubMed ID: 31817456
    [TBL] [Abstract][Full Text] [Related]  

  • 52. Identification of new pyrrolo[2,3-d]pyrimidines as potent VEGFR-2 tyrosine kinase inhibitors: Design, synthesis, biological evaluation and molecular modeling.
    Adel M; Serya RAT; Lasheen DS; Abouzid KAM
    Bioorg Chem; 2018 Dec; 81():612-629. PubMed ID: 30248512
    [TBL] [Abstract][Full Text] [Related]  

  • 53. Structure-Based Drug Design Studies Toward the Discovery of Novel Chalcone Derivatives as Potential Epidermal Growth Factor Receptor (EGFR) Inhibitors.
    Al-Anazi M; Al-Najjar BO; Khairuddean M
    Molecules; 2018 Dec; 23(12):. PubMed ID: 30563058
    [TBL] [Abstract][Full Text] [Related]  

  • 54. Design, synthesis, in silico and antiproliferative evaluation of novel pyrazole derivatives as VEGFR-2 inhibitors.
    Ravula P; Vamaraju HB; Paturi M; Sharath Chandra JNGN
    Arch Pharm (Weinheim); 2018 Jan; 351(1):. PubMed ID: 29205467
    [TBL] [Abstract][Full Text] [Related]  

  • 55. Identification of non-resistant ROS-1 inhibitors using structure based pharmacophore analysis.
    Pathak D; Chadha N; Silakari O
    J Mol Graph Model; 2016 Nov; 70():85-93. PubMed ID: 27693947
    [TBL] [Abstract][Full Text] [Related]  

  • 56. Quantitative structure activity relationship and molecular simulations for the exploration of natural potent VEGFR-2 inhibitors: an
    Sharma N; Sharma M; Rahman QI; Akhtar S; Muddassir M
    J Biomol Struct Dyn; 2021 May; 39(8):2806-2823. PubMed ID: 32363995
    [TBL] [Abstract][Full Text] [Related]  

  • 57. Virtual Screening, Docking, and Designing of New VEGF Inhibitors as Anti-cancer Agents.
    Patel S; Singh VR; Suman AK; Jain S; Sen AK
    Curr Drug Discov Technol; 2024; 21(1):e101023222024. PubMed ID: 38629172
    [TBL] [Abstract][Full Text] [Related]  

  • 58. Identification of novel tyrosine kinase inhibitors for drug resistant T315I mutant BCR-ABL: a virtual screening and molecular dynamics simulations study.
    Banavath HN; Sharma OP; Kumar MS; Baskaran R
    Sci Rep; 2014 Nov; 4():6948. PubMed ID: 25382104
    [TBL] [Abstract][Full Text] [Related]  

  • 59. Increasing the binding affinity of VEGFR-2 inhibitors by extending their hydrophobic interaction with the active site: Design, synthesis and biological evaluation of 1-substituted-4-(4-methoxybenzyl)phthalazine derivatives.
    Eldehna WM; Abou-Seri SM; El Kerdawy AM; Ayyad RR; Hamdy AM; Ghabbour HA; Ali MM; Abou El Ella DA
    Eur J Med Chem; 2016 May; 113():50-62. PubMed ID: 26922228
    [TBL] [Abstract][Full Text] [Related]  

  • 60. Shape-based virtual screening, docking, and molecular dynamics simulations to identify Mtb-ASADH inhibitors.
    Kumar R; Garg P; Bharatam PV
    J Biomol Struct Dyn; 2015; 33(5):1082-93. PubMed ID: 24875451
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 13.