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2. In vitro and in vivo activity of cabozantinib (XL184), an inhibitor of RET, MET, and VEGFR2, in a model of medullary thyroid cancer. Bentzien F; Zuzow M; Heald N; Gibson A; Shi Y; Goon L; Yu P; Engst S; Zhang W; Huang D; Zhao L; Vysotskaia V; Chu F; Bautista R; Cancilla B; Lamb P; Joly AH; Yakes FM Thyroid; 2013 Dec; 23(12):1569-77. PubMed ID: 23705946 [TBL] [Abstract][Full Text] [Related]
3. Combination of RET siRNA and irinotecan inhibited the growth of medullary thyroid carcinoma TT cells and xenografts via apoptosis. Koga K; Hattori Y; Komori M; Narishima R; Yamasaki M; Hakoshima M; Fukui T; Maitani Y Cancer Sci; 2010 Apr; 101(4):941-7. PubMed ID: 20704575 [TBL] [Abstract][Full Text] [Related]
4. The HIV protease inhibitor nelfinavir down-regulates RET signaling and induces apoptosis in medullary thyroid cancer cells. Kushchayeva Y; Jensen K; Recupero A; Costello J; Patel A; Klubo-Gwiezdzinska J; Boyle L; Burman K; Vasko V J Clin Endocrinol Metab; 2014 May; 99(5):E734-45. PubMed ID: 24483157 [TBL] [Abstract][Full Text] [Related]
5. Mortalin (GRP75/HSPA9) upregulation promotes survival and proliferation of medullary thyroid carcinoma cells. Starenki D; Hong SK; Lloyd RV; Park JI Oncogene; 2015 Aug; 34(35):4624-34. PubMed ID: 25435367 [TBL] [Abstract][Full Text] [Related]
6. Medullary thyroid carcinoma cell lines contain a self-renewing CD133+ population that is dependent on ret proto-oncogene activity. Zhu W; Hai T; Ye L; Cote GJ J Clin Endocrinol Metab; 2010 Jan; 95(1):439-44. PubMed ID: 19897677 [TBL] [Abstract][Full Text] [Related]
7. MiR-129-5p is down-regulated and involved in the growth, apoptosis and migration of medullary thyroid carcinoma cells through targeting RET. Duan L; Hao X; Liu Z; Zhang Y; Zhang G FEBS Lett; 2014 May; 588(9):1644-51. PubMed ID: 24631532 [TBL] [Abstract][Full Text] [Related]
8. MiR-182 promotes cancer invasion by linking RET oncogene activated NF-κB to loss of the HES1/Notch1 regulatory circuit. Spitschak A; Meier C; Kowtharapu B; Engelmann D; Pützer BM Mol Cancer; 2017 Jan; 16(1):24. PubMed ID: 28122586 [TBL] [Abstract][Full Text] [Related]
9. Role of MEN2A-derived RET in maintenance and proliferation of medullary thyroid carcinoma. Drosten M; Hilken G; Böckmann M; Rödicker F; Mise N; Cranston AN; Dahmen U; Ponder BA; Pützer BM J Natl Cancer Inst; 2004 Aug; 96(16):1231-9. PubMed ID: 15316058 [TBL] [Abstract][Full Text] [Related]
10. ATF4 Targets RET for Degradation and Is a Candidate Tumor Suppressor Gene in Medullary Thyroid Cancer. Bagheri-Yarmand R; Williams MD; Grubbs EG; Gagel RF J Clin Endocrinol Metab; 2017 Mar; 102(3):933-941. PubMed ID: 27935748 [TBL] [Abstract][Full Text] [Related]
11. Cellular effects of imatinib on medullary thyroid cancer cells harboring multiple endocrine neoplasia Type 2A and 2B associated RET mutations. de Groot JW; Plaza Menacho I; Schepers H; Drenth-Diephuis LJ; Osinga J; Plukker JT; Links TP; Eggen BJ; Hofstra RM Surgery; 2006 Jun; 139(6):806-14. PubMed ID: 16782438 [TBL] [Abstract][Full Text] [Related]
12. Proteomics study of medullary thyroid carcinomas expressing RET germ-line mutations: identification of new signaling elements. Gorla L; Mondellini P; Cuccuru G; Miccichè F; Cassinelli G; Cremona M; Pierotti MA; Lanzi C; Bongarzone I Mol Carcinog; 2009 Mar; 48(3):220-231. PubMed ID: 18756447 [TBL] [Abstract][Full Text] [Related]
13. In vitro transforming potential, intracellular signaling properties, and sensitivity to a kinase inhibitor (sorafenib) of RET proto-oncogene variants Glu511Lys, Ser649Leu, and Arg886Trp. Prazeres H; Couto JP; Rodrigues F; Vinagre J; Torres J; Trovisco V; Martins TC; Sobrinho-Simões M; Soares P Endocr Relat Cancer; 2011 Aug; 18(4):401-12. PubMed ID: 21551259 [TBL] [Abstract][Full Text] [Related]
14. Medullary Thyroid Cancer - Feature Review and Update on Systemic Treatment. Dabelić N; Jukić T; Fröbe A Acta Clin Croat; 2020 Jun; 59(Suppl 1):50-59. PubMed ID: 34219884 [TBL] [Abstract][Full Text] [Related]
15. Antitumor capacity of a dominant-negative RET proto-oncogene mutant in a medullary thyroid carcinoma model. Drosten M; Stiewe T; Pützer BM Hum Gene Ther; 2003 Jul; 14(10):971-82. PubMed ID: 12869215 [TBL] [Abstract][Full Text] [Related]
16. Recombinant leukemia inhibitory factor suppresses human medullary thyroid carcinoma cell line xenografts in mice. Starenki D; Singh NK; Jensen DR; Peterson FC; Park JI Cancer Lett; 2013 Oct; 339(1):144-51. PubMed ID: 23856028 [TBL] [Abstract][Full Text] [Related]
17. A transplantable human medullary thyroid carcinoma as a model for RET tyrosine kinase-driven tumorigenesis. Johanson V; Ahlman H; Bernhardt P; Jansson S; Kölby L; Persson F; Stenman G; Swärd C; Wängberg B; Stridsberg M; Nilsson O Endocr Relat Cancer; 2007 Jun; 14(2):433-44. PubMed ID: 17639056 [TBL] [Abstract][Full Text] [Related]