BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

190 related articles for article (PubMed ID: 30930056)

  • 1. Disruption of Telomerase RNA Maturation Kinetics Precipitates Disease.
    Roake CM; Chen L; Chakravarthy AL; Ferrell JE; Raffa GD; Artandi SE
    Mol Cell; 2019 May; 74(4):688-700.e3. PubMed ID: 30930056
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Inhibition of telomerase RNA decay rescues telomerase deficiency caused by dyskerin or PARN defects.
    Shukla S; Schmidt JC; Goldfarb KC; Cech TR; Parker R
    Nat Struct Mol Biol; 2016 Apr; 23(4):286-92. PubMed ID: 26950371
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Posttranscriptional modulation of TERC by PAPD5 inhibition rescues hematopoietic development in dyskeratosis congenita.
    Fok WC; Shukla S; Vessoni AT; Brenner KA; Parker R; Sturgeon CM; Batista LFZ
    Blood; 2019 Mar; 133(12):1308-1312. PubMed ID: 30728146
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Poly(A)-specific ribonuclease (PARN) mediates 3'-end maturation of the telomerase RNA component.
    Moon DH; Segal M; Boyraz B; Guinan E; Hofmann I; Cahan P; Tai AK; Agarwal S
    Nat Genet; 2015 Dec; 47(12):1482-8. PubMed ID: 26482878
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Posttranscriptional manipulation of TERC reverses molecular hallmarks of telomere disease.
    Boyraz B; Moon DH; Segal M; Muosieyiri MZ; Aykanat A; Tai AK; Cahan P; Agarwal S
    J Clin Invest; 2016 Sep; 126(9):3377-82. PubMed ID: 27482890
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Chemical inhibition of PAPD5/7 rescues telomerase function and hematopoiesis in dyskeratosis congenita.
    Shukla S; Jeong HC; Sturgeon CM; Parker R; Batista LFZ
    Blood Adv; 2020 Jun; 4(12):2717-2722. PubMed ID: 32559291
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Regulation of poly(a)-specific ribonuclease activity by reversible lysine acetylation.
    Dejene EA; Li Y; Showkatian Z; Ling H; Seto E
    J Biol Chem; 2020 Jul; 295(30):10255-10270. PubMed ID: 32457045
    [TBL] [Abstract][Full Text] [Related]  

  • 8. PARN Modulates Y RNA Stability and Its 3'-End Formation.
    Shukla S; Parker R
    Mol Cell Biol; 2017 Oct; 37(20):. PubMed ID: 28760775
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Distinct biogenesis pathways for human telomerase RNA and H/ACA small nucleolar RNAs.
    Fu D; Collins K
    Mol Cell; 2003 May; 11(5):1361-72. PubMed ID: 12769858
    [TBL] [Abstract][Full Text] [Related]  

  • 10. TOE1 acts as a 3' exonuclease for telomerase RNA and regulates telomere maintenance.
    Deng T; Huang Y; Weng K; Lin S; Li Y; Shi G; Chen Y; Huang J; Liu D; Ma W; Songyang Z
    Nucleic Acids Res; 2019 Jan; 47(1):391-405. PubMed ID: 30371886
    [TBL] [Abstract][Full Text] [Related]  

  • 11. The RNase PARN Controls the Levels of Specific miRNAs that Contribute to p53 Regulation.
    Shukla S; Bjerke GA; Muhlrad D; Yi R; Parker R
    Mol Cell; 2019 Mar; 73(6):1204-1216.e4. PubMed ID: 30770239
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Dyskeratosis congenita mutations in the H/ACA domain of human telomerase RNA affect its assembly into a pre-RNP.
    Trahan C; Dragon F
    RNA; 2009 Feb; 15(2):235-43. PubMed ID: 19095616
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Telomerase RNA mutated in autosomal dyskeratosis congenita reconstitutes a weakly active telomerase enzyme defective in telomere elongation.
    Cerone MA; Ward RJ; LondoƱo-Vallejo JA; Autexier C
    Cell Cycle; 2005 Apr; 4(4):585-9. PubMed ID: 15753647
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Telomere biology disorders: time for moving towards the clinic?
    Batista LFZ; Dokal I; Parker R
    Trends Mol Med; 2022 Oct; 28(10):882-891. PubMed ID: 36057525
    [TBL] [Abstract][Full Text] [Related]  

  • 15. N-terminal residues of human dyskerin are required for interactions with telomerase RNA that prevent RNA degradation.
    MacNeil DE; Lambert-Lanteigne P; Autexier C
    Nucleic Acids Res; 2019 Jun; 47(10):5368-5380. PubMed ID: 30931479
    [TBL] [Abstract][Full Text] [Related]  

  • 16. The H/ACA complex disrupts triplex in hTR precursor to permit processing by RRP6 and PARN.
    Tseng CK; Wang HF; Schroeder MR; Baumann P
    Nat Commun; 2018 Dec; 9(1):5430. PubMed ID: 30575725
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Single-molecule analysis of the human telomerase RNA.dyskerin interaction and the effect of dyskeratosis congenita mutations.
    Ashbridge B; Orte A; Yeoman JA; Kirwan M; Vulliamy T; Dokal I; Klenerman D; Balasubramanian S
    Biochemistry; 2009 Nov; 48(46):10858-65. PubMed ID: 19835419
    [TBL] [Abstract][Full Text] [Related]  

  • 18. A Polyadenylation-Dependent 3' End Maturation Pathway Is Required for the Synthesis of the Human Telomerase RNA.
    Nguyen D; Grenier St-Sauveur V; Bergeron D; Dupuis-Sandoval F; Scott MS; Bachand F
    Cell Rep; 2015 Dec; 13(10):2244-57. PubMed ID: 26628368
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Identification of a new RNA.RNA interaction site for human telomerase RNA (hTR): structural implications for hTR accumulation and a dyskeratosis congenita point mutation.
    Ren X; Gavory G; Li H; Ying L; Klenerman D; Balasubramanian S
    Nucleic Acids Res; 2003 Nov; 31(22):6509-15. PubMed ID: 14602909
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Human Telomerase RNA Processing and Quality Control.
    Tseng CK; Wang HF; Burns AM; Schroeder MR; Gaspari M; Baumann P
    Cell Rep; 2015 Dec; 13(10):2232-43. PubMed ID: 26628367
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.