484 related articles for article (PubMed ID: 30927565)
1. Design, synthesis and biological evaluation of novel uracil derivatives bearing 1, 2, 3-triazole moiety as thymidylate synthase (TS) inhibitors and as potential antitumor drugs.
Lu GQ; Li XY; Mohamed O K; Wang D; Meng FH
Eur J Med Chem; 2019 Jun; 171():282-296. PubMed ID: 30927565
[TBL] [Abstract][Full Text] [Related]
2. Design, synthesis and biological evaluation of N-phenyl-(2,4-dihydroxypyrimidine-5-sulfonamido)benzoyl hydrazide derivatives as thymidylate synthase (TS) inhibitors and as potential antitumor drugs.
Li XY; Liang JW; Mohamed O K; Zhang TJ; Lu GQ; Meng FH
Eur J Med Chem; 2018 Jun; 154():267-279. PubMed ID: 29807332
[TBL] [Abstract][Full Text] [Related]
3. Design, synthesis and biological evaluation of homoerythrina alkaloid derivatives bearing a triazole moiety as PARP-1 inhibitors and as potential antitumor drugs.
Li S; Li XY; Zhang TJ; Kamara MO; Liang JW; Zhu J; Meng FH
Bioorg Chem; 2020 Jan; 94():103385. PubMed ID: 31669094
[TBL] [Abstract][Full Text] [Related]
4. Discovery of N-phenyl-(2,4-dihydroxypyrimidine-5-sulfonamido) phenylurea-based thymidylate synthase (TS) inhibitor as a novel multi-effects antitumor drugs with minimal toxicity.
Li XY; Zhang TJ; Kamara MO; Lu GQ; Xu HL; Wang DP; Meng FH
Cell Death Dis; 2019 Jul; 10(7):532. PubMed ID: 31296849
[TBL] [Abstract][Full Text] [Related]
5. Design, synthesis, anticancer evaluation and docking studies of new pyrimidine derivatives as potent thymidylate synthase inhibitors.
Amin LHT; Shawer TZ; El-Naggar AM; El-Sehrawi HMA
Bioorg Chem; 2019 Oct; 91():103159. PubMed ID: 31382056
[TBL] [Abstract][Full Text] [Related]
6. Novel benzotriazole N-acylarylhydrazone hybrids: Design, synthesis, anticancer activity, effects on cell cycle profile, caspase-3 mediated apoptosis and FAK inhibition.
Kassab AE; Hassan RA
Bioorg Chem; 2018 Oct; 80():531-544. PubMed ID: 30014921
[TBL] [Abstract][Full Text] [Related]
7. Design and synthesis of novel 1,2,3-triazole-pyrimidine hybrids as potential anticancer agents.
Ma LY; Pang LP; Wang B; Zhang M; Hu B; Xue DQ; Shao KP; Zhang BL; Liu Y; Zhang E; Liu HM
Eur J Med Chem; 2014 Oct; 86():368-80. PubMed ID: 25180925
[TBL] [Abstract][Full Text] [Related]
8. Design, synthesis and
Alzhrani ZMM; Alam MM; Neamatallah T; Nazreen S
J Enzyme Inhib Med Chem; 2020 Dec; 35(1):1116-1123. PubMed ID: 32354237
[TBL] [Abstract][Full Text] [Related]
9. Novel 6-substituted benzoyl and non-benzoyl straight chain pyrrolo[2,3-d]pyrimidines as potential antitumor agents with multitargeted inhibition of TS, GARFTase and AICARFTase.
Xing R; Zhang H; Yuan J; Zhang K; Li L; Guo H; Zhao L; Zhang C; Li S; Gao T; Liu Y; Wang L
Eur J Med Chem; 2017 Oct; 139():531-541. PubMed ID: 28830032
[TBL] [Abstract][Full Text] [Related]
10. Design, synthesis and biological evaluation of novel 3-alkylsulfanyl-4-amino-1,2,4-triazole derivatives.
Zhao PL; Chen P; Li Q; Hu MJ; Diao PC; Pan ES; You WW
Bioorg Med Chem Lett; 2016 Aug; 26(15):3679-83. PubMed ID: 27287368
[TBL] [Abstract][Full Text] [Related]
11. Design, synthesis and biological evaluation of novel 6-substituted pyrrolo [3,2-d] pyrimidine analogues as antifolate antitumor agents.
