BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

153 related articles for article (PubMed ID: 30923665)

  • 1. Structural and functional properties of Grb2 SH2 dimer in CD28 binding.
    Hosoe Y; Numoto N; Inaba S; Ogawa S; Morii H; Abe R; Ito N; Oda M
    Biophys Physicobiol; 2019; 16():80-88. PubMed ID: 30923665
    [TBL] [Abstract][Full Text] [Related]  

  • 2. GRB2 dimerization mediated by SH2 domain-swapping is critical for T cell signaling and cytokine production.
    Sandouk A; Xu Z; Baruah S; Tremblay M; Hopkins JB; Chakravarthy S; Gakhar L; Schnicker NJ; Houtman JCD
    Sci Rep; 2023 Mar; 13(1):3505. PubMed ID: 36864087
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Interdomain interactions in Grb2 revealed by the conformational stability and CD28 binding analysis.
    Ochi S; Iiyama M; Oda M
    Biophys Chem; 2022 May; 284():106792. PubMed ID: 35276477
    [TBL] [Abstract][Full Text] [Related]  

  • 4. High resolution crystal structure of the Grb2 SH2 domain with a phosphopeptide derived from CD28.
    Higo K; Ikura T; Oda M; Morii H; Takahashi J; Abe R; Ito N
    PLoS One; 2013; 8(9):e74482. PubMed ID: 24098653
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Crystal Structures and Thermodynamic Analysis Reveal Distinct Mechanisms of CD28 Phosphopeptide Binding to the Src Homology 2 (SH2) Domains of Three Adaptor Proteins.
    Inaba S; Numoto N; Ogawa S; Morii H; Ikura T; Abe R; Ito N; Oda M
    J Biol Chem; 2017 Jan; 292(3):1052-1060. PubMed ID: 27927989
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Structural and energetic aspects of Grb2-SH2 domain-swapping.
    Benfield AP; Whiddon BB; Clements JH; Martin SF
    Arch Biochem Biophys; 2007 Jun; 462(1):47-53. PubMed ID: 17466257
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Crystal structures of the SH2 domain of Grb2: highlight on the binding of a new high-affinity inhibitor.
    Nioche P; Liu WQ; Broutin I; Charbonnier F; Latreille MT; Vidal M; Roques B; Garbay C; Ducruix A
    J Mol Biol; 2002 Feb; 315(5):1167-77. PubMed ID: 11827484
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Growth factor receptor-bound protein 2 SH2/SH3 domain binding to CD28 and its role in co-signaling.
    Kim HH; Tharayil M; Rudd CE
    J Biol Chem; 1998 Jan; 273(1):296-301. PubMed ID: 9417079
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Dimer formation through domain swapping in the crystal structure of the Grb2-SH2-Ac-pYVNV complex.
    Schiering N; Casale E; Caccia P; Giordano P; Battistini C
    Biochemistry; 2000 Nov; 39(44):13376-82. PubMed ID: 11063574
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Quantitative analysis by surface plasmon resonance of CD28 interaction with cytoplasmic adaptor molecules Grb2, Gads and p85 PI3K.
    Higo K; Oda M; Morii H; Takahashi J; Harada Y; Ogawa S; Abe R
    Immunol Invest; 2014; 43(3):278-91. PubMed ID: 24475931
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Structural and biophysical investigation of the interaction of a mutant Grb2 SH2 domain (W121G) with its cognate phosphopeptide.
    Papaioannou D; Geibel S; Kunze MB; Kay CW; Waksman G
    Protein Sci; 2016 Mar; 25(3):627-37. PubMed ID: 26645482
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Regulation of CD28 binding to SH2 domains of Grb2 and PI3K by trisubstituted carboranes for T-cell activation.
    Ogawa S; Asawa Y; Iiyama M; Yoshimori A; Nakamura H; Oda M
    Bioorg Med Chem Lett; 2022 Dec; 78():129049. PubMed ID: 36356833
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Tight association of GRB2 with receptor protein-tyrosine phosphatase alpha is mediated by the SH2 and C-terminal SH3 domains.
    den Hertog J; Hunter T
    EMBO J; 1996 Jun; 15(12):3016-27. PubMed ID: 8670803
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Solution structure of the SH2 domain of Grb2 complexed with the Shc-derived phosphotyrosine-containing peptide.
    Ogura K; Tsuchiya S; Terasawa H; Yuzawa S; Hatanaka H; Mandiyan V; Schlessinger J; Inagaki F
    J Mol Biol; 1999 Jun; 289(3):439-45. PubMed ID: 10356320
    [TBL] [Abstract][Full Text] [Related]  

  • 15. The C-terminal SH3 domain of the adapter protein Grb2 binds with high affinity to sequences in Gab1 and SLP-76 which lack the SH3-typical P-x-x-P core motif.
    Lewitzky M; Kardinal C; Gehring NH; Schmidt EK; Konkol B; Eulitz M; Birchmeier W; Schaeper U; Feller SM
    Oncogene; 2001 Mar; 20(9):1052-62. PubMed ID: 11314042
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Changes in structural dynamics of the Grb2 adaptor protein upon binding of phosphotyrosine ligand to its SH2 domain.
    de Mol NJ; Catalina MI; Fischer MJ; Broutin I; Maier CS; Heck AJ
    Biochim Biophys Acta; 2004 Jul; 1700(1):53-64. PubMed ID: 15210125
    [TBL] [Abstract][Full Text] [Related]  

  • 17. GRID: a novel Grb-2-related adapter protein that interacts with the activated T cell costimulatory receptor CD28.
    Ellis JH; Ashman C; Burden MN; Kilpatrick KE; Morse MA; Hamblin PA
    J Immunol; 2000 Jun; 164(11):5805-14. PubMed ID: 10820259
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Thermodynamic and structural analysis of phosphotyrosine polypeptide binding to Grb2-SH2.
    McNemar C; Snow ME; Windsor WT; Prongay A; Mui P; Zhang R; Durkin J; Le HV; Weber PC
    Biochemistry; 1997 Aug; 36(33):10006-14. PubMed ID: 9254595
    [TBL] [Abstract][Full Text] [Related]  

  • 19. The Role of Grb2 in Cancer and Peptides as Grb2 Antagonists.
    Ijaz M; Wang F; Shahbaz M; Jiang W; Fathy AH; Nesa EU
    Protein Pept Lett; 2018 Feb; 24(12):1084-1095. PubMed ID: 29173143
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Solution structure of the Grb2 SH2 domain complexed with a high-affinity inhibitor.
    Ogura K; Shiga T; Yokochi M; Yuzawa S; Burke TR; Inagaki F
    J Biomol NMR; 2008 Nov; 42(3):197-207. PubMed ID: 18830565
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.