351 related articles for article (PubMed ID: 30926669)
1. Precise small-molecule cleavage of an r(CUG) repeat expansion in a myotonic dystrophy mouse model.
Angelbello AJ; Rzuczek SG; Mckee KK; Chen JL; Olafson H; Cameron MD; Moss WN; Wang ET; Disney MD
Proc Natl Acad Sci U S A; 2019 Apr; 116(16):7799-7804. PubMed ID: 30926669
[TBL] [Abstract][Full Text] [Related]
2. Rationally designed small molecules that target both the DNA and RNA causing myotonic dystrophy type 1.
Nguyen L; Luu LM; Peng S; Serrano JF; Chan HY; Zimmerman SC
J Am Chem Soc; 2015 Nov; 137(44):14180-9. PubMed ID: 26473464
[TBL] [Abstract][Full Text] [Related]
3. Short antisense-locked nucleic acids (all-LNAs) correct alternative splicing abnormalities in myotonic dystrophy.
Wojtkowiak-Szlachcic A; Taylor K; Stepniak-Konieczna E; Sznajder LJ; Mykowska A; Sroka J; Thornton CA; Sobczak K
Nucleic Acids Res; 2015 Mar; 43(6):3318-31. PubMed ID: 25753670
[TBL] [Abstract][Full Text] [Related]
4. A CTG repeat-selective chemical screen identifies microtubule inhibitors as selective modulators of toxic CUG RNA levels.
Reddy K; Jenquin JR; McConnell OL; Cleary JD; Richardson JI; Pinto BS; Haerle MC; Delgado E; Planco L; Nakamori M; Wang ET; Berglund JA
Proc Natl Acad Sci U S A; 2019 Oct; 116(42):20991-21000. PubMed ID: 31570586
[TBL] [Abstract][Full Text] [Related]
5. Furamidine Rescues Myotonic Dystrophy Type I Associated Mis-Splicing through Multiple Mechanisms.
Jenquin JR; Coonrod LA; Silverglate QA; Pellitier NA; Hale MA; Xia G; Nakamori M; Berglund JA
ACS Chem Biol; 2018 Sep; 13(9):2708-2718. PubMed ID: 30118588
[TBL] [Abstract][Full Text] [Related]
6. Systemic delivery of a Peptide-linked morpholino oligonucleotide neutralizes mutant RNA toxicity in a mouse model of myotonic dystrophy.
Leger AJ; Mosquea LM; Clayton NP; Wu IH; Weeden T; Nelson CA; Phillips L; Roberts E; Piepenhagen PA; Cheng SH; Wentworth BM
Nucleic Acid Ther; 2013 Apr; 23(2):109-17. PubMed ID: 23308382
[TBL] [Abstract][Full Text] [Related]
7. Precise Targeted Cleavage of a r(CUG) Repeat Expansion in Cells by Using a Small-Molecule-Deglycobleomycin Conjugate.
Angelbello AJ; DeFeo ME; Glinkerman CM; Boger DL; Disney MD
ACS Chem Biol; 2020 Apr; 15(4):849-855. PubMed ID: 32186845
[TBL] [Abstract][Full Text] [Related]
8. Systemic Evaluation of Chimeric LNA/2'-O-Methyl Steric Blockers for Myotonic Dystrophy Type 1 Therapy.
Christou M; Wengel J; Sokratous K; Kyriacou K; Nikolaou G; Phylactou LA; Mastroyiannopoulos NP
Nucleic Acid Ther; 2020 Apr; 30(2):80-93. PubMed ID: 31873063
[TBL] [Abstract][Full Text] [Related]
9. MBNL1 and CUGBP1 modify expanded CUG-induced toxicity in a Drosophila model of myotonic dystrophy type 1.
de Haro M; Al-Ramahi I; De Gouyon B; Ukani L; Rosa A; Faustino NA; Ashizawa T; Cooper TA; Botas J
Hum Mol Genet; 2006 Jul; 15(13):2138-45. PubMed ID: 16723374
[TBL] [Abstract][Full Text] [Related]
10. Cytoplasmic CUG RNA foci are insufficient to elicit key DM1 features.
Dansithong W; Wolf CM; Sarkar P; Paul S; Chiang A; Holt I; Morris GE; Branco D; Sherwood MC; Comai L; Berul CI; Reddy S
PLoS One; 2008; 3(12):e3968. PubMed ID: 19092997
[TBL] [Abstract][Full Text] [Related]
11. Development of pharmacophore models for small molecules targeting RNA: Application to the RNA repeat expansion in myotonic dystrophy type 1.