Tian C; Wang M; Han Z; Fang F; Zhang Z; Wang X; Liu J
Eur J Med Chem; 2017 Sep; 138():630-643. PubMed ID: 28711701
[TBL] [Abstract][Full Text] [Related]
12. Synthesis, characterization and molecular docking studies of thiouracil derivatives as potent thymidylate synthase inhibitors and potential anticancer agents.
El-Naggar AM; Abou-El-Regal MM; El-Metwally SA; Sherbiny FF; Eissa IH
Mol Divers; 2017 Nov; 21(4):967-983. PubMed ID: 28815411
[TBL] [Abstract][Full Text] [Related]
13. Design and synthesis of novel 1,2,3-triazole-dithiocarbamate hybrids as potential anticancer agents.
Duan YC; Ma YC; Zhang E; Shi XJ; Wang MM; Ye XW; Liu HM
Eur J Med Chem; 2013 Apr; 62():11-9. PubMed ID: 23353743
[TBL] [Abstract][Full Text] [Related]
14. Cyclic Peptides Acting as Allosteric Inhibitors of Human Thymidylate Synthase and Cancer Cell Growth.
Pacifico S; Santucci M; Luciani R; Saxena P; Linciano P; Ponterini G; Lauriola A; D'Arca D; Marverti G; Guerrini R; Costi MP
Molecules; 2019 Sep; 24(19):. PubMed ID: 31561530
[TBL] [Abstract][Full Text] [Related]
15. 1,2,3-Triazole-containing uracil derivatives with excellent pharmacokinetics as a novel class of potent human deoxyuridine triphosphatase inhibitors.
Miyakoshi H; Miyahara S; Yokogawa T; Endoh K; Muto T; Yano W; Wakasa T; Ueno H; Chong KT; Taguchi J; Nomura M; Takao Y; Fujioka A; Hashimoto A; Itou K; Yamamura K; Shuto S; Nagasawa H; Fukuoka M
J Med Chem; 2012 Jul; 55(14):6427-37. PubMed ID: 22715973
[TBL] [Abstract][Full Text] [Related]
16. Novel 1,3,4-oxadiazole thioether derivatives targeting thymidylate synthase as dual anticancer/antimicrobial agents.
Du QR; Li DD; Pi YZ; Li JR; Sun J; Fang F; Zhong WQ; Gong HB; Zhu HL
Bioorg Med Chem; 2013 Apr; 21(8):2286-2297. PubMed ID: 23490159
[TBL] [Abstract][Full Text] [Related]
17. Design, synthesis and antiproliferative activity studies of novel 1,2,3-triazole-dithiocarbamate-urea hybrids.
Duan YC; Zheng YC; Li XC; Wang MM; Ye XW; Guan YY; Liu GZ; Zheng JX; Liu HM
Eur J Med Chem; 2013 Jun; 64():99-110. PubMed ID: 23644193
[TBL] [Abstract][Full Text] [Related]
18. Synthesis and biological evaluation of novel 7-hydroxy-4-phenylchromen-2-one-linked to triazole moieties as potent cytotoxic agents.
Liu CF; Shen QK; Li JJ; Tian YS; Quan Z
J Enzyme Inhib Med Chem; 2017 Dec; 32(1):1111-1119. PubMed ID: 28791908
[TBL] [Abstract][Full Text] [Related]
19. Expanding the anticancer potential of 1,2,3-triazoles via simultaneously targeting Cyclooxygenase-2, 15-lipoxygenase and tumor-associated carbonic anhydrases.
Elzahhar PA; Abd El Wahab SM; Elagawany M; Daabees H; Belal ASF; El-Yazbi AF; Eid AH; Alaaeddine R; Hegazy RR; Allam RM; Helmy MW; Bahaa Elgendy ; Angeli A; El-Hawash SA; Supuran CT
Eur J Med Chem; 2020 Aug; 200():112439. PubMed ID: 32485532
[TBL] [Abstract][Full Text] [Related]
20. Synthesis, antitumor activity evaluation and mechanistic study of novel hederacolchiside A
Li HN; Wang H; Wang ZP; Yan HN; Zhang M; Liu Y; Cheng MS
Bioorg Med Chem; 2018 Aug; 26(14):4025-4033. PubMed ID: 29958763
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]