These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
92 related articles for article (PubMed ID: 30918925)
1. Computational modeling of the catalytic mechanism of hydroxymethylbilane synthase. Bung N; Roy A; Priyakumar UD; Bulusu G Phys Chem Chem Phys; 2019 Apr; 21(15):7932-7940. PubMed ID: 30918925 [TBL] [Abstract][Full Text] [Related]
2. Crystal structures of hydroxymethylbilane synthase complexed with a substrate analog: a single substrate-binding site for four consecutive condensation steps. Sato H; Sugishima M; Tsukaguchi M; Masuko T; Iijima M; Takano M; Omata Y; Hirabayashi K; Wada K; Hisaeda Y; Yamamoto K Biochem J; 2021 Mar; 478(5):1023-1042. PubMed ID: 33600566 [TBL] [Abstract][Full Text] [Related]
3. Human hydroxymethylbilane synthase: Molecular dynamics of the pyrrole chain elongation identifies step-specific residues that cause AIP. Bung N; Roy A; Chen B; Das D; Pradhan M; Yasuda M; New MI; Desnick RJ; Bulusu G Proc Natl Acad Sci U S A; 2018 Apr; 115(17):E4071-E4080. PubMed ID: 29632172 [TBL] [Abstract][Full Text] [Related]
4. One ring closer to a closure: the crystal structure of the ES Bustad HJ; Christie MS; Laitaoja M; Aarsand AK; Martinez A; Jänis J; Kallio JP FEBS J; 2024 Feb; 291(3):510-526. PubMed ID: 37863644 [TBL] [Abstract][Full Text] [Related]
5. Structural insights into E. coli porphobilinogen deaminase during synthesis and exit of 1-hydroxymethylbilane. Bung N; Pradhan M; Srinivasan H; Bulusu G PLoS Comput Biol; 2014 Mar; 10(3):e1003484. PubMed ID: 24603363 [TBL] [Abstract][Full Text] [Related]
7. Conformational stability and activity analysis of two hydroxymethylbilane synthase mutants, K132N and V215E, with different phenotypic association with acute intermittent porphyria. Bustad HJ; Vorland M; Rønneseth E; Sandberg S; Martinez A; Toska K Biosci Rep; 2013 Aug; 33(4):. PubMed ID: 23815679 [TBL] [Abstract][Full Text] [Related]
8. Time-resolved and static-ensemble structural chemistry of hydroxymethylbilane synthase. Helliwell JR; Nieh YP; Habash J; Faulder PF; Raftery J; Cianci M; Wulff M; Hädener A Faraday Discuss; 2003; 122():131-44; discussion 171-90. PubMed ID: 12555854 [TBL] [Abstract][Full Text] [Related]
9. Insights into the mechanism of pyrrole polymerization catalysed by porphobilinogen deaminase: high-resolution X-ray studies of the Arabidopsis thaliana enzyme. Roberts A; Gill R; Hussey RJ; Mikolajek H; Erskine PT; Cooper JB; Wood SP; Chrystal EJ; Shoolingin-Jordan PM Acta Crystallogr D Biol Crystallogr; 2013 Mar; 69(Pt 3):471-85. PubMed ID: 23519422 [TBL] [Abstract][Full Text] [Related]
10. Network analysis of hydroxymethylbilane synthase dynamics. Chakrabarty B; Das D; Bung N; Roy A; Bulusu G J Mol Graph Model; 2020 Sep; 99():107641. PubMed ID: 32619952 [TBL] [Abstract][Full Text] [Related]
11. Structural studies of domain movement in active-site mutants of porphobilinogen deaminase from Bacillus megaterium. Guo J; Erskine P; Coker AR; Wood SP; Cooper JB Acta Crystallogr F Struct Biol Commun; 2017 Nov; 73(Pt 11):612-620. PubMed ID: 29095155 [TBL] [Abstract][Full Text] [Related]
12. Structural basis of pyrrole polymerization in human porphobilinogen deaminase. Pluta P; Roversi P; Bernardo-Seisdedos G; Rojas AL; Cooper JB; Gu S; Pickersgill RW; Millet O Biochim Biophys Acta Gen Subj; 2018 Sep; 1862(9):1948-1955. PubMed ID: 29908816 [TBL] [Abstract][Full Text] [Related]
13. Investigation into the nature of substrate binding to the dipyrromethane cofactor of Escherichia coli porphobilinogen deaminase. Warren MJ; Jordan PM Biochemistry; 1988 Dec; 27(25):9020-30. PubMed ID: 3069132 [TBL] [Abstract][Full Text] [Related]
14. Characterisation of a common hotspot variant in acute intermittent porphyria sheds light on the mechanism of hydroxymethylbilane synthase function. Christie MS; Laitaoja M; Aarsand AK; Kallio JP; Bustad HJ FEBS Open Bio; 2022 Dec; 12(12):2136-2146. PubMed ID: 36115019 [TBL] [Abstract][Full Text] [Related]
15. Purification, characterization, crystallisation and X-ray analysis of selenomethionine-labelled hydroxymethylbilane synthase from Escherichia coli. Hädener A; Matzinger PK; Malashkevich VN; Louie GV; Wood SP; Oliver P; Alefounder PR; Pitt AR; Abell C; Battersby AR Eur J Biochem; 1993 Feb; 211(3):615-24. PubMed ID: 8436121 [TBL] [Abstract][Full Text] [Related]
16. Determination of the structure of seleno-methionine-labelled hydroxymethylbilane synthase in its active form by multi-wavelength anomalous dispersion. Hädener A; Matzinger PK; Battersby AR; McSweeney S; Thompson AW; Hammersley AP; Harrop SJ; Cassetta A; Deacon A; Hunter WN; Nieh YP; Raftery J; Hunter N; Helliwell JR Acta Crystallogr D Biol Crystallogr; 1999 Mar; 55(Pt 3):631-43. PubMed ID: 10089459 [TBL] [Abstract][Full Text] [Related]
17. Site-directed mutagenesis and high-resolution NMR spectroscopy of the active site of porphobilinogen deaminase. Scott AI; Roessner CA; Stolowich NJ; Karuso P; Williams HJ; Grant SK; Gonzalez MD; Hoshino T Biochemistry; 1988 Oct; 27(21):7984-90. PubMed ID: 3069124 [TBL] [Abstract][Full Text] [Related]
18. Yeast porphobilinogen deaminase also forms enzyme-pyrrole intermediates. Correa Garcia S; Rossetti MV; Bermudez Moretti M; Batlle AM Enzyme Protein; 1994-1995; 48(5-6):275-81. PubMed ID: 8792872 [TBL] [Abstract][Full Text] [Related]
19. The crystal structures of the enzyme hydroxymethylbilane synthase, also known as porphobilinogen deaminase. Helliwell JR Acta Crystallogr F Struct Biol Commun; 2021 Nov; 77(Pt 11):388-398. PubMed ID: 34726177 [TBL] [Abstract][Full Text] [Related]
20. Heme Binding to Porphobilinogen Deaminase from Vibrio cholerae Decelerates the Formation of 1-Hydroxymethylbilane. Uchida T; Funamizu T; Chen M; Tanaka Y; Ishimori K ACS Chem Biol; 2018 Mar; 13(3):750-760. PubMed ID: 29360345 [TBL] [Abstract][Full Text] [Related] [Next] [New Search]