BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

230 related articles for article (PubMed ID: 30913963)

  • 1. Development of a high-throughput solubility screening assay for use in antibody discovery.
    Chai Q; Shih J; Weldon C; Phan S; Jones BE
    MAbs; 2019; 11(4):747-756. PubMed ID: 30913963
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Application of a high-throughput screening procedure with PEG-induced precipitation to compare relative protein solubility during formulation development with IgG1 monoclonal antibodies.
    Gibson TJ; Mccarty K; Mcfadyen IJ; Cash E; Dalmonte P; Hinds KD; Dinerman AA; Alvarez JC; Volkin DB
    J Pharm Sci; 2011 Mar; 100(3):1009-21. PubMed ID: 21280052
    [TBL] [Abstract][Full Text] [Related]  

  • 3. A Micro-Polyethylene Glycol Precipitation Assay as a Relative Solubility Screening Tool for Monoclonal Antibody Design and Formulation Development.
    Toprani VM; Joshi SB; Kueltzo LA; Schwartz RM; Middaugh CR; Volkin DB
    J Pharm Sci; 2016 Aug; 105(8):2319-27. PubMed ID: 27368120
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Predicting Colloidal Stability of High-Concentration Monoclonal Antibody Formulations in Common Pharmaceutical Buffers Using Improved Polyethylene Glycol Induced Protein Precipitation Assay.
    Meza NP; Hardy CA; Morin KH; Huang C; Raghava S; Song J; Zhang J; Wang Y
    Mol Pharm; 2023 Nov; 20(11):5842-5855. PubMed ID: 37867303
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Application of a PEG precipitation method for solubility screening: a tool for developing high protein concentration formulations.
    Li L; Kantor A; Warne N
    Protein Sci; 2013 Aug; 22(8):1118-23. PubMed ID: 23740802
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Limitations of polyethylene glycol-induced precipitation as predictive tool for protein solubility during formulation development.
    Hofmann M; Winzer M; Weber C; Gieseler H
    J Pharm Pharmacol; 2018 May; 70(5):648-654. PubMed ID: 28106257
    [TBL] [Abstract][Full Text] [Related]  

  • 7. High-throughput screening techniques for rapid PEG-based precipitation of IgG4 mAb from clarified cell culture supernatant.
    Knevelman C; Davies J; Allen L; Titchener-Hooker NJ
    Biotechnol Prog; 2010; 26(3):697-705. PubMed ID: 20014099
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Matching pH values for antibody stabilization and crystallization suggest rationale for accelerated development of biotherapeutic drugs.
    Sjuts H; Schreuder H; Engel CK; Bussemer T; Gokarn Y
    Drug Dev Res; 2020 May; 81(3):329-337. PubMed ID: 31758731
    [TBL] [Abstract][Full Text] [Related]  

  • 9. High throughput solubility and redissolution screening for antibody purification via combined PEG and zinc chloride precipitation.
    Gu Q; Li Z; Coffman JL; Przybycien TM; Zydney AL
    Biotechnol Prog; 2020 Nov; 36(6):e3041. PubMed ID: 32583625
    [TBL] [Abstract][Full Text] [Related]  

  • 10. An alternative assay to hydrophobic interaction chromatography for high-throughput characterization of monoclonal antibodies.
    Estep P; Caffry I; Yu Y; Sun T; Cao Y; Lynaugh H; Jain T; Vásquez M; Tessier PM; Xu Y
    MAbs; 2015; 7(3):553-61. PubMed ID: 25790175
    [TBL] [Abstract][Full Text] [Related]  

  • 11. AF4 and PEG Precipitation as Predictive Assays for Antibody Self-Association.
    Condado-Morales I; Sokolova V; Wahlund PO; Heding KE; Auclair S; Kingsbury JS; Arosio P; Lorenzen N
    Mol Pharm; 2023 Feb; 20(2):1323-1330. PubMed ID: 36668814
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Ultradilute Measurements of Self-Association for the Identification of Antibodies with Favorable High-Concentration Solution Properties.
    Starr CG; Makowski EK; Wu L; Berg B; Kingsbury JS; Gokarn YR; Tessier PM
    Mol Pharm; 2021 Jul; 18(7):2744-2753. PubMed ID: 34105965
    [TBL] [Abstract][Full Text] [Related]  

  • 13. High-throughput screening for developability during early-stage antibody discovery using self-interaction nanoparticle spectroscopy.
    Liu Y; Caffry I; Wu J; Geng SB; Jain T; Sun T; Reid F; Cao Y; Estep P; Yu Y; Vásquez M; Tessier PM; Xu Y
    MAbs; 2014; 6(2):483-92. PubMed ID: 24492294
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Development of QSAR models for
    Han X; Shih J; Lin Y; Chai Q; Cramer SM
    MAbs; 2022; 14(1):2062807. PubMed ID: 35442164
    [TBL] [Abstract][Full Text] [Related]  

  • 15. High-throughput assay for measuring monoclonal antibody self-association and aggregation in serum.
    Li X; Geng SB; Chiu ML; Saro D; Tessier PM
    Bioconjug Chem; 2015 Mar; 26(3):520-8. PubMed ID: 25714504
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Revisit PEG-Induced Precipitation Assay for Protein Solubility Assessment of Monoclonal Antibody Formulations.
    Scannell MJ; Hyatt MW; Budyak IL; Woldeyes MA; Wang Y
    Pharm Res; 2021 Nov; 38(11):1947-1960. PubMed ID: 34647231
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Relationship of PEG-induced precipitation with protein-protein interactions and aggregation rates of high concentration mAb formulations at 5 °C.
    Wälchli R; Fanizzi F; Massant J; Arosio P
    Eur J Pharm Biopharm; 2020 Jun; 151():53-60. PubMed ID: 32197816
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Biophysical and Sequence-Based Methods for Identifying Monovalent and Bivalent Antibodies with High Colloidal Stability.
    Alam ME; Geng SB; Bender C; Ludwig SD; Linden L; Hoet R; Tessier PM
    Mol Pharm; 2018 Jan; 15(1):150-163. PubMed ID: 29154550
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Discovery of highly soluble antibodies prior to purification using affinity-capture self-interaction nanoparticle spectroscopy.
    Wu J; Schultz JS; Weldon CL; Sule SV; Chai Q; Geng SB; Dickinson CD; Tessier PM
    Protein Eng Des Sel; 2015 Oct; 28(10):403-14. PubMed ID: 26363633
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Developability Assessment of Engineered Monoclonal Antibody Variants with a Complex Self-Association Behavior Using Complementary Analytical and in Silico Tools.
    Shan L; Mody N; Sormani P; Rosenthal KL; Damschroder MM; Esfandiary R
    Mol Pharm; 2018 Dec; 15(12):5697-5710. PubMed ID: 30395473
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 12.