114 related articles for article (PubMed ID: 30910474)
1. Polymorphs, co-crystal structure and pharmacodynamics study of MBRI-001, a deuterium-substituted plinabulin derivative as a tubulin polymerization inhibitor.
Ma M; Ding Z; Wang S; Ma L; Wang Y; Zhong L; Li Z; Yang J; Li W
Bioorg Med Chem; 2019 May; 27(9):1836-1844. PubMed ID: 30910474
[TBL] [Abstract][Full Text] [Related]
2. In vitro and in vivo pharmacokinetic and pharmacodynamic study of MBRI-001, a deuterium-substituted plinabulin derivative as a potent anti-cancer agent.
Ma M; Zhao J; Cheng H; Deng M; Ding Z; Hou Y; Li F; Dou G; Li W
Bioorg Med Chem; 2018 Sep; 26(16):4687-4692. PubMed ID: 30119994
[TBL] [Abstract][Full Text] [Related]
3. Development of MBRI-001, a deuterium-substituted plinabulin derivative as a potent anti-cancer agent.
Ding Z; Cheng H; Wang S; Hou Y; Zhao J; Guan H; Li W
Bioorg Med Chem Lett; 2017 Mar; 27(6):1416-1419. PubMed ID: 28228362
[TBL] [Abstract][Full Text] [Related]
4. Design, synthesis and biological evaluation of anti-pancreatic cancer activity of plinabulin derivatives based on the co-crystal structure.
Fu Z; Hou Y; Ji C; Ma M; Tian Z; Deng M; Zhong L; Chu Y; Li W
Bioorg Med Chem; 2018 May; 26(8):2061-2072. PubMed ID: 29571653
[TBL] [Abstract][Full Text] [Related]
5. Antitumor activity of the microtubule inhibitor MBRI-001 against human hepatocellular carcinoma as monotherapy or in combination with sorafenib.
Deng M; Li L; Zhao J; Yuan S; Li W
Cancer Chemother Pharmacol; 2018 May; 81(5):853-862. PubMed ID: 29532153
[TBL] [Abstract][Full Text] [Related]
6. Development of novel phenoxy-diketopiperazine-type plinabulin derivatives as potent antimicrotubule agents based on the co-crystal structure.
Ding Z; Ma M; Zhong C; Wang S; Fu Z; Hou Y; Liu Y; Zhong L; Chu Y; Li F; Song C; Wang Y; Yang J; Li W
Bioorg Med Chem; 2020 Jan; 28(1):115186. PubMed ID: 31759826
[TBL] [Abstract][Full Text] [Related]
7. Design, synthesis and biological evaluation of a novel tubulin inhibitor 7a3 targeting the colchicine binding site.
Lai Q; Wang Y; Wang R; Lai W; Tang L; Tao Y; Liu Y; Zhang R; Huang L; Xiang H; Zeng S; Gou L; Chen H; Yao Y; Yang J
Eur J Med Chem; 2018 Aug; 156():162-179. PubMed ID: 30006162
[TBL] [Abstract][Full Text] [Related]
8. Structures of a diverse set of colchicine binding site inhibitors in complex with tubulin provide a rationale for drug discovery.
Wang Y; Zhang H; Gigant B; Yu Y; Wu Y; Chen X; Lai Q; Yang Z; Chen Q; Yang J
FEBS J; 2016 Jan; 283(1):102-11. PubMed ID: 26462166
[TBL] [Abstract][Full Text] [Related]
9. Synthesis of deuterium-enriched and fluorine-substituted plinabulin derivatives and evaluation of their antitumor activities.
Ding Z; Hou Y; Wang S; Sun T; Ma M; Guan H; Li W
Mol Divers; 2017 Aug; 21(3):577-583. PubMed ID: 28488201
[TBL] [Abstract][Full Text] [Related]
10. Design, synthesis and anti-tumor evaluation of plinabulin derivatives as potential agents targeting β-tubulin.
Fang S; Bi S; Li Y; Tian S; Xu H; Fu L; Wang S; Tang Y; Qiu P
Bioorg Med Chem Lett; 2023 Jul; 91():129370. PubMed ID: 37301522
[TBL] [Abstract][Full Text] [Related]
11. Medicinal chemistry and chemical biology of diketopiperazine-type antimicrotubule and vascular-disrupting agents.
Hayashi Y; Yamazaki-Nakamura Y; Yakushiji F
Chem Pharm Bull (Tokyo); 2013; 61(9):889-901. PubMed ID: 23995353
[TBL] [Abstract][Full Text] [Related]
12. Platinum(IV) complexes conjugated with phenstatin analogue as inhibitors of microtubule polymerization and reverser of multidrug resistance.
