441 related articles for article (PubMed ID: 30924108)
1. Dynasore Suppresses mTORC1 Activity and Induces Autophagy to Regulate the Clearance of Protein Aggregates in Neurodegenerative Diseases.
Chen Y; Xu S; Wang N; Ma Q; Peng P; Yu Y; Zhang L; Ying Z; Wang H
Neurotox Res; 2019 Jul; 36(1):108-116. PubMed ID: 30924108
[TBL] [Abstract][Full Text] [Related]
2. Ibudilast enhances the clearance of SOD1 and TDP-43 aggregates through TFEB-mediated autophagy and lysosomal biogenesis: The new molecular mechanism of ibudilast and its implication for neuroprotective therapy.
Chen Y; Wang H; Ying Z; Gao Q
Biochem Biophys Res Commun; 2020 May; 526(1):231-238. PubMed ID: 32204915
[TBL] [Abstract][Full Text] [Related]
3. TRIM37 deficiency induces autophagy through deregulating the MTORC1-TFEB axis.
Wang W; Xia Z; Farré JC; Subramani S
Autophagy; 2018; 14(9):1574-1585. PubMed ID: 29940807
[TBL] [Abstract][Full Text] [Related]
4. AKT inhibition-mediated dephosphorylation of TFE3 promotes overactive autophagy independent of MTORC1 in cadmium-exposed bone mesenchymal stem cells.
Pi H; Li M; Zou L; Yang M; Deng P; Fan T; Liu M; Tian L; Tu M; Xie J; Chen M; Li H; Xi Y; Zhang L; He M; Lu Y; Chen C; Zhang T; Wang Z; Yu Z; Gao F; Zhou Z
Autophagy; 2019 Apr; 15(4):565-582. PubMed ID: 30324847
[TBL] [Abstract][Full Text] [Related]
5. TDP-43 loss of function increases TFEB activity and blocks autophagosome-lysosome fusion.
Xia Q; Wang H; Hao Z; Fu C; Hu Q; Gao F; Ren H; Chen D; Han J; Ying Z; Wang G
EMBO J; 2016 Jan; 35(2):121-42. PubMed ID: 26702100
[TBL] [Abstract][Full Text] [Related]
6. mTOR hyperactivity mediates lysosomal dysfunction in Gaucher's disease iPSC-neuronal cells.
Brown RA; Voit A; Srikanth MP; Thayer JA; Kingsbury TJ; Jacobson MA; Lipinski MM; Feldman RA; Awad O
Dis Model Mech; 2019 Oct; 12(10):. PubMed ID: 31519738
[TBL] [Abstract][Full Text] [Related]
7. TFEB-driven endocytosis coordinates MTORC1 signaling and autophagy.
Nnah IC; Wang B; Saqcena C; Weber GF; Bonder EM; Bagley D; De Cegli R; Napolitano G; Medina DL; Ballabio A; Dobrowolski R
Autophagy; 2019 Jan; 15(1):151-164. PubMed ID: 30145926
[TBL] [Abstract][Full Text] [Related]
8. Trehalose causes low-grade lysosomal stress to activate TFEB and the autophagy-lysosome biogenesis response.
Jeong SJ; Stitham J; Evans TD; Zhang X; Rodriguez-Velez A; Yeh YS; Tao J; Takabatake K; Epelman S; Lodhi IJ; Schilling JD; DeBosch BJ; Diwan A; Razani B
Autophagy; 2021 Nov; 17(11):3740-3752. PubMed ID: 33706671
[TBL] [Abstract][Full Text] [Related]
9. VCP maintains lysosomal homeostasis and TFEB activity in differentiated skeletal muscle.
Arhzaouy K; Papadopoulos C; Schulze N; Pittman SK; Meyer H; Weihl CC
Autophagy; 2019 Jun; 15(6):1082-1099. PubMed ID: 30654731
[TBL] [Abstract][Full Text] [Related]
10. mTORC1-independent TFEB activation via Akt inhibition promotes cellular clearance in neurodegenerative storage diseases.