Angelbello AJ; González ÀL; Rzuczek SG; Disney MD
Bioorg Med Chem Lett; 2016 Dec; 26(23):5792-5796. PubMed ID: 27839685
[TBL] [Abstract][Full Text] [Related]
12. Targeting toxic RNAs that cause myotonic dystrophy type 1 (DM1) with a bisamidinium inhibitor.
Wong CH; Nguyen L; Peh J; Luu LM; Sanchez JS; Richardson SL; Tuccinardi T; Tsoi H; Chan WY; Chan HY; Baranger AM; Hergenrother PJ; Zimmerman SC
J Am Chem Soc; 2014 Apr; 136(17):6355-61. PubMed ID: 24702247
[TBL] [Abstract][Full Text] [Related]
13. Colocalization of muscleblind with RNA foci is separable from mis-regulation of alternative splicing in myotonic dystrophy.
Ho TH; Savkur RS; Poulos MG; Mancini MA; Swanson MS; Cooper TA
J Cell Sci; 2005 Jul; 118(Pt 13):2923-33. PubMed ID: 15961406
[TBL] [Abstract][Full Text] [Related]
14. RNA interference targeting CUG repeats in a mouse model of myotonic dystrophy.
Sobczak K; Wheeler TM; Wang W; Thornton CA
Mol Ther; 2013 Feb; 21(2):380-7. PubMed ID: 23183533
[TBL] [Abstract][Full Text] [Related]
15. Rationally designed small molecules targeting the RNA that causes myotonic dystrophy type 1 are potently bioactive.
Childs-Disney JL; Hoskins J; Rzuczek SG; Thornton CA; Disney MD
ACS Chem Biol; 2012 May; 7(5):856-62. PubMed ID: 22332923
[TBL] [Abstract][Full Text] [Related]
16. In silico discovery of substituted pyrido[2,3-d]pyrimidines and pentamidine-like compounds with biological activity in myotonic dystrophy models.
González ÀL; Konieczny P; Llamusi B; Delgado-Pinar E; Borrell JI; Teixidó J; García-España E; Pérez-Alonso M; Estrada-Tejedor R; Artero R
PLoS One; 2017; 12(6):e0178931. PubMed ID: 28582438
[TBL] [Abstract][Full Text] [Related]
17. A novel CUG(exp)·MBNL1 inhibitor with therapeutic potential for myotonic dystrophy type 1.
Jahromi AH; Nguyen L; Fu Y; Miller KA; Baranger AM; Zimmerman SC
ACS Chem Biol; 2013 May; 8(5):1037-43. PubMed ID: 23480597
[TBL] [Abstract][Full Text] [Related]
18. Daunorubicin reduces MBNL1 sequestration caused by CUG-repeat expansion and rescues cardiac dysfunctions in a
Chakraborty M; Sellier C; Ney M; Pascal V; Charlet-Berguerand N; Artero R; Llamusi B
Dis Model Mech; 2018 Apr; 11(4):. PubMed ID: 29592894
[TBL] [Abstract][Full Text] [Related]
19. Ribonuclear foci at the neuromuscular junction in myotonic dystrophy type 1.
Wheeler TM; Krym MC; Thornton CA
Neuromuscul Disord; 2007 Mar; 17(3):242-7. PubMed ID: 17306536
[TBL] [Abstract][Full Text] [Related]
20. A flow cytometry-based screen identifies MBNL1 modulators that rescue splicing defects in myotonic dystrophy type I.
Zhang F; Bodycombe NE; Haskell KM; Sun YL; Wang ET; Morris CA; Jones LH; Wood LD; Pletcher MT
Hum Mol Genet; 2017 Aug; 26(16):3056-3068. PubMed ID: 28535287
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
