These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
5. Biochemical characterization of pathogenic mutations in human mitochondrial methionyl-tRNA formyltransferase. Sinha A; Köhrer C; Weber MH; Masuda I; Mootha VK; Hou YM; RajBhandary UL J Biol Chem; 2014 Nov; 289(47):32729-41. PubMed ID: 25288793 [TBL] [Abstract][Full Text] [Related]
6. Identification and functional characterization of a novel MTFMT mutation associated with selective vulnerability of the visual pathway and a mild neurological phenotype. La Piana R; Weraarpachai W; Ospina LH; Tetreault M; Majewski J; ; Bruce Pike G; Decarie JC; Tampieri D; Brais B; Shoubridge EA Neurogenetics; 2017 Apr; 18(2):97-103. PubMed ID: 28058511 [TBL] [Abstract][Full Text] [Related]
7. Multisystem mitochondrial diseases due to mutations in mtDNA-encoded subunits of complex I. Danhelovska T; Kolarova H; Zeman J; Hansikova H; Vaneckova M; Lambert L; Kucerova-Vidrova V; Berankova K; Honzik T; Tesarova M BMC Pediatr; 2020 Jan; 20(1):41. PubMed ID: 31996177 [TBL] [Abstract][Full Text] [Related]
9. Autonomic instability, arrhythmia and visual impairment in a new presentation of Howard C; Dev-Borman A; Stokes J; O'Rourke D; Gillespie C; Twomey E; Knerr I; Boruah R JIMD Rep; 2023 Mar; 64(2):150-155. PubMed ID: 36873085 [TBL] [Abstract][Full Text] [Related]
10. Leigh syndrome followed by parkinsonism in an adult with homozygous c.626C>T mutation in Hemelsoet DM; Vanlander AV; Smet J; Vantroys E; Acou M; Goethals I; Sante T; Seneca S; Menten B; Van Coster R Neurol Genet; 2018 Dec; 4(6):e298. PubMed ID: 30569017 [TBL] [Abstract][Full Text] [Related]
11. Clinical and laboratory survey of 65 Chinese patients with Leigh syndrome. Yang YL; Sun F; Zhang Y; Qian N; Yuan Y; Wang ZX; Qi Y; Xiao JX; Wang XY; Qi ZY; Zhang YH; Jiang YW; Bao XH; Qin J; Wu XR Chin Med J (Engl); 2006 Mar; 119(5):373-7. PubMed ID: 16542579 [TBL] [Abstract][Full Text] [Related]
12. Genetic heterogeneity in Leigh syndrome: Highlighting treatable and novel genetic causes. Lee JS; Yoo T; Lee M; Lee Y; Jeon E; Kim SY; Lim BC; Kim KJ; Choi M; Chae JH Clin Genet; 2020 Apr; 97(4):586-594. PubMed ID: 32020600 [TBL] [Abstract][Full Text] [Related]
13. Pathogenic Bi-allelic Mutations in NDUFAF8 Cause Leigh Syndrome with an Isolated Complex I Deficiency. Alston CL; Veling MT; Heidler J; Taylor LS; Alaimo JT; Sung AY; He L; Hopton S; Broomfield A; Pavaine J; Diaz J; Leon E; Wolf P; McFarland R; Prokisch H; Wortmann SB; Bonnen PE; Wittig I; Pagliarini DJ; Taylor RW Am J Hum Genet; 2020 Jan; 106(1):92-101. PubMed ID: 31866046 [TBL] [Abstract][Full Text] [Related]
14. [Clinical and genetic characteristics of children with Leigh syndrome]. Fang F; Shen Y; Shen DM; Liu ZM; Ding CH; Zhang WC; Sun SZ; Lyu JL; Han TL; Wang XH; Zhang WH; Yang XY; Li JW; Wu HS Zhonghua Er Ke Za Zhi; 2017 Mar; 55(3):205-209. PubMed ID: 28273704 [No Abstract] [Full Text] [Related]
15. MtDNA mutations are a common cause of severe disease phenotypes in children with Leigh syndrome. Naess K; Freyer C; Bruhn H; Wibom R; Malm G; Nennesmo I; von Döbeln U; Larsson NG Biochim Biophys Acta; 2009 May; 1787(5):484-90. PubMed ID: 19103152 [TBL] [Abstract][Full Text] [Related]
16. Biallelic Mutations in MRPS34 Lead to Instability of the Small Mitoribosomal Subunit and Leigh Syndrome. Lake NJ; Webb BD; Stroud DA; Richman TR; Ruzzenente B; Compton AG; Mountford HS; Pulman J; Zangarelli C; Rio M; Boddaert N; Assouline Z; Sherpa MD; Schadt EE; Houten SM; Byrnes J; McCormick EM; Zolkipli-Cunningham Z; Haude K; Zhang Z; Retterer K; Bai R; Calvo SE; Mootha VK; Christodoulou J; Rötig A; Filipovska A; Cristian I; Falk MJ; Metodiev MD; Thorburn DR Am J Hum Genet; 2017 Aug; 101(2):239-254. PubMed ID: 28777931 [TBL] [Abstract][Full Text] [Related]
17. An N-terminal formyl methionine on COX 1 is required for the assembly of cytochrome c oxidase. Hinttala R; Sasarman F; Nishimura T; Antonicka H; Brunel-Guitton C; Schwartzentruber J; Fahiminiya S; Majewski J; Faubert D; Ostergaard E; Smeitink JA; Shoubridge EA Hum Mol Genet; 2015 Jul; 24(14):4103-13. PubMed ID: 25911677 [TBL] [Abstract][Full Text] [Related]
18. Novel mutations in the mitochondrial complex I assembly gene NDUFAF5 reveal heterogeneous phenotypes. Simon MT; Eftekharian SS; Stover AE; Osborne AF; Braffman BH; Chang RC; Wang RY; Steenari MR; Tang S; Hwu PW; Taft RJ; Benke PJ; Abdenur JE Mol Genet Metab; 2019 Jan; 126(1):53-63. PubMed ID: 30473481 [TBL] [Abstract][Full Text] [Related]
19. Leigh syndrome associated with mitochondrial complex I deficiency due to novel mutations In NDUFV1 and NDUFS2. Marin SE; Mesterman R; Robinson B; Rodenburg RJ; Smeitink J; Tarnopolsky MA Gene; 2013 Mar; 516(1):162-7. PubMed ID: 23266820 [TBL] [Abstract][Full Text] [Related]
20. Clinical and magnetic resonance imaging findings in patients with Leigh syndrome and SURF1 mutations. Sonam K; Khan NA; Bindu PS; Taly AB; Gayathri N; Bharath MM; Govindaraju C; Arvinda HR; Nagappa M; Sinha S; Thangaraj K Brain Dev; 2014 Oct; 36(9):807-12. PubMed ID: 24262866 [TBL] [Abstract][Full Text] [Related] [Next] [New Search]