Palmieri M; Pal R; Nelvagal HR; Lotfi P; Stinnett GR; Seymour ML; Chaudhury A; Bajaj L; Bondar VV; Bremner L; Saleem U; Tse DY; Sanagasetti D; Wu SM; Neilson JR; Pereira FA; Pautler RG; Rodney GG; Cooper JD; Sardiello M
Nat Commun; 2017 Feb; 8():14338. PubMed ID: 28165011
[TBL] [Abstract][Full Text] [Related]
11. Oblongifolin C suppresses lysosomal function independently of TFEB nuclear translocation.
Wu M; Lao YZ; Tan HS; Lu G; Ren Y; Zheng ZQ; Yi J; Fu WW; Shen HM; Xu HX
Acta Pharmacol Sin; 2019 Jul; 40(7):929-937. PubMed ID: 30333555
[TBL] [Abstract][Full Text] [Related]
12. Cu(II) disrupts autophagy-mediated lysosomal degradation of oligomeric Aβ in microglia via mTOR-TFEB pathway.
Tan X; Guan H; Yang Y; Luo S; Hou L; Chen H; Li J
Toxicol Appl Pharmacol; 2020 Aug; 401():115090. PubMed ID: 32512069
[TBL] [Abstract][Full Text] [Related]
13. Neurodegenerative VPS41 variants inhibit HOPS function and mTORC1-dependent TFEB/TFE3 regulation.
van der Welle REN; Jobling R; Burns C; Sanza P; van der Beek JA; Fasano A; Chen L; Zwartkruis FJ; Zwakenberg S; Griffin EF; Ten Brink C; Veenendaal T; Liv N; van Ravenswaaij-Arts CMA; Lemmink HH; Pfundt R; Blaser S; Sepulveda C; Lozano AM; Yoon G; Santiago-Sim T; Asensio CS; Caldwell GA; Caldwell KA; Chitayat D; Klumperman J
EMBO Mol Med; 2021 May; 13(5):e13258. PubMed ID: 33851776
[TBL] [Abstract][Full Text] [Related]
14. PEX5 regulates autophagy via the mTORC1-TFEB axis during starvation.
Eun SY; Lee JN; Nam IK; Liu ZQ; So HS; Choe SK; Park R
Exp Mol Med; 2018 Apr; 50(4):1-12. PubMed ID: 29622767
[TBL] [Abstract][Full Text] [Related]
15. Chloroquine and bafilomycin A mimic lysosomal storage disorders and impair mTORC1 signalling.
Fedele AO; Proud CG
Biosci Rep; 2020 Apr; 40(4):. PubMed ID: 32285908
[TBL] [Abstract][Full Text] [Related]
16. Importance of TFEB acetylation in control of its transcriptional activity and lysosomal function in response to histone deacetylase inhibitors.
Zhang J; Wang J; Zhou Z; Park JE; Wang L; Wu S; Sun X; Lu L; Wang T; Lin Q; Sze SK; Huang D; Shen HM
Autophagy; 2018; 14(6):1043-1059. PubMed ID: 30059277
[TBL] [Abstract][Full Text] [Related]
17. Oxidation of multiple MiT/TFE transcription factors links oxidative stress to transcriptional control of autophagy and lysosome biogenesis.
Wang H; Wang N; Xu D; Ma Q; Chen Y; Xu S; Xia Q; Zhang Y; Prehn JHM; Wang G; Ying Z
Autophagy; 2020 Sep; 16(9):1683-1696. PubMed ID: 31826695
[TBL] [Abstract][Full Text] [Related]
18. TFEB activation protects against cardiac proteotoxicity via increasing autophagic flux.
Pan B; Zhang H; Cui T; Wang X
J Mol Cell Cardiol; 2017 Dec; 113():51-62. PubMed ID: 28993153
[TBL] [Abstract][Full Text] [Related]
19. Abnormal Cholesterol Metabolism and Lysosomal Dysfunction Induce Age-Related Hearing Loss by Inhibiting mTORC1-TFEB-Dependent Autophagy.
Lee YY; Ha J; Kim YS; Ramani S; Sung S; Gil ES; Choo OS; Jang JH; Choung YH
Int J Mol Sci; 2023 Dec; 24(24):. PubMed ID: 38139347
[TBL] [Abstract][Full Text] [Related]
20. The anti-tumor agent, Dp44mT, promotes nuclear translocation of TFEB via inhibition of the AMPK-mTORC1 axis.
Krishan S; Sahni S; Richardson DR
Biochim Biophys Acta Mol Basis Dis; 2020 Dec; 1866(12):165970. PubMed ID: 32950675
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