Huang X; Huang R; Gou S; Wang Z; Liao Z; Wang H
Bioorg Med Chem; 2017 Sep; 25(17):4686-4700. PubMed ID: 28728896
[TBL] [Abstract][Full Text] [Related]
13. Design, synthesis, biological evaluation and cocrystal structures with tubulin of chiral β-lactam bridged combretastatin A-4 analogues as potent antitumor agents.
Zhou P; Liang Y; Zhang H; Jiang H; Feng K; Xu P; Wang J; Wang X; Ding K; Luo C; Liu M; Wang Y
Eur J Med Chem; 2018 Jan; 144():817-842. PubMed ID: 29306206
[TBL] [Abstract][Full Text] [Related]
14. 1-Phenyl-dihydrobenzoindazoles as novel colchicine site inhibitors: Structural basis and antitumor efficacy.
Jiang J; Zhang H; Wang C; Zhang Q; Fang S; Zhou R; Hu J; Zhu J; Zhou Y; Luo C; Zheng C
Eur J Med Chem; 2019 Sep; 177():448-456. PubMed ID: 31174062
[TBL] [Abstract][Full Text] [Related]
15. Synthesis and structure-activity relationship study of antimicrotubule agents phenylahistin derivatives with a didehydropiperazine-2,5-dione structure.
Yamazaki Y; Tanaka K; Nicholson B; Deyanat-Yazdi G; Potts B; Yoshida T; Oda A; Kitagawa T; Orikasa S; Kiso Y; Yasui H; Akamatsu M; Chinen T; Usui T; Shinozaki Y; Yakushiji F; Miller BR; Neuteboom S; Palladino M; Kanoh K; Lloyd GK; Hayashi Y
J Med Chem; 2012 Feb; 55(3):1056-71. PubMed ID: 22185476
[TBL] [Abstract][Full Text] [Related]
16. A novel synthetic compound exerts effective anti-tumour activity in vivo via the inhibition of tubulin polymerisation in A549 cells.
Yan J; Pang Y; Sheng J; Wang Y; Chen J; Hu J; Huang L; Li X
Biochem Pharmacol; 2015 Sep; 97(1):51-61. PubMed ID: 26212540
[TBL] [Abstract][Full Text] [Related]
17. A novel bis-indole destabilizes microtubules and displays potent in vitro and in vivo antitumor activity in prostate cancer.
Ahn S; Hwang DJ; Barrett CM; Yang J; Duke CB; Miller DD; Dalton JT
Cancer Chemother Pharmacol; 2011 Feb; 67(2):293-304. PubMed ID: 20383708
[TBL] [Abstract][Full Text] [Related]
18. Design, synthesis and molecular modeling of new 4-phenylcoumarin derivatives as tubulin polymerization inhibitors targeting MCF-7 breast cancer cells.
Batran RZ; Kassem AF; Abbas EMH; Elseginy SA; Mounier MM
Bioorg Med Chem; 2018 Jul; 26(12):3474-3490. PubMed ID: 29793751
[TBL] [Abstract][Full Text] [Related]
19. Design, synthesis, and biological evaluation of novel benzodiazepine derivatives as anticancer agents through inhibition of tubulin polymerization in vitro and in vivo.
Pang Y; Lin H; Ou C; Cao Y; An B; Yan J; Li X
Eur J Med Chem; 2019 Nov; 182():111670. PubMed ID: 31499359
[TBL] [Abstract][Full Text] [Related]
20. Integrating docking and molecular dynamics approaches for a series of proline-based 2,5-diketopiperazines as novel αβ-tubulin inhibitors.
Fani N; Bordbar AK; Ghayeb Y; Sepehri S
J Biomol Struct Dyn; 2015; 33(10):2285-95. PubMed ID: 25616934
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
